Spanish Red Biotech Pipeline*

Transcripción

Spanish Red Biotech Pipeline
*
DRUGS: MULTINATIONAL SUBSIDIARIES **
Spanish Red Biotech Pipeline 2015
Company
D R UGS: M U LT INAT IONAL S U B SIDIA R IES
49,21%
15,48%
11,90% 11,51%
8,33%
6,35%
3,57%
6,35%
Ot
Wo
me hers
n´s
D
Car
i
g
est health
dio Musk
ive
vas
ulo
Sys
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ske
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and etal
cic Disor
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Cen latory ers
tra
sy
Me l Ner stem
s
tab
v
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ys
/E
ndo tem
Blo
crin
od
olo
and
gy
I
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L
f
ym
Aut
pha ection
oim
tic
s
mu
sys
ne
te
&I
nfla ms
mm
atio
n
Can
cer
2,38%
4,76%
5,56%
Product
Evolocumab
Talimogene laherparepvec
Cinacalcet
IFN ß 1a pgilated
BG-12
Aubagio® (teriflunomida)
Alemtuzumab
Eliglustat
Evofosfamida
Pimasertib
IDegAsp (combination insulin degludec + insulin aspart)
IDegLira (combination insulin degludec + liraglutide)
Liraglutide 3mg
Turoctocog alfa
Atrasentan
Elagolix
ABT-199/GDC0199
HCV Interferon-Free Combination (genotype 1)
Veliparib
Etelcalcetide
Romosozumab
Denosumab
Brodalumab
Brodalumab
Rilotumumab
Darbepoetin alfa
Blinatumomab
Trebananib
Daclizumab
REVLIMID® (lenalidomide)
CC 486
REVLIMID® (lenalidomide)
CC 486
OTEZLA® (Apremilast)
ABRAXANE®
VIDAZA® (azacitidine for injection)
Momelotinib
Ranolazine
Idelalisib
Emtricitabine/Tenofovir alafenamide FDC
Emtricitabine/Rilpivirine/Tenofovir alafenamide STR
Emtricitabine/Tenofovir alafenamide FDC
Elvitegravir/Cobicistat/Emtricitabine/Tenofovir alafenamide STR
Avelumab
Vacuna
Suvorexant
Rotavirus Vaccine
Remicade
Quadrivalent HPV
Posaconazol
Nonavalente HPV Vaccine
Letermovir
Inhibitor of human _-site APP cleaving enzyme (BACE1)
Inactivated VZV Vaccine
Inactivated VZV Vaccine
Golimumab
Ezetimiba + Simvastatina
Dinaciclib Ofatumumab
Corifollitropina
Boceprevir
Grazoprevir
Pembrolizumab
Pembrolizumab
Pembrolizumab
Pembrolizumab
Pembrolizumab
Pembrolizumab
Pembrolizumab
Pembrolizumab
Human Monoclonal Antibody to Clostridium difficile toxin A
Aprepitant
Anacetrapib
Pembrolizumab
Odanacatib
Raltegravir
Fosaprepitant
Fosaprepitant
Sitagliptina
Sitagliptina
Doravirina
Semaglutide
Liraglutide type 1
Nonacog beta pegol
N8-GP (glycopegylated recombinant FVIII)
Liraglutide
Faster-acting insulin aspart (FIAsp)
ALECTINIB
BITOPERTIN
OCRELIZUMAB
ALEGLITAZAR
ALEGLITAZAR
COBIMETINIB
ETROLIZUMAB
GANTENERUMAB
GAZYVA
GAZYVA
GAZYVA
GAZYVA
KADCYLA
KADCYLA
OCRELIZUMAB
OCRELIZUMAB
PDL1 MAB
ONARTUZUMAB
ONARTUZUMAB
PDL1 MAB
PERJETA
PERJETA
PERJETA
TASELISIB
VENETOCLAX
XOLAIR
ACTEMRA
ACTEMRA
ACTEMRA
AVASTIN
AVASTIN
AVASTIN
DALCETRAPIB
DALCETRAPIB
HCV POL INH PRO
LAMPALIZUMAB
MABTHERA
MABTHERA
MABTHERA
MABTHERA
MABTHERA
PEGASYS
TAMIFLU
TASPOGLUTIDE
VALCYTE
XELODA
ZELBORAF
Cx601
ABT-981
ABT-494
AMG 337
AMG 334
Conatumumab
AMG 181
Denosumab
Omecantiv mecarbil
Romoplostim
anti-TWEAK
antiLingo
Natalizumab
antiLingo
GED 0301
GS-5806 (fusion inhibitor)
GS-6615 (late sodium current inhibitor)
GS-4997 (ASK-1 inhibitor)
GS-5745 (MMP9 mAb inhibitor)
GS-5745 (MMP9 mAb inhibitor)
Momelotinib
GS-4997 (ASK-1 inhibitor)
Simtuzumab
Simtuzumab
Abituzumab
Atacicept
Thiazole
Ridaforolimus
Posaconazol
Pneumoccol Conjugate Vaccine
Etonogestrel
Dipeptidyl peptidase-IV (DPP-4) inhibitor
Dalotuzumab
Monoclonal antibody anti Il-21
Oral semaglutide
APITOLISIB
BASIMGLURANT
CMV ANTI
CRENEZUMAB
DANOPREVIR
DULIGOTUZUMAB
DULIGOTUZUMAB
EM ACTEMAB RA
GAZYVA
GAZYVA
GPC3 MAB
HPV16 TI
IGF1R MAB
IGF1R MAB
IMGATUZUMAB
IMGATUZUMAB
IPATASERTIB
IPATASERTIB
IPATASERTIB
KADCYLA
LEBRIKIZUMAB
MERICITABINE
ONARTUZUMAB
ONARTUZUMAB
PARSATUZUMAB
PDL1 MAB
PICTILISIB
PICTILISIB
SEMBRAGILINE
VANUCIZUMAB
ALPHA7 NIC AGO
ANTI-INFLUENZA A
AVASTIN
ERIVEDGE
ERIVEDGE
ERIVEDGE
FORTOVASE
HERCEPTIN
LIFASTUZUMAB VEDOTIN
NEORECORMON
PATECLIZUMAB
POLATUZUMAB VEDOTIN
TARCEVA
TARCEVA
XELODA
ZELBORAF
Cx611
ABBV-221
CC-122
Posaconazol
Pembrolizumab
Pembrolizumab
inhibitor of stearoyl-CoA desaturase
Long-acting growth hormone
Concizumab
APITOLISIB
APITOLISIB
BRAF KIN INH (2)
CEA IL2V
COBIMETINIB
COBIMETINIB
DULIGOTUZUMAB
EM RA PRED DEV
ETROLIZUMAB
IMGATUZUMAB
IMGATUZUMAB
IPATASERTIB
LUMRETUZUMAB
LUMRETUZUMAB
LUMRETUZUMAB
PDL1 MAB
PDL1 MAB
TASELISIB
VANUCIZUMAB
VENETOCLAX
CD40 IMAB
CEA CD3 TCB
CIF MEK INH
EM MS BIOMARKER
LIFASTUZUMAB VEDOTIN
OX40
PLGF MAB
Cx611
Cx621
Type
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
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Biodrugs / Drugs
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Biodrugs / Drugs
Biodrugs / Drugs
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Biodrugs / Drugs
Biodrugs / Drugs
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Biodrugs / Drugs
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Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Vaccines
Biodrugs / Drugs
Vaccines
Biodrugs / Drugs
Vaccines
Biodrugs / Drugs
Vaccines
Biodrugs / Drugs
Biodrugs / Drugs
Vaccines
Vaccines
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Gene / Cell Therapy
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Vaccines
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
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Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Gene / Cell Therapy
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
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Biodrugs / Drugs
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Biodrugs / Drugs
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Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Gene / Cell Therapy
Gene / Cell Therapy
Therapeutic area
Metabolic & Endocrinology / Cardiovascular and circulatory systems
Cancer
Kidney and Genitourinary system / Autoimmune & Inflammation
Central Nervous System / Autoimmune & Inflammation
Genetic Diseases and Dysmorphic syndromes / Metabolic & Endocrinology
Cancer / Dermatology / Digestive System
Cancer
Metabolic & Endocrinology
Blood and Lymphatic systems
Kidney and Genitourinary system
Women´s health
Cancer / Blood and Lymphatic systems
Infections
Cancer
Musculoskeletal Disorders / Women´s health
Musculoskeletal Disorders
Musculoskeletal Disorders / Autoimmune & Inflammation
Dermatology / Autoimmune & Inflammation
Cancer
Cancer
Blood and Lymphatic systems / Cancer
Autoimmune & Inflammation / Musculoskeletal Disorders
Cancer
Cardiovascular and circulatory systems
Infections
Infections
Infections
Infections
Cancer
Infections
Others
Infections
Autoimmune & Inflammation
Women´s health / Infections
Infections
Women´s health / Infections
Infections
Central Nervous System
Infections
Infections
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Infections
Cancer
Cancer
Musculoskeletal Disorders / Women´s health
Infections
Cancer
Cancer
Infections
Cancer
Cardiovascular and circulatory systems / Metabolic & Endocrinology
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Autoimmune & Inflammation / Dermatology
Cancer
Cancer
Cancer
Infections
Ophthalmology and optometry
Infections
Infections
Cancer
Cancer
Autoimmune & Inflammation / Digestive System
Analgesia & pain / Autoimmune & Inflammation
Cancer
Cancer
Cancer
Kidney and Genitourinary system / Autoimmune & Inflammation
Respiratory and Pulmonary system / Infections
Cancer
Cancer
Digestive System
Digestive System
Respiratory and Pulmonary system
Cancer
Cancer
Infections
Infections
Women´s health
Cancer
Cancer
Genetic Diseases and Dysmorphic syndromes
Infections
Infections
Cancer
Cancer
Cancer
Cancer
Infections
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Infections
