Amoxicillin

Transcripción

Amoxicillin

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Amoxicillin
Sub-sections

Amoxicillin

Amoxicillin Sodium

Amoxicillin Trihydrate

Adverse Effects and Precautions

Interactions

Antimicrobial Action

Pharmacokinetics

Uses and Administration

Preparations
Amoxicillin
Date of monograph review: 26-Mar-1997; 21-Jul-1998; 16-Feb-2000; 12Sep-2001; 02-Sep-2003; 28-May-2004; 17-May-2005; 25-Jul-2006; 10Sep-2008; 17-Nov-2009; 20-Aug-2010; (latest modification: 30-Jan-2013)
Drug Nomenclature (Latest modification: 23-Sep-2011)
Synonyms: Αμοξυκιλλίνη; Amoksisilin; Amoksisilliini; Amoxicilina;
Amoxicillinum; Amoxycillin
BAN: Amoxicillin
INN: Amoxicillin [rINN (en)]
INN: Amoxicilina [rINN (es)]
INN: Amoxicilline [rINN (fr)]
INN: Amoxicillinum [rINN (la)]
INN: Амоксициллин [rINN (ru)]
INN: ‫[ أموك س ي س ي ل ين‬rINN (ar)]
INN: 阿莫西林 [rINN (cn)]
Chemical name: (6R)-6-[α-D-(4Hydroxyphenyl)glycylamino]penicillanic acid
Molecular formula: C16H19N3O5S =365.4
CAS: 26787-78-0
ATC code: J01CA04
ATC code (veterinary): QG51AX01; QJ01CA04
UNII code: 9EM05410Q9
Chemical Structure of Amoxicillin
Amoxicillin Sodium
Drug Nomenclature (Latest modification: 05-Dec-2011)
Synonyms: Amoksicilino natrio druska; Amoksisilin Sodyum;
Amoksisilliininatrium; Amoksycylina sodowa; Amoxicilin sodná sůl;
Amoxicilina sódica; Amoxicillin-Natrium; Amoxicillin-nátrium;
Amoxicilline sodique; Amoxicillinnatrium; Amoxicillinum Natricum;
Amoxycillin Sodium; BRL-2333AB-B; アモキシシリンナトリウム
BAN: Amoxicillin Sodium [BANM]
USAN: Amoxicillin Sodium
INN: Amoxicillin Sodium [rINNM (en)]
INN: Amoxicilina sódica [rINNM (es)]
INN: Amoxicilline Sodique [rINNM (fr)]
INN: Natrii Amoxicillinum [rINNM (la)]
INN: Натрий Амоксициллин [rINNM (ru)]
Molecular formula: C16H18N3NaO5S =387.4
CAS: 34642-77-8
ATC code: J01CA04
ATC code (veterinary): QJ01CA04
UNII code: 544Y3D6MYH
Pharmacopoeias:
In Chin. and Eur. (see
).
Ph. Eur. 7 (Amoxicillin Sodium). A white or almost white, very
hygroscopic powder. Very soluble in water; sparingly soluble in
dehydrated alcohol; very slightly soluble in acetone. A 10% solution in
water has a pH of 8.0 to 10.0. Store in airtight containers.
Amoxicillin Trihydrate
Drug Nomenclature (Latest modification: 30-Jan-2013)
Synonyms: Amoksicilinas trihidratas; Amoksisilin Trihidrat;
Amoksisilliinitrihydraatti; Amoksycylina trójwodna; Amoxicilin trihydrát;
Amoxicilina trihidrato; Amoxicillin-trihidrát; Amoxicillin-Trihydrat;
Amoxicilline trihydratée; Amoxicillintrihydrat; Amoxicillinum
Trihydricum; Amoxycillin Trihydrate; BRL-2333; アモキシシリン
BAN: Amoxicillin Trihydrate [BANM]
USAN: Amoxicillin
INN: Amoxicillin Trihydrate [rINNM (en)]
INN: Amoxicilina trihidrato [rINNM (es)]
INN: Amoxicilline Trihydratée [rINNM (fr)]
INN: Amoxicillinum Trihydricum [rINNM (la)]
INN: Амоксициллин Тригидрат [rINNM (ru)]
Molecular formula: C16H19N3O5S,3H2O =419.4
CAS: 61336-70-7
ATC code: J01CA04
ATC code (veterinary): QJ01CA04
UNII code: 804826J2HU
NOTE:
Compounded preparations of amoxicillin may be represented by the
following names:
Co-amoxiclav x/y (BAN)—amoxicillin (as the trihydrate or the sodium
salt) and potassium clavulanate; x and y are the strengths in
milligrams of amoxicillin and clavulanic acid respectively
Co-amoxiclav (PEN)—amoxicillin trihydrate and potassium clavulanate.
Pharmacopoeias:
In Chin., Eur. (see
), Int., Jpn, US, and Viet.
Ph. Eur. 7 (Amoxicillin Trihydrate). A white or almost white, crystalline
powder. Slightly soluble in water; very slightly soluble in alcohol;
practically insoluble in fatty oils. It dissolves in dilute acids and in dilute
solutions of alkali hydroxides. A 0.2% solution in water has a pH of 3.5
to 5.5. Store in airtight containers.
USP 36 (Amoxicillin). A white, practically odourless crystalline powder.
Slightly soluble in water and in methyl alcohol; insoluble in carbon
tetrachloride, in chloroform, and in benzene. pH of a 0.2% solution in