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Infections
Cancer
Cancer
Cancer
Cancer / Autoimmune & Inflammation
Infections
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Infections
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Autoimmune & Inflammation / Infections
Indication
Hypercholesterolemia
Malignant melanoma
Post renal transplant
Multiple Sclerosis
Multiple Sclerosis
Multiple Sclerosis
Multiple Sclerosis
Lysosomal Diseases; Gaucher Disease
Pancreas, cancer, sarcoma
Colorectal Cancer, Pancreas, Melanoma, solid tumours and ovarian cancer
Diabetes type 2 and type 1
Diabetes type 2
Obesity
Haemophilia A
Diabetic Nephropathy
Endometriosis
Chronic Lymphocytic Laeukemia
Haepatitis C
Breast, ovarian and colorectal Cancer, Non-small-cell lung carcinoma (NSCLC)and Small Cell Lung Cancer (SCLC ), Triple-negative breast cancer (TNBC), solid tumors
Secondary Hyperparathyroidism
Postmenopausal osteoporosis
Bone-related conditions, glucocorticoids induced osteopenia, imperfect osteogenesis
Psoriatic arthritis
Psoriasis
Various cancer types
Myelodysplastic syndromes
Acute lymphoblastic leukaemia
Ovarian Cancer
Multiple Sclerosis
Lymphoma Diffuse large B-cell
Post-induction acute myeloid laeukemia (AML) maintenance
Maintenance: Second-line
Myelodysplastic syndrome (MDS) Lower-risk
Ankylosing spondylitis
Breast: Metastatic (1st-line, triple negative)
Acute myeloid laeukemia (AML) (>30% blasts)
Myelofibrosis
Incomplete revascularization post-PCI (Percutaneous Coronary Intervention)
Frontline chronic lymphocytic laeukemia, frontline/indolent non-Hodgkin’s lymphoma, relapsed refractory CLL
Chronic HBV infection
HIV/AIDS
HIV/AIDS
HIV/AIDS
Several types of cancer
Staphylococcus aureus Vaccine
Primary Insomnia
Rotavirus Vaccine
Ulcerative Colitis
Human papillomavirus
Treatment of Invasive Aspergillosis in Adults
Multivalent Human Papillomavirus (HPV) L1 Virus-Like Particle (VLP) Vaccine
Prevention of Clinically Significant Human Cytomegalovirus (CMV) Infection in Adult, CMV-Seropositive Allogeneic Hematopoietic Stem Cell Transplant Recipients
Alzheimer’s Disease
Adult Patients with Solid Tumor or Hematologic Malignancy
Autologous Hematopoietic Cell Transplants (HCTs)
Active Axial Spondyloarthritis
Acute Coronary Syndrome
Refractory Chronic Lymphocytic Leukemia (CLL)
PIP Study in hypogonadal hypogonadism in males
Chronic Hepatitis C
Chronic Hepatitis C Virus Infection
Advanced Melanoma
Recurrent or Progressive Metastatic Urothelial Cancer
Recurrent or metastatic head and neck cancer
PD-L1 Strong Metastatic Non-Small Cell Lung Cancer
Progressive Locally Advanced or Metastatic Carcinomas and Melanoma and Non-Small Cell Lung Cancer
Non-Small Cell Lung Cancer
Gastric
Metastatic Triple-Negative Breast Cancer (mTNBC)
Clostridium difficile Infection (MODIFY I)
Pediatric Patients Receiving Emetogenic Chemotherapy for the Prevention of Post-Operative Nausea and Vomiting
Coronary Heart Disease (CHD) or CHD Risk- Equivalent Disease
Advanced/Unresectable or Metastatic Urothelial Cancer
Osteoporotic Postmenopausal Women Treated With Vitamin D and Calcium
Treatment-Naïve HIV Infected Patients
Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV) Associated With Moderately Emetogenic Chemotherapy
Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV) Associated with Emetogenic Chemotherapy in Pediatric Patients
Type 2 Diabetes Mellitus in Pediatric Patients
Type 2 Diabetes Mellitus and Mild Renal Impairment in patients with Inadequate Glycemic Control on Metformin
HIV Infected Patients
Diabetes type 2
Diabetes type 1
Haemophilia B
Haemophilia A
Diabetes type 2 in paediatric population
Diabetes type 1 and type 2
Malignant neoplasm of bronchus and lung
Schizophrenia
Atherosclerosis
Diabetes Mellitus
Malignant melanoma of skin
Irritable bowel syndrome
Alzheimer’s disease
Diffuse non-Hodgkin’s lymphoma, unspecified
Follicular (nodular) non-Hodgkin’s lymphoma
Lymphoid leukaemia
Malignant neoplasms of lymphoid haematopoietic +
Malignant neoplasm of breast
Malignant neoplasm of stomach
Rheumatoid arthritis
Systemic lupus erythematosus
Malignant neoplasm of bladder
Malignant neoplasm of ovary
Lymphoid leukaemia
Dermatitis (Allergic Contact)
Other disorders involving the immune mechanism
Peripheral Vascular Diseases
Thyrotoxicosis (hyperthyroidism)
Malignant neoplasm of brain
Acute myocardial infarction
Atherosclerosis
Chronic viral haepatitis
Retinal disorders other
Other necrotizing vasculopathies
Pemphigus
Lymphoid leukaemia
Other + unspecif. types of non-Hodgkin’s lymphoma
Influenza
Diabetes Mellitus
Transplanted organ and tissue status (Excl. complications)
Malignant neoplasm of colon/rectum
Malignant neoplasms
Perianal fistula in Crohn disease patients
Knee Osteoarthritis
Rheumatoid Arthritis, Crohn Disease
Gastric cancer
Migraine
Various cancer types
Crohn´s disease
Giant cell tumour of the bone
Heart failure
Myelodysplastic syndromes
Lupus Nephritis
Multiple Sclerosis
Secondary Progressive Multiple Sclerosis
Optic Neuritis
Crohn’s disease
Respiratory syncytial virus
Ventricular tachycardia / Ventricular fibrillation
Pulmonary arterial hypertension
Ulcerative colitis
Solid tumors
Pancreatic cancer
Nonalcoholic steatohaepatitis
Liver fibrosis, primary sclerosing cholangitis, nonalcoholic steatohaepatitis
Idiopathic pulmonary fibrosis
Colorectal Cancer, Prostate cancer, solid tumours
Autoinmune disease
Active Rheumatoid Arthritis
Breast Cancer
Asymptomatic Chronic Chagas Disease
Pneumonia in Infants
Primary dysmenorrhea of vaginal rings
Type 2 Diabetes Mellitus and Inadequate Glycemic Control
Metastatic Rectal Cancers (mRC)
Diabetes type 1
Diabetes type 2
Malignant neoplasm of kidney except renal pelvis
Fragile X Syndrome
Cytomegaloviral disease
Malignant neoplasms
Lymphoid leukaemia
Malignant neoplasm of other and unspecified parts of biliary tract
Malignant neoplasm of liver
Viral agents as cause of diseases classified to other
Malignant neoplasm without specification of site
Malignant neoplasms
Malignant neoplasm of prostate
Other diseases of upper respiratory tract
Malignant neoplasm of brain
Malignant neoplasm of kidney except renal pelvis
Influenza
Malignant neoplasm of cervix uteri
Malignant neoplasm of other and ill-defined sites
Other disorders involving the immune mechanism
HIV disease unspecified
Malignant neoplasm of bladder
Anaemia in neoplastic disease
Follicular [nodular] non-Hodgkin’s lymphoma
Malignant neoplasm of pancreas
EGFR (Epidermal growth factor receptor)
Solid Tumors - PPMTM Pleiotropic Pathway Modi er
High Risk for Invasive Fungal Infections
Select Advanced Solid Tumors
Multiple Myeloma
Assays of Alzheimer’s Disease Biomarkers
Growth hormone deficiency
Haemophilia A and B
Malignant neoplasms
Malignant neoplasms
Malignant neoplasms
Other malignant neoplasms of skin
Crohn’s disease
Crohn’s disease
Malignant neoplasms
Malignant neoplasms
Malignant neoplasms
Malignant neoplasms
Malignant neoplasms
Malignant neoplasms
Malignant neoplasms
Crohn’s disease
Malignant neoplasms
Severe sepsis
TBD (Tick-borne diseases)
Phase I
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RESEARCH PLATFORMS
www.asebio.com
Spanish Bioindustry Association
ASEBIO, the Spanish Bioindustry Association, encompasses over 280 firms, associations, foundations, universities, technology and
research centers which carry out activities directly or indirectly related to biotechnology.
Around 550 companies research and develop products in the Spanish biotechnology sector.
The wide number of associates makes ASEBIO the most appropriate meeting platform to face up the challenges of developing the
biotechnology sector in Spain.
Amgen
Amgen
Amgen
Biogen Spain
Biogen Spain
Genzyme
Genzyme
Genzyme
Merck KGaA
Merck KGaA
Novo Nordisk Pharma
Novo Nordisk Pharma
Novo Nordisk Pharma
Novo Nordisk Pharma
AbbVie
AbbVie
AbbVie
AbbVie
AbbVie
Amgen
Amgen
Amgen
Amgen
Amgen
Amgen
Amgen
Amgen
Amgen
Biogen Spain
Celgene
Celgene
Celgene
Celgene
Celgene
Celgene
Celgene
Gilead Sciences
Gilead Sciences
Gilead Sciences
Gilead Sciences
Gilead Sciences
Gilead Sciences
Gilead Sciences
Merck KGaA
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
MSD
Novo Nordisk Pharma
Novo Nordisk Pharma
Novo Nordisk Pharma
Novo Nordisk Pharma
Novo Nordisk Pharma
Novo Nordisk Pharma
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
TiGenix
AbbVie
AbbVie
Amgen
Amgen
Amgen
Amgen
Amgen
Amgen
Amgen
Biogen Spain
Biogen Spain
Biogen Spain
Biogen Spain
Celgene
Gilead Sciences
Gilead Sciences
Gilead Sciences
Gilead Sciences
Gilead Sciences
Gilead Sciences
Gilead Sciences
Gilead Sciences
Gilead Sciences
Merck KGaA
Merck KGaA
MSD
MSD
MSD
MSD
MSD
MSD
MSD
Novo Nordisk Pharma
Novo Nordisk Pharma
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
TiGenix
AbbVie
Celgene
MSD
MSD
MSD
MSD
Novo Nordisk Pharma
Novo Nordisk Pharma
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
Roche
TiGenix
TiGenix
Company
3P BIOPHARMACEUTICALS
AC-Gen Reading Life
AC-Gen Reading Life
Bionaturis
BIOPOLIS
BIOPOLIS
BIOPOLIS
CIBER/CIBER-BBN
CIBER/CIBER-BBN
FUND. PROGRESO Y SALUD (BIONAND)
Gadea Biopharma
Health in Code
Histocell
Ingeniatrics Tecnologias
Intelligent Pharma
Iproteos
OWL Metabolomics
Plebiotic
SISTEMAS GENÓMICOS
SISTEMAS GENÓMICOS
StemTek Therapeutics
Vivia Biotech
Bionanoplus
BIOMOL-INFORMATICS
Bionanoplus
ASCIL Biopharm
ASCIL Biopharm
FUND. PROGRESO Y SALUD (IATA)
Fundacion MEDINA
Fundacion MEDINA
Fundacion MEDINA
Fundacion MEDINA
Fundacion MEDINA
Fundacion MEDINA
IRYCIS
Lipopharma Therapeutics
OPERON
PROTEOS Biotech
PROTEOS Biotech
ASCIL Biopharm
ASCIL Biopharm
ASCIL Biopharm
Bionanoplus
CIBER/CIBER-BBN
CIBER/CIBER-BBN
FUND. PROGRESO Y SALUD (OTT-SSPA-FISEVI/IBIS)(SAS)
Fundacion MEDINA
Ingeniatrics
Ingeniatrics Tecnologias
IMMUNOSTEP
Minoryx
Neuron Bio
Plebiotic
AC-Gen Reading Life
ASCIL Biopharm
ASCIL Biopharm
BIOPOLIS
BIOPOLIS
CIBER/CIBER-BBN
Enzymlogic
Enzymlogic
FUND. PROGRESO Y SALUD (CABIMER)
FUND. PROGRESO Y SALUD (CABIMER)
FUND. PROGRESO Y SALUD (BIONAND)
Fundacion MEDINA
IMEGEN
Inbiomed
Integromics
InKemia IUCT group
InKemia IUCT group
InKemia IUCT group
Leitat
Leitat
Leitat
Phyture Biotech
Plebiotic
Sagetis Biotech, S.L.
Type platforms
CRO / CMO
CRO / CMO
CRO / CMO
CRO / CMO
CRO / CMO
CRO / CMO
CRO / CMO
CRO / CMO
CRO / CMO
CRO / CMO
CRO / CMO
CRO / CMO
Screening
Screening
CRO / CMO
CRO / CMO
CRO / CMO
CRO / CMO / Screening
Enabling Technologies / CRO / CMO / Others
Enabling Technologies / CRO / CMO / Others
CRO / CMO
Screening
CRO / CMO
Drug Delivery
Enabling Technologies / Screening
Screening
Screening
Screening
Screening
Screening
CRO / CMO / Screening / Enabling Technologies
Drug Delivery
Screening
Drug Delivery
Enabling Technologies / Drug Delivery
CRO / CMO
CRO / CMO
CRO / CMO
Screening
CRO / CMO
CRO / CMO
Screening
Screening / Others
Enabling Technologies
Screening
CRO / CMO
CRO / CMO
Drug Delivery
Drug Delivery
Enabling Technologies / CRO / CMO / Screening
Enabling Technologies / CRO / CMO
Screening
Screening
Screening
Drug Delivery
Screening
Screening
Drug Delivery
Drug Delivery
CRO / CMO
Enabling Technologies / Others
Drug Delivery
Screening
Screening
Screening
CRO / CMO
CRO / CMO
CRO / CMO
CRO / CMO
Description
API/IMP release
Development of API formulation
Stability Studies (API/IMP/Cell banks)
GMP Cell Bank Manufacturing (MCB/WCB/EPCB) and storage
GMP production (fermenters up to 1000L and Bioreactors up to 400L) for Clinical trials and Commercial stage
Scale up and No GMP production for Preclinical studies
Analytics development and validation platform (API, IMP, IPC) for Biosimilars
Analytics development and validation platform (API, IMP, IPC) for New biological entities
Bioprocess Development/Optimisation Platform (USP/DSP)
Freedom-to-operate platform in Bacteria, yeast and mammalian
Production of advanced Therapy Medicinal Products
Biologics production: New Biological Entities (mAbs, vaccines, fusion proteins) and Biosimilars/Biobetters from microbial fermentation and mammalian cell culture
Phatogenomics
NGS, Sequence Capture; Genetic Diseases and Dysmorphic syndromes; Exome Analysis, Genomics, infections
Development and manufacturing of recombinant proteins by means of FLYLIFE technology
Contract manufacturing: upstream and downstream development, analytical development, scale-up
Metagenomics and metabolomic analysis
Preclinical validation platforms: C.elegans model for functional food, ingredients and drug trials
Production of Customized Biomaterials, Nanomaterials & Nanoconjugates
Production of Customized Biomolecules (Antibodies, Proteins and Peptides)
Genomics and Bioinformatic Platform of Andalusia / Nanoimaging & Metabolomic platform / Biobank
Industrial fermentation and downstream
Next Generation Sequencing by HiSeq 1500
Cell shipping medium. To develop ready-to-use cell based models for research
Process and technologies for customized Drug Delivery Formulations
Pythia, a technology for discovering the molecular polypharmacology
IPRO Technology is a platform for the discovery and development of peptidomimetics able to disrupt and/or modulate protein-protein or protein-ligand interactions
Lipidomics Platform
Molecular Dynamics product v2 (PleMD v2.0)
Whole exome resequencing in humans permits the identification of the new genes associated with both rare and common diseases
Pharmacogenomics. Markers of drug response
Drug screening / Discovery / validation on cancer stem cells, phenotypic HTS screening, secondary validation to in vivo efficacy testing
Cytometry Analysis for Personalized Medicine/Diagnosis/Pharma Profiling. Drug profiling and biomarker discovery collaborations
NANO-GES: drug delivery using polymeric encapsulation with esters of poly (methyl vinyl ether-co-maleic anhydride) PCT/EP2012/056900
Whole human exome sequencing: identification of new candidate genes for rare diseases
SANP: drug delivery using polimeric encapsulation with a vegetable hydrophobic protein PCT/EP2013/052795
ASRET Platform: Biomedical devices for implantable systems administration
ASMEX Platform: Safety syringes alternatives-prefilled ready to use medical devices for parenteral administration/syringes or cartridge
Maturing technological platform in advanced therapies: setting up and monitoring of clinical trials
Chemical Isolation & Structural Elucidation
Microbial and Mammalian cell culturing
Microbial Natural Product Libraries
Preclinical Safety Platform
Bioanalytical Platform
High throughput screening platform for drug discovery
miRNA platform to collaborate in the development and commercialization of new biomarkers for diagnosis, prognosis and drug response
A novel therapeutic approach: Membrane Lipid Therapy (MLT)
Opegen S.pneumoniae: Molecular test for the genotyping of Streptococcus pneumoniae infections
Culture and maintenance of bank cells under GMP conditions
Creation and qualification of cell banks: MCB and WCB
ASTECH Platform: Optimized presentation and technologies for freeze-dried drug product and formulation-prefilled system. Improvement of FD for injectables products
ASTIC Platform: Implantable biodegradable systems and medical devices for administration. From daily to semi-annual delivery of biologics or pharma drugs. Micro/nanoimplantable solid system.