water is between 3.5 and 6.0. Store in airtight containers.
Adverse Effects and Precautions (Latest modification: 16-Sep-2009)
As for Ampicillin,
.
The incidence of diarrhoea is less with amoxicillin than ampicillin.
Hepatitis and cholestatic jaundice have been reported with amoxicillin plus
clavulanic acid (see
); the clavulanic acid component has been
implicated. Erythema multiforme, Stevens-Johnson syndrome, toxic
epidermal necrolysis, and exfoliative dermatitis have also been attributed
occasionally to the use of amoxicillin with clavulanic acid.
Use of amoxicillin with clavulanic acid during pregnancy for premature
rupture of the fetal membrane has been associated with an increased risk of
neonatal necrotising enterocolitis. For further information, see under
Premature Labour,
.
(last reviewed 2010-08-20; last modified 2009-09-16)
Breast feeding (Latest modification: 07-Aug-2010)
Although amoxicillin is excreted in breast milk in small amounts,1 the
American Academy of Pediatrics considers that it is usually compatible with
breast feeding.2
1. 1. Kafetzis DA, et al. Passage of cephalosporins and amoxicillin into the
breast milk. Acta Paediatr Scand 1981; 70: 285–8. PubMed
2. 2. American Academy of Pediatrics. The transfer of drugs and other
chemicals into human milk. Pediatrics 2001; 108: 776–89. PubMed
[Retired May 2010] Correction. ibid.; 1029. Also available at: online
(accessed 24/05/04)
Effects on the liver (Latest modification: 26-Jul-2010)
Hepatitis and cholestatic jaundice associated with the combination
amoxicillin with clavulanic acid (co-amoxiclav) have been reported1-4 and
by 1993 the UK CSM had received 138 reports of hepatobiliary disorders, 3
of which were fatal.5 It warned that, although usually reversible, the
reaction often occurred after stopping therapy with a delay of up to 6
weeks. It appeared that the clavulanic acid was probably responsible.
Retrospective analysis of cases reported in Australia6 and a cohort study in
the UK7 found increasing age and prolonged treatment to be major risk
factors for jaundice after co-amoxiclav; male sex is also a risk factor. By
1997 the CSM considered that cholestatic jaundice occurred with a
frequency of about 1 in 6000 adult patients and that the risk of acute liver
injury was about 6 times greater with co-amoxiclav than with amoxicillin
alone. Therefore it recommended that co-amoxiclav should be reserved for
bacterial infections likely to be caused by amoxicillin-resistant strains, and
that treatment should not usually exceed 14 days.8 Use is also considered
contra-indicated in patients with a history of jaundice or hepatic
dysfunction associated with co-amoxiclav or other penicillins.
1. 1. Stricker BHC, et al. Cholestatic hepatitis due to antibacterial
combination of amoxicillin and clavulanic acid (Augmentin). Dig Dis Sci
1989; 34: 1576–80. PubMed
2. 2. Wong FS, et al. Augmentin-induced jaundice. Med J Aust 1991; 154:
698–701. PubMed
3. 3. Larrey D, et al. Hepatitis associated with amoxycillin-clavulanic acid
combination report of 15 cases. Gut 1992; 33: 368–71. PubMed
4. 4. Hebbard GS, et al. Augmentin-induced jaundice with a fatal outcome.
Med J Aust 1992; 156: 285–6. PubMed
5. 5. CSM/MCA. Cholestatic jaundice with co-amoxiclav. Current Problems
1993; 19: 2. Also available at: online (accessed 28/07/08)
6. 6. Thomson JA, et al. Risk factors for the development of amoxycillinclavulanic acid associated jaundice. Med J Aust 1995; 162: 638–40.
PubMed
7. 7. Rodríguez LAG, et al. Risk of acute liver injury associated with the
combination of amoxicillin and clavulanic acid. Arch Intern Med 1996; 156:
1327–32. PubMed
8. 8. CSM/MCA. Revised indications for co-amoxiclav (Augmentin). Current
Problems 1997; 23: 8. Also available at: online (accessed 11/07/06)
Effects on the teeth (Latest modification: 07-Sep-2009)
Tooth discoloration associated with the use of amoxicillin with clavulanic