ASMAT Platform: New semisolid Biodegradable biomaterials for controlled release applications
Antigen delivery for vaccines. Encapsulation of antigens with a polymer to increases the vaccination efficacy
Preclinical Validation-Bioimaging. Integrated Infrastructure on Production and characterization of Nanomaterials, Biomaterials and systems in Biomedicine
Preclinical Validation-Tissue, Biomaterial and Surface Characterization
Cell lines & Animal Models
High throughput screening platform for drug discovery
Platform for highthroughput analysis of microorganisms. Accelerated diagnosis of bacterial diseases. Several
Platform for coating of Medical Devices. Odontology
Reagents, columns and devices for Cell separation in Blood and Lymphatic systems
SEE-Tx: Site-directed Enzyme Enhancement Therapy
Drug discovery and development activities focused on neurodegenerative diseases, inflammatory processes and hypercholesterolemic conditions (HTS preclinical platform)
Novel software for molecular design of antibodies, based on molecular dynamics
Phatogenomis
ASLINX Platform: Parenteral controlled release liquid technology based on Inherent characteristics of the API
ASEM Platform: Parenteral controlled release technology built specifically around inherent characteristics of the API to get an optimal PK/PD with or without excipients
Novel functional probiotics screening, validation and production
Recombinant protein expression systems
High Performance Computing. Integrated Infrastructure on Production and characterization of Nanomaterials, Biomaterials and systems in Biomedicine
Development of an assay platform to perform binding kinetic profiling of GPCR agonist and antagonist in a HTS format
Development of proteins and assay platforms to screen for epigenetic drugs
Cancer Screening Cell lines & Animal Models
Hybridome/Antibody Production Platform
Liposome delivery System (Prostate Cancer)
Mass spectrometry metabolomics
Whole exome sequencing
iPSCs for Drug Screening
Genomics Analysis for Personalized Medicine/Diagnosis
Drug development platform: GMP Manufacturing of investigational drugs; Production of solid, semisolid and liquid (non-sterile) pharmaceutical products, Production of medicinal products under research and veterinary medicinal products, Support in studies for process validation
Drug development platform: Stability studies under ICH conditions (Product storage according to ICH regulations, Product testing, Development of study protocol, Preparation for the study report)
Drug development platform: Galenic development (Pre-formulation studies , Formulations development, Formulations Optimisation, Stability Formulations, Comparison of dissolution profiles, Batch Productions at pilot levels, Support in technological transfers)
In vivo animal model platform (oncology, efficacy, pre-tox, biodistribution, pre-pk)
In vitro cellular model platform (efficacy, pre-tox, MoA)
Monoclonal antibody generation & humanization
Development and manufacturing of recombinant proteins through the technology of plant cell cultures
Novel reverse docking software, for repositioning purposes
Delivery technologies for taking drugs across intestinal and ocular mucosa in oncology and other diseases
* Based on data provided by ASEBIO members. MAY 2015. ** Only coloured phases have been developed in Spain
www.asebio.com
R+D
Preliminary Clinical
Validation Validation Register
Ready to
Market
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Spanish Red Biotech Pipeline
*
Spanish Red Biotech Pipeline 2015
DRUGS: NATIONAL COMPANIES
D R U G S : NAT IONAL C OM P A NIES
31%
21%
Company
Product
Type of drug
Almirall
Bionanoplus
GP-PHARM
GP-PHARM
Stem Center S.L.U.
Venter Pharma S.L.
Almirall
FERRER
NATAC
PharmaMar
PharmaMar
PharmaMar
Reig Jofré
Almirall
Almirall
Archivel Farma
ESTEVE
ESTEVE
FERRER
FUND. PROGRESO Y SALUD / OTT (SAS)
FUND. PROGRESO Y SALUD / IATA (SAS)
GP-PHARM
PharmaMar
PharmaMar
PharmaMar
PharmaMar
PharmaMar
PRAXIS
SOM Biotech
SOM Biotech
Sylentis
Sylentis
Thrombotargets
Ability Pharmaceuticals
Araclon Biotech
Almirall
Coretherapix SLU (A Genetrix subsidiary)
ESTEVE
FERRER
Genmedica Therapeutics
GP-PHARM
GP-PHARM
GP-PHARM
GP-PHARM
GP-PHARM
Histocell
Histocell
Oryzon Genomics S.A.
PaloBiofarma
PaloBiofarma
PharmaMar
PharmaMar
Sanifit
Sanifit
VCN Biosciences
Ability Pharmaceuticals
Bioibérica S.A.
Bionaturis
Bioncotech Therapeutics
Bionure
DIOMUNE SL
EntreChem
EntreChem
EntreChem
EntreChem
ESTEVE
FECYT
FECYT
FECYT
FERRER
FIBROSTATIN
Formune SL
GP-PHARM
Histocell
MINORYX
Neuron Bio
nLife Therapeutics, S.L.
Oryzon Genomics S.A.
PaloBiofarma
PaloBiofarma
Pevesa
PRAXIS
PRAXIS
PRAXIS
ProRetina Therapeutics
PROTEOS Biotech
PROTEOS Biotech
PROTEOS Biotech
PROTEOS Biotech
Sylentis
TERACLON IDF
TERACLON IDF
Valentia Biopharma
Vivia Biotech
LAS 40464 (aclidinium bromide + formoterol)
Propylene Glycol Free Minoxidil Topical Formulation
Lutrate Depot 22,5 mg
Desmopresina Solution
GID SVF-1
LacTEST
LAS 41008
Ozenoxacin
Retriacyl
PM01183
Aplidin
Yondelis
Bioadhesive topical gel
LAS 41004
LAS 100977
RUTI®
E-52862
E-58425
Lorediplon
FIBAO-91 Melatonine Solution
Allogeneic Adipose Mesenchymal stem cells / Allodepleted Bone Marrow Progenitors
Engineered Corneas
Autologous Bone Marrow progenitors, Adipose and Bone Marrow Mesenchymal stem cells
Autologous Bone Marrow Mononuclear cells and Adipose Mesenchymal stem cells
Autologous Bone Marrow Mononuclear cells
FIMABIS-14003
Octeotride LAR
Aplidin
Aplidin
PM01183
PM01183
PM01183
EPIPROT
SOM3355
SOM0226
SYL1001
Bamosiran/SYL040012
TT-173
ABTL0812
ABvac40
LAS 190972
AlloCSC-01
HIVACAT
FAB-117
FIBAO-13014 Combination of Ketamine and Meperidine
FIBAO-116
Autologous Bone Marrow Mononuclear cells
GMC-252
Triptorelina Depot 1-3
Octeotride MAR
Lutrate Depot 45 mg
Pegylated Liposomes for Oncology
depot form.
HC016
HR004
Minerval
ORY-1001
PBF-509
PBF680
PM060184
PM01183
SNF472
SNF472
VCN-01
ABTL1014
BIS014
BNT-001
BO-110
BN201
IV1303
EC-8042 iv
EC-8105 iv
EC-70124 po
EC-70124 iv
Sanfilippo A syndrome:Vector AAV-sulfamidase gene
Pylori
p300
p38
FAB-114
FSSME12
EDA-HPVE7
FIMABIS-13001
FIMABIS-13007
FISEVI-14012
FISEVI-13007
FRM-5
FISEVI-13020
FISEVI 141
FISEVI-13002
FISEVI-121
FIBAO-13007
FIMABIS-99
FIMABIS-77
FIMABIS-13007
Risperidona Depot
HR017
LP226A1
MIN101
NST0037
NLF-PD-1233
ORY-2001
PBF-695
PBF-999
PEV pept. 01-02
TERFIQEC
Fibrodress
PROHEAL
PRO-001
Filgrastin G-CSF
IFN-beta 1b
IFN-alpha 2b
DUPUYGEL
SAG-001
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Gene / Cell Therapy
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Vaccines
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Gene / Cell Therapy
Gene / Cell Therapy
Gene / Cell Therapy
Gene / Cell Therapy
Gene / Cell Therapy
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Gene / Cell Therapy
Biodrugs / Drugs
Gene / Cell Therapy
Biodrugs / Drugs
Biodrugs / Drugs
Gene / Cell Therapy
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Gene / Cell Therapy
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Vaccines
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Gene / Cell Therapy
Gene / Cell Therapy
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Gene / Cell Therapy
Gene / Cell Therapy
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Gene / Cell Therapy
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
Biodrugs / Drugs
TRV-32-R
V1932
VLT 002
Vivia 009
17%
10%
8%
7%
7%
Aut
cer
Can
tem
sys
Me
Cen
tra
lN
erv
ous
olo
gy
s
ion
&E
ndo
crin
n
ect
tab
olic
ne
&I
Inf
atio
s
tem
nfla
mm
y
log
sys
tic
pha
oim
Lym
and
od
Blo
Op
mu
De
rm
ato
me
ry
s
em
pto
&o
gy
olo
alm
hth
and
circ
ula
tor
ys
yst
rom
ynd
Oth
ic s
rph
mo
Dys
vas
cul
ar
nd
sa
7%
Ge
net
Car
dio
ase
7%
6%
es
ers
6%
ise
Indication
DIAGNOSTICS AND PERSONALISED MEDICINE
Company
ic D
Non
Regulatory Regulatory
Phase I
Phase II
Phase III Registration Studies location
Preclinical Preclinical
<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<
Chronic obstructive pulmonary disease (COPD)