acid has been reported in 3 children.1
1. 1. Garcia-López M, et al. Amoxycillin-clavulanic acid-related tooth
discoloration in children. Pediatrics 2001; 108: 819–20. PubMed
Porphyria (Latest modification: 07-Nov-2011)
The Drug Database for Acute Porphyria, compiled by the Norwegian
Porphyria Centre (NAPOS) and the Porphyria Centre Sweden, classifies
amoxicillin and co-amoxiclav as not porphyrinogenic; they may be used as
drugs of first choice and no precautions are needed.1
1. 1. The Drug Database for Acute Porphyria. Available at: online (accessed
18/10/11)
Sodium content (Latest modification: 25-Mar-2004)
Each g of amoxicillin sodium contains about 2.6 mmol of sodium.
Interactions (Latest modification: 21-Mar-2000)
As for Ampicillin,
.
Antimicrobial Action (Latest modification: 18-Jul-2006)
As for Ampicillin,
.
Amoxicillin has been reported to be more active in vitro than ampicillin
against Enterococcus faecalis, Helicobacter pylori, and Salmonella spp., but
less active against Shigella spp.
Amoxicillin is inactivated by beta lactamases and complete cross-resistance
has been reported between amoxicillin and ampicillin. The spectrum of
activity of amoxicillin may be extended by use with a beta-lactamase
inhibitor such as clavulanic acid (
). As well as reversing resistance to
amoxicillin in beta-lactamase-producing strains of species otherwise
sensitive, clavulanic acid has also been reported to enhance the activity of
amoxicillin against several species not generally considered sensitive. These
have included Bacteroides, Legionella, and Nocardia spp., Haemophilus
influenzae, Moraxella catarrhalis (Branhamella catarrhalis), and Burkholderia
pseudomallei (Pseudomonas pseudomallei). However, Ps. aeruginosa,
Serratia marcescens, and many other Gram-negative bacteria remain
resistant. Transferable resistance has been reported in H. pylori.
Pharmacokinetics (Latest modification: 07-Sep-2009)
Amoxicillin is resistant to inactivation by gastric acid. It is more rapidly and
more completely absorbed than ampicillin when given orally. Peak plasmaamoxicillin concentrations of about 5 micrograms/mL have been seen 1 to 2
hours after a dose of 250 mg, with detectable amounts present for up to 8
hours. Doubling the dose can double the concentration. The presence of food
in the stomach does not appear to reduce the total amount absorbed.
Concentrations of amoxicillin after intramuscular injection are similar to
those achieved with oral doses.
About 20% is bound to plasma proteins and plasma half-lives of 1 to 1.5
hours have been reported. The half-life may be prolonged in neonates, the
elderly, and patients with renal impairment; in severe renal impairment the
half-life may be 7 to 20 hours. Amoxicillin is widely distributed at varying
concentrations in body tissues and fluids. It crosses the placenta; small
amounts are distributed into breast milk. Little amoxicillin passes into the
CSF unless the meninges are inflamed.
Amoxicillin is metabolised to a limited extent to penicilloic acid which is
excreted in the urine. About 60% of an oral dose of amoxicillin is excreted
unchanged in the urine in 6 hours by glomerular filtration and tubular
secretion. Urinary concentrations above 300 micrograms/mL have been
reported after a dose of 250 mg. Probenecid reduces renal excretion.
Amoxicillin is removed by haemodialysis. High concentrations have been
reported in bile; some may be excreted in the faeces.
Amoxicillin with clavulanic acid. The pharmacokinetics of amoxicillin and
clavulanic acid are broadly similar and neither appears to affect the other to
any great extent.
References.
1. 1. Sánchez Navarro A. New formulations of amoxicillin/clavulanic acid: a
pharmacokinetic and pharmacodynamic review. Clin Pharmacokinet 2005;
44: 1097–115. PubMed
Uses and Administration (Latest modification: 02-Sep-2010)
Amoxicillin is the 4-hydroxy analogue of ampicillin (
) and is used