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<
Dermatology
Hair Loss
Europe
<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<
Cancer
Prostate Cancer
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<
Nocturnal Enuresis
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<
Others
Plastic and reconstructive surgery
Europe
<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<
Digestive System
Evaluation of hypolactasia
<<<<<<<<<<<<<<<<<<<<<<<<<
Psoriasis
Europe
<<<<<<<<<<<<<<<<<<<<<<<<<
Dermatology / Infections
Dermal infections
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Retinitis Pigmentosa
Europe
<<<<<<<<<<<<<<<<<<<<<<<<<
Cancer
Platinum-resistant ovarian cancer
Europe
<<<<<<<<<<<<<<<<<<<<<<<<<
Cancer
Multiple Myeloma
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Cancer
Soft Tissue Sarcoma related to Translocations
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Dermatology
Impetigo, skin infections
<<<<<<<<<<<<<<<<<<<<
Psoriasis
Europe
<<<<<<<<<<<<<<<<<<<<
Asthma & COPD
Worldwide
<<<<<<<<<<<<<<<<<<<<
Europe and South Africa
Infections
Active tuberculosis - Latent Tuberculosis
<<<<<<<<<<<<<<<<<<<<
Analgesia & Pain / Central Nervous System
Neuropathic Pain
Europe
<<<<<<<<<<<<<<<<<<<<
Analgesia & Pain
Pain treatment (CNS)
Europe
<<<<<<<<<<<<<<<<<<<<
Sleep disorders
Worldwide
<<<<<<<<<<<<<<<<<<<<
Infections
Sepsis
<<<<<<<<<<<<<<<<<<<<
Autoimmune & Inflammation / Blood and Lymphatic systems
Chronic Graft versus Host Disease, Haematological Malignancies
Europe
<<<<<<<<<<<<<<<<<<<<
Corneal ulcers
Europe
<<<<<<<<<<<<<<<<<<<<
Stroke, Multiple Sclerosis and ALS
Europe
<<<<<<<<<<<<<<<<<<<<
Digestive System
Extended Liver resection, Faecal Incontinence
Europe
Acute Myocardial Infarction/Dilated Myocardiopathy/Chronic Ischemic Cardiopathy/Critical Limb Ischemia in diabetic & non patients <<<<<<<<<<<<<<<<<<<<
Europe
<<<<<<<<<<<<<<<<<<<<
Dermatology / Infections
Treatment of mucocutaneous herpes infections
Europe
<<<<<<<<<<<<<<<<<<<<
Acromegaly
Worldwide
<<<<<<<<<<<<<<<<<<<<
Cancer
Multiple Myeloma in combination with bortezomid
Worldwide
<<<<<<<<<<<<<<<<<<<<
T cell Lymphoma
Worldwide
<<<<<<<<<<<<<<<<<<<<
Cancer
Combination trials
Worldwide
<<<<<<<<<<<<<<<<<<<<
Cancer
Lung cancer
Worldwide
<<<<<<<<<<<<<<<<<<<<
Cancer
Breast cancer
Worldwide
<<<<<<<<<<<<<<<<<<<<
Dermatology
Diabetic Foot
Europe
<<<<<<<<<<<<<<<<<<<<
Central Nervous System / Genetic Diseases and Dysmorphic syndromes
Huntington’s disease, Tourette syndrome and Tardive Dyskinesia
Europe
<<<<<<<<<<<<<<<<<<<<
Genetic Diseases and Dysmorphic syndromes / Central Nervous System
Transthyretin-related hereditary amyloidosis (Polyneuropathy, Cardiomyopathy and Senile Forms)
Europe
<<<<<<<<<<<<<<<<<<<<
Dry eye Syndrome
Europe
<<<<<<<<<<<<<<<<<<<<
Ocular Hypertension, Glaucoma
Europe and USA
<<<<<<<<<<<<<<<<<<<<
Haemorrhage
Europe
<<<<<<<<<<<<<<<
Cancer
Lung, Endometrial and Pancreatic Cancer
Europe
<<<<<<<<<<<<<<<
<<<<<<<<<<<<<<<
Chronic obstructive pulmonary disease (COPD)
Worldwide
<<<<<<<<<<<<<<<
AMI (Acute myocardial infarction)
Spain and Belgium
<<<<<<<<<<<<<<<
Infections
Prophylactic- Therapeutic HIV vaccine
Europe and USA
<<<<<<<<<<<<<<<
Spinal Cord Injury
Europe
<<<<<<<<<<<<<<<
Mucositis
<<<<<<<<<<<<<<<
Analgesia & Pain
Fibromyalgia
<<<<<<<<<<<<<<<
Critical Limb Ischemia in diabetic patients
Worldwide
<<<<<<<<<<<<<<<
Type 2 Diabetes
Europe
<<<<<<<<<<<<<<<
Europe and Latinamerica
Cancer
Prostate Cancer
<<<<<<<<<<<<<<<
Cancer / Digestive System
Acute diarrhoea post chemotherapy
Worldwide
<<<<<<<<<<<<<<<
Cancer
Prostate Cancer
Worldwide
<<<<<<<<<<<<<<<
Cancer
Advanced Ovarian Cancer, Advanced Breast Cancer
Worldwide
<<<<<<<<<<<<<<<
Cancer
Several
<<<<<<<<<<<<<<<
Neuroprotection & repair
Europe
<<<<<<<<<<<<<<<
Bone Regeneration
Europe
<<<<<<<<<<<<<<<
Cancer
Glioma and other solid tumours
Europe
<<<<<<<<<<<<<<<
Acute Myeloid Leukaemia, Solid tumors, Other oncohaematology indications
Europe
<<<<<<<<<<<<<<<
Cancer / Central Nervous System
Attention-Deficit, Hyperactivity Disorder (ADHD), Lung Cancer
<<<<<<<<<<<<<<<
Asthma
<<<<<<<<<<<<<<<
Cancer
Solid tumours
<<<<<<<<<<<<<<<
Acute leukaemia
Worldwide
<<<<<<<<<<<<<<<
Cardiovascular and circulatory systems / Metabolic & Endocrinology / Dermatology
Calciphylaxis (dialysis)
Europe
<<<<<<<<<<<<<<<
Cardiovascular disease (dialysis)
Europe
<<<<<<<<<<<<<<<
Cancer
Pancreatic cancer
Europe
<<<<<<<<<<
Leukaemia and Lymphomas
Europe
<<<<<<<<<<
Neuropathic pain
Europe
<<<<<<<<<<
Lysosomal storage diseases
<<<<<<<<<<
Cancer
Solid tumors
Europe
<<<<<<<<<<
Central Nervous System / Ophthalmology and optometry / Autoimmune & Inflammation
Acute Optic Neuritis, Neuromyelitis Optica, Multiple Sclerosis
Worldwide
<<<<<<<<<<
Infections
Sepsis treatment
Europe
<<<<<<<<<<
Cancer
Solid tumours
Europe
<<<<<<<<<<
Cancer
Ewing’s sarcoma
USA
<<<<<<<<<<
Cancer
Solid tumours
Europe
<<<<<<<<<<
Cancer
Solid and haematological tumours
Europe
<<<<<<<<<<
Lisosomal storage rare disease
<<<<<<<<<<
Infections
H. pylori
<<<<<<<<<<
Cancer
Cancer
<<<<<<<<<<
Neuropathic Pain
<<<<<<<<<<
Non Hodgkin Lymphoma
Europe
<<<<<<<<<<
Cancer
Lung and Breast Cancer
Europe
<<<<<<<<<<
Cancer
Cervical cancer
Europe
<<<<<<<<<<
Treatment and/or Prevention of Non-alcoholic fatty liver disease (NAFLD)
<<<<<<<<<<
Treatment and/or prevention of metabolic and cardiovascular diseases
<<<<<<<<<<
Infections
Multirresistant infections
Europe
<<<<<<<<<<
Cancer
Hepatocarcinoma
Europe
<<<<<<<<<<
Others
Transplant
Europe
<<<<<<<<<<
Europe
<<<<<<<<<<
Infections
Sepsis, Acute lung injury
Europe
<<<<<<<<<<
Cancer
Multiple myeloma
Europe
<<<<<<<<<<
Transplant
Europe
<<<<<<<<<<
Cancer
Cancer cells
Europe
<<<<<<<<<<
Nanoemulsions for the treatment of obesity
<<<<<<<<<<
Hydroxytyrosol ethers
<<<<<<<<<<
Treatment and/or Prevention of cardiovascular and metabolic diseases
<<<<<<<<<<
Schizophrenia
Worldwide
<<<<<<<<<<
Idiopathic Pulmonary Fibrosis
Europe
<<<<<<<<<<
Europe
<<<<<<<<<<
Genetic Diseases and Dysmorphic syndromes / Central Nervous System / Metabolic & Endocrinology Adrenoleukodystrophy
Europe
<<<<<<<<<<
Mild Cognitive Impairment / Epilepsy
Europe
<<<<<<<<<<
Parkinson Disease
Europe and USA
<<<<<<<<<<
Alzheimer’s disease, Parkinson’s disease, other dementias, Huntington’s disease, Rett’s syndrome
Spain
<<<<<<<<<<
Glaucoma
<<<<<<<<<<
Huntington Disease
<<<<<<<<<<
Metabolic Syndrome
Europe
<<<<<<<<<<
Cystic Fibrosis
Europe
<<<<<<<<<<
Dressing for Neuropathic bounds
Europe
<<<<<<<<<<
Dermatology
Bioactive wound dressings (Diabetic / vascular)
Europe
<<<<<<<<<<
Retinitis Pigmentosa
Europe
<<<<<<<<<<
Leukaemia
Europe
<<<<<<<<<<
Multiple Sclerosis
Europe
<<<<<<<<<<
Infections
Haepatitis C
Europe
<<<<<<<<<<
Dupuytren’s Contracture
Europe
<<<<<<<<<<
GBM (glioblastoma)
<<<<<<<<<<
Crohn’s disease and ulcerative colitis
Spain
<<<<<<<<<<
Glaucoma
Europe
<<<<<<<<<<
Diabetic Retinopathy
Europe
<<<<<<<<<<
Musculoskeletal Disorders / Genetic Diseases and Dysmorphic syndromes
Myotonic Dystrophy
Europe
<<<<<<<<<<
Blood and Lymphatic systems / Cancer / Central Nervous System
Non Hodgkin Lymphoma, CNS
Europe
Therapeutic areas
DI A GN O STI C S AND P E RS ONALIZ ED MEDIC INE
39%
16%
12%
12%
6%
7%
4%
Ge
Mu
scu
l
osk
Blo
Oth
e
Car
od
e
and letal D rs
dio
vas
net
i
L
so
ym
ic D cula
pha rders
r
ise
tic
ase and
sys
c
sa
tem
nd ircula
s
tor
Dys
ys
mo
rph yste
m
ic s
ynd s
r
o
D
Aut
me
s
oim igesti
ve
mu
s
ne
yst
em
&I
nfla
Cen
mm
tra
lN
erv ation
ous
sys
tem
Inf
ect
ion
s
Can
cer
3%
6%
13%
Product
Type
Therapeutic Area
www.asebio.com
Spanish Bioindustry Association
ASEBIO, the Spanish Bioindustry Association, encompasses over 280 firms, associations, foundations, universities, technology and
research centers which carry out activities directly or indirectly related to biotechnology.
The wide number of associates makes ASEBIO the most appropriate meeting platform to face up the challenges of developing the
biotechnology sector in Spain.
Around 550 companies research and develop products in the Spanish biotechnology sector.