similarly in susceptible infections. These include actinomycosis, anthrax,
biliary-tract infections, bronchitis, endocarditis (particularly for prophylaxis),
gastro-enteritis (including salmonella enteritis, but not shigellosis),
gonorrhoea, Lyme disease, mouth infections, otitis media, pneumonia,
spleen disorders (pneumococcal infection prophylaxis), typhoid and
paratyphoid fever, and urinary-tract infections. The beta-lactamase inhibitor
clavulanic acid (
) widens amoxicillin's antimicrobial spectrum and a
combined preparation (co-amoxiclav) can be used when resistance to
amoxicillin is prevalent, for example in respiratory-tract infections due to
Haemophilus influenzae or Moraxella catarrhalis (Branhamella catarrhalis), in
the empirical treatment of animal bites, or in melioidosis. For details of these
infections and their treatment, see under Choice of Antibacterial,
.
Amoxicillin is also given as part of treatment regimens to eradicate
Helicobacter pylori infection in patients with peptic ulcer disease (
).
Amoxicillin is given orally as the trihydrate and by injection as the sodium
salt. Doses are expressed in terms of the equivalent amount of amoxicillin;
1.06 g of amoxicillin sodium and 1.15 g of amoxicillin trihydrate are each
equivalent to about 1 g of amoxicillin.
The usual oral dose is 250 to 500 mg every 8 hours, or 500 to 875 mg every
12 hours. Higher oral doses of amoxicillin, either as a single dose or in short
courses, are used in some conditions. For example, a dose of 3 g repeated
once after 8 hours may be used for dental abscesses. A 3-g dose may be
given for uncomplicated acute urinary-tract infections, and repeated once
after 10 to 12 hours.
A high-dose regimen of 3 g twice daily may be used in patients with severe
or recurrent infections of the respiratory tract. Amoxicillin has also been
given as a single dose of 3 g, with probenecid 1 g, in the treatment of
uncomplicated gonorrhoea in areas where gonococci remain sensitive.
For the prophylaxis of endocarditis in patients at risk, amoxicillin 2 or 3 g
may be given about 1 hour before dental procedures. However, in the UK
the BNF 59 and NICE now suggest that such prophylaxis is unnecessary (see
).
For the eradication of H. pylori, amoxicillin is given with either metronidazole
or clarithromycin and a proton pump inhibitor; usual doses of amoxicillin are
0.75 or 1 g twice daily or 500 mg three times daily.
An extended release formulation containing 775 mg of amoxicillin as the
trihydrate is available in the USA for the treatment of tonsillitis and
pharyngitis due to Streptococcus pyogenes in patients aged 12 years or
older. It is given orally in a dose of 775 mg daily for 10 days.
Amoxicillin is given by intramuscular or slow intravenous injection in doses
of 500 mg every 8 hours. In severe infections, 1 g of amoxicillin may be
given every 6 hours by slow intravenous injection over 3 to 4 minutes or by
infusion over 30 to 60 minutes.
For details of doses in children, see
.
Doses may need to be reduced in moderate to severe renal impairment (see
).
Amoxicillin with clavulanic acid. Amoxicillin combined with clavulanic acid
(co-amoxiclav) is given orally in a ratio of amoxicillin (as the trihydrate) 2,
4, 7, or 14 parts to 1 part of clavulanic acid (as the potassium salt), or
intravenously in a ratio of 5 parts of amoxicillin (as the sodium salt) to 1
part of clavulanic acid (as the potassium salt). Doses of the combination,
calculated on amoxicillin content, are similar to those for amoxicillin used
alone.
References.
1. 1. Speller DCE, et al., eds. Clavulanate/β-lactam antibiotics: further
experience. J Antimicrob Chemother 1989; 24 (suppl B): 1–226.
2. 2. Todd PA, Benfield P. Amoxicillin/clavulanic acid: an update of its
antibacterial activity, pharmacokinetic properties and therapeutic use.
Drugs 1990; 39: 264–307. PubMed
3. 3. Malik ZA, Litman N. Ampicillin and amoxicillin. Pediatr Rev 2006; 27:
434–6. PubMed