AB-Biotics
Neuropharmagen
Biomarkers
AC-Gen Reading Life
HD-Gen test
Biomarkers / Diagnostic
AC-Gen Reading Life
MitoSeq
AC-Gen Reading Life
WMicroSeq
Others
AC-Gen Reading Life
PancSeq
AC-Gen Reading Life
OvaSeq
AC-Gen Reading Life
ColonSeq
AC-Gen Reading Life
BreastSeq
AC-Gen Reading Life
HC-Gen Test
Araclon Biotech
Kit ABtest
Biomarkers
BIOMOL-INFORMATICS
BIOMOL-EXOME
Diagnostic/Imaging
CYTOGNOS
Act-t4 Cell Kit
Biomarkers
FERRER
EPICUP (FAB-115)
Diagnostic
Fundación MEDINA
In vitro tests for toxicity, safety, ADME and plasma efficacy
Diagnostic/Imaging
GENETADI
FERTITEST
Diagnostic / Biomarkers
Gendiag
SudD inCde
Diagnostic
Gendiag
Cardio inCode
Diagnostic
Gendiag
Thrombo inCode
Diagnostic
Gendiag
Nutri inCode
Biomarkers
GENOMICA
CLART HPV4
Biomarkers
GENOMICA
CLART CMA EGFR
Biomarkers / Others
GENOMICA
CLART CMA NRAS·iKRAS
Biomarkers / Others
Health in Code
Genetic diagnosis of inherited cardiovascular diseases
Diagnostic
IMEGEN
Clinical exome
Diagnostic / Others
IMMUNOSTEP
ThromboStep
Diagnostic
IRYCIS
Biomarkers toidentify IFN-BETA drug response in multiple sclerosis Biomarkers / Diagnostic
LEITAT
Ready-to-use transport kits for xenobiotic interaction studies
Others
Life Length
Telomere Analysis Technology (TAT Test)
Myriad Genetics
Vectra® DA
Biomarkers
OPERON
Simple GDH
Oryzon
Cx-Bladder
Diagnostic/Imaging
OWL Metabolomics
OWLiver Care
Biomarkers
OWL Metabolomics
OWLiver Test
OWL Metabolomics
OWLSkin
Biomarkers
OWL Diagnostics
Owl Liver ® NAFLD
Diagnostic/Imaging
SECUGEN
GENOTYPING
Diagnostic/Imaging
SECUGEN
NEXT GEN SEQUENCING
Diagnostic/Imaging
SECUGEN
DNA SEQUENCING
Diagnostic/Imaging
Sistemas Genómicos
Oncopharma GeneProfile
Sistemas Genómicos
GeneSGKits
Diagnostic
Sistemas Genómicos
BabyTest Plus
Diagnostic
Sistemas Genómicos
DI GeneProfile
Sistemas Genómicos
Onco-GeneSGKits
Sistemas Genómicos
OSTEOGeneProfile®
Biomarkers
Sistemas Genómicos
MRisk®
Biomarkers
Sistemas Genómicos
NeuroGeneProfile®
Biomarkers
Sistemas Genómicos
OTOGeneProfile®
Biomarkers
Sistemas Genómicos
ONCOGeneProfile®
Biomarkers
Sistemas Genómicos
Inmutest®
Biomarkers
Sistemas Genómicos
Nuevo CardioGeneProfile®
Biomarkers
Sistemas Genómicos
MamaGeneProfile®
Biomarkers
VENTER PHARMA
LacTEST 2,7 powder for oral solution
Diagnostic
Vivia Biotech
Personalized Medicine Test in Haematological Malignancies
Biomedal
iVYLISA GIP
Others
IMMUNOSTEP
Infiltration in CNS
Diagnostic
Myriad Genetics
myRisk™
Diagnostic
Myriad Genetics
tumor BRACAnalysis CDx™
Myriad Genetics
EndoPredict®
Myriad Genetics
Prolaris®
Biomarkers / Others
PANGAEA BIOTECH
EGFR serum mutation test
Biomarkers
Progenika Biopharma
ID XT
Diagnostic
Progenika Biopharma
Proimplant
Biomarkers
ADVANCED MARKER DISCOVERY (Amadix)
Personalized Medicine
Biomarkers
Biomarkers
Biomarkers
Biocross
Multiparametric test
Biomarkers
Biokit S.A
BIO-FLASH® HIV-1+2 Ag/Ab
Diagnostic
Biokit S.A
BIO-FLASH® anti-HBe
Diagnostic
Biokit S.A
BIO-FLASH® HBe Ag
Diagnostic
Biokit S.A
BIO-FLASH® VZV IgG and IgM
Diagnostic
Biokit S.A
BIO-FLASH® Mumps IgG
Diagnostic
Biokit S.A
BIO-FLASH® Measles IgG
Diagnostic
Biokit S.A
BIO-FLASH® HSV 1+2 IgM
Diagnostic
Bioibérica S.A.
Osteotest
Diagnostic
CYTOGNOS
Diagnosis and MRD Euroflow tubes
FISEVI-62 Diagnotic Image Analisis tool
Diagnostic/Imaging
GENYO-1 Circultaing Biomarkers
Biomarkers
FIMABIS-80 Multiple Sclerosis Diagnostic Kit
Biomarkers
FISEVI-14017
Diagnostic/Imaging
FISEVI-14001
Biomarkers
FISEVI-13008
Biomarkers
FISEVI-133
Biomarkers
FIBAO-13039
Biomarkers
FISEVI-120
Diagnostic/Imaging
FISEVI-13004/13005
Biomarkers
GENDIAG
Point of Care Diagnosis
Biomarkers
GENETADI
TDARRAY
IMMUNOSTEP
Hemodilución (Bmplex)
Diagnostic
IRYCIS/F. Hospital Clínico San Carlos
Biomarkers immunotherapy treatment
IRYCIS
Noverl biomarkers of acute kidney injury based on miRNAs
Myriad Genetics
myPlan™ Renal Cancer
Myriad Genetics
myChoice™ HRD
Myriad Genetics
myPath™ Melanoma
Myriad Genetics
myPlan™ Lung Cancer
Diagnostic
OWL Diagnostics
Neurowlics EM
Diagnostic/Imaging
OWL Diagnostics
Owl Liver ® Fibrosis
Diagnostic/Imaging
OWL Diagnostics
Owl Liver ® ASH
Diagnostic/Imaging
PANGAEA BIOTECH
BRCA1 RNA test
Biomarkers
PANGAEA BIOTECH
EGFR enrichment test
Biomarkers
Progenika Biopharma
Promonitor
Patient monitoring equipment
Progenika Biopharma
Endometrix
Biomarkers
Sistemas Genómicos
EPILEPSY-GeneProfile
Vivia Biotech
Vivia Biotech
Vivia Biotech
ALTHIA
Patient monitoring equipment
ALTHIA
Biomarkers
APTUS Biotech
Apta-Leish
Diagnostic
BIOEF - Hospital Universitario Araba/BIOARABA
Predictor of good response in FEP
Biomarkers
BIOEF - H. Univ.Cruces/BIOCRUCES / UPV/EHU
Diagnosis and prognosis of melanoma
Biomarkers
BIOEF - H. Univ. Donostia/BIODONOSTIA
Predictor of PML
Biomarkers
Biokit S.A.
BIO-FLASH ® EBV
Diagnostic
Biokit S.A
HTLV Ab
Diagnostic
DIOMUNE SL
SEPSISpredict
ENTRECHEM
Bacterial biomarker of colon cancer
Biomarkers
FIMABIS-14007
Diagnostic/Imaging
FIMABIS-14005
Biomarkers
FIMABIS-94
Biomarkers
FIBICO-14008
Biomarkers
FIBAO-14007
Biomarkers
FISEVI-121
Others
GENYO-13001 / FIMABIS-13009
Biomarkers
FIBICO-45
Biomarkers
FIBAO-85 Acute Kidney Injury Diagnostic Kit
Biomarkers
FIBAO-92-93-122-130-141/FISEVI-124-125-133
IMMUNOSTEP
Disposable device for leukocyte separation
Diagnostic
Inbiomed
Melesona
Others
Inbiomed
Ubiquitin and SUMO traps
Biomarkers
Neuron Bio
MCI-AD Tool
Thrombotargets
Diagnosis sensor
Diagnostic
ALTHIA
ALTHIA
mAb for diagnosis and prognosis of brain tumors and lesions
APTUS Biotech
AptaDetect-HCV
Diagnostic
BIOEF - Hospital Universitario Donostia/BIODONOSTIA Genetic diagnostic based on pooled DNA
Diagnostic
Biokit S.A
BIO-FLASH ® HAV
Diagnostic
Biokit S.A
BIO-FLASH ® Parvovirus
Diagnostic
CYTOGNOS
Euroflow PID tubes
CYTOGNOS
Diagnosis flow cytometry kit
Diagnostic
CYTOGNOS
Diagnostic/Imaging
CYTOGNOS
Diagnostic
ENTRECHEM
Microbioma analysis
Biomarkers
FECYT
Diagnosis
Diagnostic/Imaging
FERRER
EPIBREAST (FAB-118)
Diagnostic
CABIMER-13002 Kit for hepatic fibrosis and cirrhosis diagnosis
Biomarkers
FIBICO-14009
Biomarkers
FIBICO-14025
Diagnostic
FIBICO-14001
Diagnostic
FIBAO-14010
Biomarkers
FIBAO-13004
Biomarkers
FIBAO-144/ 13019
Biomarkers
FIBAO-13004
Biomarkers
FIBAO-13038 / FIBICO-13007
Biomarkers
CABIMER-13001 Trombosis risk biomarker
Biomarkers
IMEGEN
NGS diagnostic Kits
Diagnostic / Others
Integromics
Genomics Analysis for Personalized Medicine/Diagnosis
Diagnostic / Imaging / Biomarkers
Leitat
ELISA kit to detect biomarker levels (S100A7)
Leitat
ELISA kit to detect biomarker levels (S100P)
Leitat
ELISA kit to detect biomarker levels (S100A4)
Leitat
Tailored-made formulations with nanoencapsulated active compounds Others
Leitat
Metabolic profile
Biomarkers
Leitat
In vitro cellular model for diagnosis
Biomarkers
Merck / Sysmex Inostics
Liquid Biopsy RAS Biomarker Testing
Neuron Bio
SLOS Tool
Biomarkers
OPERON
Simple Calprotectin
Diagnostic
OPERON
CT Oligogen
OPERON
MG Oligogen
OPERON
NG Oligogen
Oryzon
Early Diagnosis
Diagnostic/Imaging
Oryzon
Early Diagnosis
Diagnostic/Imaging
Pangaea Biotech
DX multiplex Non invasive
Diagnostic/Imaging
Treatment prediction system for advanced tumors
Diagnostic
POC system based on detection of circulating biomarkers
Preliminar Clinical
Ready to
Studies Location
Validation validation Register
Market
<<<<<<<<<<<<<<<<<<<<<<<<<
Pharmacogenetic test to identify the most suitable medication for each neuropsychiatric patient
<<<<<<<<<<<<<<<<<<<<<<<<<
NGS targeted panel for Hereditary Diseases Test
Spain
<<<<<<<<<<<<<<<<<<<<<<<<<
Whole Mitochondrial Sequencing
Spain
<<<<<<<<<<<<<<<<<<<<<<<<<
Whole Bacterial and Viral Genome Sequencing
Spain
<<<<<<<<<<<<<<<<<<<<<<<<<
Pancreatic cancer NGS genetic test
Spain
<<<<<<<<<<<<<<<<<<<<<<<<<
Ovarian and Breast Cancer NGS genetic test
Spain
<<<<<<<<<<<<<<<<<<<<<<<<<
Colon Cancer NGS genetic test
Spain
<<<<<<<<<<<<<<<<<<<<<<<<<
Breast Cancer NGS genetic test
Spain
<<<<<<<<<<<<<<<<<<<<<<<<<
Hereditary Cancer NGS genetic test
Spain
<<<<<<<<<<<<<<<<<<<<<<<<<
Alzheimer´s disease diagnostic kit in the early stages
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Genetic diagnostic (Human Exome)
Europe
<<<<<<<<<<<<<<<<<<<<<<<<<
Antibody kit for the identification and quantification by flow cytometry of activated CD4 T-cells
<<<<<<<<<<<<<<<<<<<<<<<<<
Cancer of Unkown Primary
Europe
<<<<<<<<<<<<<<<<<<<<<<<<<
Cytotoxicity, Neurotoxicity, Mitochondrial Toxicity, Cardiotoxicity, ADME tox
Spain
<<<<<<<<<<<<<<<<<<<<<<<<<
Genetic Diagnosis of Endometrial Infertility
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Genetic analysis of sudden cardiac death
<<<<<<<<<<<<<<<<<<<<<<<<<
Cardiovascular Risk Assessment
<<<<<<<<<<<<<<<<<<<<<<<<<
Detection of the 12 most relevant genetic variants associated to thrombosis
<<<<<<<<<<<<<<<<<<<<<<<<<
Customizing diet in overweight individuals with cardiovascular risk
<<<<<<<<<<<<<<<<<<<<<<<<<
Kit for detection and genotyping of 35 types of human papillomavirus (HPV)
Europe
<<<<<<<<<<<<<<<<<<<<<<<<<
Kit for detection of gene mutations involved in responses to anti-tumour therapy with monoclonal antibodies
Europe
<<<<<<<<<<<<<<<<<<<<<<<<<
Kit for detection of gene mutations involved in responses to anti-tumour therapy with monoclonal antibodies
Europe
<<<<<<<<<<<<<<<<<<<<<<<<<Europe, Mid. East, N. America, Latinam.
Cardiovascular Diseases
<<<<<<<<<<<<<<<<<<<<<<<<<
Exome sequencing clinically customized
<<<<<<<<<<<<<<<<<<<<<<<<<
Autoimmune Thrombocytopenia Diagnosis by flow cytometry
Europe
New patented method to identify good responders to Interferon beta (INF-beta) therapy in multiple sclerosis before treatment initiation<<<<<<<<<<<<<<<<<<<<<<<<<
Spain
<<<<<<<<<<<<<<<<<<<<<<<<<
To identify xenobiotic interactions for regulatory purposes
Europe
<<<<<<<<<<<<<<<<<<<<<<<<<
Age related diseases, Cancer, Cardiovascular, Degenerative diseases
Europe
<<<<<<<<<<<<<<<<<<<<<<<<<
Multi-biomarker blood test validated to measure Rheumatoid Arthritis
<<<<<<<<<<<<<<<<<<<<<<<<<
One-step immunochromatographic test for the qualitative detection of GDH from C. difficile in human faeces
<<<<<<<<<<<<<<<<<<<<<<<<<
Bladder Cancer
Spain and Portugal
<<<<<<<<<<<<<<<<<<<<<<<<<
Hepatic Diseases, Non-alcoholic fatty liver disease (NAFLD)
USA and Canada
<<<<<<<<<<<<<<<<<<<<<<<<<
Hepatic Diseases, Non-alcoholic fatty liver disease (NAFLD)
Europa and America
<<<<<<<<<<<<<<<<<<<<<<<<<
Dermatitis and other skin diseases
Europe
<<<<<<<<<<<<<<<<<<<<<<<<<
Non Alcoholic Fatty Liver Disease
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Genetic risk for Age related Macular Degeneration
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Genetic Diagnosis
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Genetic Diagnosis
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
136 genes established as biomarkers for the toxicity and response to the most common drugs in Oncology
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Kit for capture and sequencing of genes from DNA with CE
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
For pregnants
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Paediatrics
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Hereditary cancer
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Osteodisplasias and collagenopathies
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Melanoma
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Neurological diseases
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Hearing Impairment
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Oncology
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Food intolerance
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Cardiovascular Risk
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Breast Ovarian cancer
Worldwide
<<<<<<<<<<<<<<<<<<<<<<<<<
Subject with lactose intolerance
<<<<<<<<<<<<<<<<<<<<<<<<<
Acute Myeloid Leukaemia
Europe
<<<<<<<<<<<<<<<<<<<<
Monitoring of the gluten free diet in celiac patients
Spain
<<<<<<<<<<<<<<<<<<<<
Detection of Leptomeningeal disease
Worldwide
<<<<<<<<<<<<<<<<<<<<
Test for all hereditary cancer syndromes
Companion diagnostic tumor testing for mutations in BRCA1/2 genes indicated for patients with ovarian cancer treated with IPARP <<<<<<<<<<<<<<<<<<<<
<<<<<<<<<<<<<<<<<<<<
Breast cancer patients ER postive and HER2 negative
<<<<<<<<<<<<<<<<<<<<
Genetic test for prostate cancer
<<<<<<<<<<<<<<<<<<<<
Lung cancer, EGFR mutated
Worldwide
<<<<<<<<<<<<<<<<<<<<
Blood group genotyping
<<<<<<<<<<<<<<<<<<<<
Female infertility
<<<<<<<<<<<<<<<
Prostate cancer prognostic test
Spain
<<<<<<<<<<<<<<<
Colon Cancer prognostic and predictive test
Spain
<<<<<<<<<<<<<<<
Lung Cancer prognostic and predictive test
Spain
<<<<<<<<<<<<<<<
Colon Cancer: diagnostic test
Spain
<<<<<<<<<<<<<<<
Europe
<<<<<<<<<<<<<<<
HIV
<<<<<<<<<<<<<<<
Haepatitis B
<<<<<<<<<<<<<<<
Haepatitis B
<<<<<<<<<<<<<<<
Varicella
<<<<<<<<<<<<<<<
Mumps
<<<<<<<<<<<<<<<
Measles
<<<<<<<<<<<<<<<
Herpes 1 and Herpes 2
<<<<<<<<<<<<<<<
Osteoporosis
Europe
<<<<<<<<<<<<<<<
Multiple Myeloma patients by flow cytometry
Spain
<<<<<<<<<<<<<<<
Fibrosis / NASH (non-alcoholic steatohaepatitis)
Europe
<<<<<<<<<<<<<<<
Metastasis
Europe
<<<<<<<<<<<<<<<
Multiple sclerosis
<<<<<<<<<<<<<<<
Parkinson’s disease and other parkinsonims
Europe
<<<<<<<<<<<<<<<
Endometrial carcinoma
Europe
<<<<<<<<<<<<<<<
Colorectal cancer
Europe
<<<<<<<<<<<<<<<
Chronis obstructive respiratory disease / Lung cancer (adenocarcinoma)
Europe
<<<<<<<<<<<<<<<
Haepatitis C
Europe
<<<<<<<<<<<<<<<
Duchenne muscular dystrophy (DMD) and others
Europe
<<<<<<<<<<<<<<<
Haepatitis C
Europe
<<<<<<<<<<<<<<<
Fast diagnosis of stroke and its differentiation from stroke-mimicking conditions
<<<<<<<<<<<<<<<
Genetic Diagnosis of ADHD (Attention deficit hyperactivity disorder)
Worldwide
<<<<<<<<<<<<<<<
Detection of hemodilution in bone marrow samples
Worldwide
Biomarkers based on IgE profile for determining oral immunotherapy treatment response in children with cow’s milk protein allergy <<<<<<<<<<<<<<<
Spain
<<<<<<<<<<<<<<<
The identified panel of miRNAs can detect acute kidney injury (AKI) development before serum creatinine increases
Spain
<<<<<<<<<<<<<<<
Test Prognostics for renal cancer
Companion diagnostic test to identify metastatic breast cancer, ovarian and other tumors that may be sensitive to iPAPR and/or platinum <<<<<<<<<<<<<<<
Worldwide
<<<<<<<<<<<<<<<
Genetic profile to test pathogenic status of Melanoma biopsy
Worldwide
<<<<<<<<<<<<<<<
Lung Cancer prognostic test based on Cell Cycle Progression Genes
Worldwide
<<<<<<<<<<<<<<<
Multiple sclerosis prognosis
Europe
<<<<<<<<<<<<<<<
Liver Fibrosis
Europe
<<<<<<<<<<<<<<<
Alcoholic esteatohaepatitis
Europe
<<<<<<<<<<<<<<<
Solid tumours
Worldwide
<<<<<<<<<<<<<<<
Lung cancer, EGFR mutated
Worldwide
<<<<<<<<<<<<<<<
Monitoring of biologics
<<<<<<<<<<<<<<<
Non invasive diagnosis of endometriosis
<<<<<<<<<<<<<<<
Next-Generation Sequencing panel of 352 genes associated with epilepsy of family origin
Worldwide
<<<<<<<<<<<<<<<
Acute Lymphocytic Leukaemia
Europe
<<<<<<<<<<<<<<<
Chronic Lymphocytic Leukaemia
Europe
<<<<<<<<<<<<<<<
Multiple Myeloma
Europe
<<<<<<<<<<
Expert system for breast and colon cancer patient management
Spain
<<<<<<<<<<
Patient stratification in glioma
Spain
<<<<<<<<<<
Leishmaniasis
Spain
<<<<<<<<<<
Future good response to antipsychotic drugs in first-episode psychosis (FEP) disorders
<<<<<<<<<<
Diagnosis and Prognosis of melanoma
<<<<<<<<<<
Predictor of the risk of developing progressive multifocal leucoencephalopathy in natalizumab-treated multiple sclerosis patients
<<<<<<<<<<
Epstein-Barr Virus Infection
<<<<<<<<<<
Human T-lymphotropic virus infection
<<<<<<<<<<
Heart Infarction
Spain
<<<<<<<<<<
Colon cancer
<<<<<<<<<<
Allergic rhinitis
<<<<<<<<<<
Breast cancer
<<<<<<<<<<
Acute Lymphoblastic Laeukemia (ALL)
<<<<<<<<<<
Lung cancer screening
<<<<<<<<<<
Circulating stem cells
Europe
<<<<<<<<<<
Transplant
Europe
<<<<<<<<<<
Lupus erythematosus / Allergy
Europe
<<<<<<<<<<
Vascular Calcification
Europe
<<<<<<<<<<
Acute Renal Failure
Europe
<<<<<<<<<<
Adenocarcinome, Breast, Lung, Colorectal, Cervix tumours and Pancreas cancer / 5-FU treatment Prognosis
Europe
<<<<<<<<<<
Hematological malignancies
Spain
<<<<<<<<<<
Autoimmune pathologies and/or immunosupression treatments
<<<<<<<<<<
Cancer, Parkinson´s Disease & Alzheimer´s Disease
<<<<<<<<<<
Discriminatory diagnostic tool between Alzheimer´s disease and Mild cognitive impairment
Spain
<<<<<<<<<<
Alzheimer Disease
Europe
<<<<<
Patient stratification for difuse large b-cell lymphoma therapy
Spain
<<<<<
Glioblastoma, neurodegenerative disease
Spain
<<<<<
Haepatitis C Virus (HCV)
Spain
<<<<<
Genetic diagnostic based on pooled DNA
<<<<<
Haepatitis A
<<<<<
Parvovirus infection
<<<<<
Antibody kit for the diagnosis of immunodeficiencies by flow cytometry
Spain
<<<<<
Multiple Myeloma, Non-Hodgkin Lymphoma and Glioma
Europe
<<<<<
Diagnosis and follow-up of influenza, tuberculosis, haepatitis C and HIV
Australia and Europe
<<<<<
Diagnosis and follow-up of allergies (Type I Hypersensitivity)
Europe
<<<<<
Development of biomarkers (Microbioma)
<<<<<
Malaria
<<<<<
Breast Cancer
Europe
<<<<<
Hepatic Fibrosis and Cirrhosis
<<<<<
<<<<<
Haepatitis C
<<<<<
Hepatocarcinoma diagnosis
<<<<<
Meniere Disease
Europe
<<<<<
Colon Cancer
Europe
<<<<<
Meniere Disease
<<<<<
Colon Cancer
<<<<<
Cancer / Treatment of angiogenesis
<<<<<
Mesenchymal Stem Cells (MSCs)
<<<<<
Ready to use customized kits for using in NGS platforms
<<<<<
Diagnostics and Imaging / Screening
<<<<<
Several cancers
Spain
<<<<<
Pancreatic cancer, colon cancer, others
Spain
<<<<<
Pancreatic cancer, colon cancer, others
Spain
<<<<<
Atopic dermatitis, psoriasis
Spain
<<<<<
Helicobacter pylori infection, oxidative stress
Spain
<<<<<
Helicobacter pylori virulence
Spain
<<<<<
Metastatic colorectal cancer
Spain
<<<<<
Smith-Lemli-Opitz syndrome
Spain
<<<<<
One-step immunochromatographic test for the qualitative detection of Calprotectin in human faeces
<<<<<
Genetic test designed for the detection of Chlamydia trachomatis
<<<<<
Test designed for the detection of Mycoplasma genitalium
<<<<<
Test designed for the detection of Neisseria goorrhoeae
<<<<<
Parkinson Disease
Europe
<<<<<
Alzheimer Disease
Europe
<<<<<
Various tumours
Europe
<<<<<
Multiple cancers
Spain
<<<<<
Colon cancer
Spain and Germany
Indication
Cancer
Infections
Cancer
Cancer
Cancer
Cancer
Cancer
Autoimmune & Inflammation / Infections / Others
Cancer
Others
Women´s health
Cancer / Infections / Women´s health
Cancer
Cancer
Cardiovascular and circulatory systems / Genetic Diseases and Dysmorphic syndromes
Others
Cancer / Cardiovascular and circulatory systems
Digestive System / Infections
Cancer
Digestive System
Digestive System
Dermatology
Digestive System
Cancer
Several
Cancer
Cancer
Cancer
Cancer
Digestive System / Autoimmune & Inflammation
Digestive System / Autoimmune & Inflammation
Cancer
Cancer
Cancer
Cancer
Cancer
Cancer
Women´s health
Cancer
Cancer
Cancer
Cancer
Infections
Infections
Infections
Infections
Infections
Infections
Infections
Digestive System
Cancer
Cancer
Cancer
Cancer
Infections
Genetic Diseases and Dysmorphic syndromes / Musculoskeletal Disorders
Infections
Autoimmune & Inflammation / Others
Cancer
Cancer
Cancer
Cancer
Autoimmune & Inflammation / Digestive system
Autoimmune & Inflammation / Digestive system
Cancer
Cancer
Cancer
Cancer
Cancer
Infections
Cancer
Infections
Infections
Cardiovascular and circulatory systems / Infections
Cancer
Cancer
Cancer
Cancer
Cancer
Autoimmune & Inflammation / Blood and Lymphatic systems
Cancer
Infections
Infections
Infections
Cancer
Infections
Others
Infections
Cancer
Digestive System
Infections
Cancer
Cancer
Cancer
Cancer
Others
Cancer
Cancer
Cancer
Infections
Infections
Cancer / Digestive System
Genetic Diseases and Dysmorphic syndromes / Others
Digestive System
Infections
Infections
Infections
Cancer
Cancer
Cancer
R+D
OTHER TECHNOLOGIES
Company
Product
Type
Therapeutic areas
Indication
IRYCIS
IRYCIS/UC3M
Reig Jofré
Stem Center S.L.U.
Histocell
IRYCIS
BTI Biotechnology Institute
Histocell
IRYCIS
PROTEOS Biotech
GENYO-13002 Lentiviral Systems
Medical Device for alopecia monitoring
Biopsypunch
Blox Allergy
GID System
Reoxcare®
Smartphone-based platform for teledermatology
PRGF-Endoret Technology
GENYO-13007 MSCs Biomarker
GENYO-13006
FISEVI-140
HR007
Telemedicine platfroms
GENYO-13008
LARCEL-14001
CABIMER-13005 Culture Medium and Biomaterial
CABIMER-13004 Culture Medium
Collagenase
Others
Medical devices
Medical devices
Medical devices
Medical devices
Medical devices
Others
Biomaterials & Tissue Therapy
Others
Others
Others
Others
Others
Others
Others
Dermatology
Dermatology
Others
Dermatology
Dermatology
Others
Others
Dental
Dermatology
Cancer / Others
Others
Others
Dermatology
Insulator for improve gene expression
Medical device for a standarized monitoring of alopecia
New device for dermatological biopsies
Avoiding allergens
Plastic and reconstructive surgery
Wound healing
Communication channel between primary care physicians and dermatologists
Ophthalmology
Surface marker for MSCs
Multipotent Mesenchimal Stroma Cells Subpopulation
Resorbable membrane for guided bone regeneration
Tissular Regeneration
Comprehensive management of upper lymphedema after breast cancer, including its early detection, a practical-theoretical training and the possibility of contact with the specialist
Method for obtaining megakaryocytes and platelets
Method for generating Induced Pluripotent Stem Cells (iPSC)
Mesothelial cells in Tissue Bioengineering
Xeno-free culture and differentiation medium to convert hPSC to neural progenitors
Debridement of chronic dermal ulcers and severely burned areas
Advanced materials for repairing living tissues in bone and cartilage regeneration
R+D
* Based on data provided by ASEBIO members. MAY 2015. ** Only coloured phases have been developed in Spain
www.asebio.com
Preliminary Clinical
Validation Validation
Register
Ready
to Market
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Studies
Location
Spain
Spain
Spain
Europe
Spain
Europe
Europe
Spain
Europe

Spanish Red Biotech Pipeline*

Transcripción

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Spanish Red Biotech Pipeline*