4. 4. Geddes AM, et al. Introduction: historical perspective and development
of amoxicillin/clavulanate. Int J Antimicrob Agents 2007; 30 (suppl 2):
S109–S112. PubMed
5. 5. Ball P. The clinical development and launch of amoxicillin/clavulanate for
the treatment of a range of community-acquired infections. Int J
Antimicrob Agents 2007; 30 (suppl 2): S113–S117. PubMed
6. 6. Thanaviratananich S, et al. Once or twice daily versus three times daily
amoxicillin with or without clavulanate for the treatment of acute otitis
media. Available in The Cochrane Database of Systematic Reviews; Issue
4. Chichester: John Wiley; 2008 (accessed 06/08/09). PubMed
7. 7. Salvo F, et al. Amoxicillin and amoxicillin plus clavulanate: a safety
review. Expert Opin Drug Safety 2009; 8: 111–8. PubMed
Administration in children (Latest modification: 02-Sep-2010)
Amoxicillin may be given to neonates and children for the treatment of
infections caused by susceptible organisms, and for the prophylaxis of
endocarditis. It may be given orally, by intramuscular injection, by slow
intravenous injection over 3 to 4 minutes, or by intermittent intravenous
infusion over 30 to 60 minutes.
In the UK, licensed oral doses for children up to 10 years of age range
from 125 to 250 mg every 8 hours depending on the type and severity of
infection. For children 5 years and older, up to 500 mg every 8 hours has
been suggested by the BNFC 2009 for the treatment of severe infections
including uncomplicated community-acquired pneumonia, invasive
salmonellosis, and exacerbations of cystic fibrosis (7 years and older).
Additionally, the BNFC 2009 suggests the following oral dose range for
neonates and children up to 1 year of age:
neonates: 30 to 60 mg/kg, given every 12 hours for neonates less than
7 days of age and every 8 hours for those 7 to 28 days of age
children 1 month to 1 year of age: 62.5 to 125 mg 3 times daily
Licensed parenteral doses for children up to 10 years of age in the UK
range from 50 to 100 mg/kg daily in divided doses. The BNFC 2009 also
recommends the following intravenous dose ranges for neonates and
children:
neonates: 30 to 60 mg/kg, given every 12 hours for neonates less than
7 days old and every 8 hours for those 7 to 28 days of age. For
meningitis, 100 mg/kg per dose is recommended
children from 1 month of age: 20 to 60 mg/kg every 8 hours (to a
maximum of 4 g daily). For meningitis, group B streptococcal infection,
and endocarditis, 50 mg/kg every 4 to 6 hours (to a maximum of 2 g
every 4 hours) is recommended
In the USA, the following licensed oral doses are recommended for
amoxicillin depending on infection severity:
neonates and infants less than 12 weeks of age: a maximum of
30 mg/kg daily in divided doses every 12 hours
children from 3 months of age weighing less than 40 kg: 25 to 45 mg/kg
daily in divided doses every 12 hours, or 20 to 40 mg/kg in divided
doses every 8 hours
children from 3 months weighing 40 kg or more: as for adults (see Uses
and Administration,
)
Alternatively, for children from 1 month of age the American Academy of
Pediatrics (AAP)1 recommends oral doses of 25 to 50 mg/kg daily in 3
divided doses for most infections.
For otitis media, the BNFC 2009 recommends that children from 1 month
of age may be given oral amoxicillin 40 mg/kg (to a maximum of 3 g)
daily in 3 divided doses; alternatively the AAP recommends 90 mg/kg daily
in 2 divided doses. Where compliance may be a challenge, UK licensed
product information suggests an alternative course of 750 mg twice daily
for 2 days for children from 3 to 10 years of age.
For prophylaxis of endocarditis in children at risk, US experts2 suggest
a single oral dose of 50 mg/kg 30 to 60 minutes before high risk
procedures.
For doses in children with renal impairment see
.
1. 1. American Academy of Pediatrics. 2009 Red Book: Report of the
Committee on Infectious Diseases, 28th ed. Elk Grove Village, Illinois,
USA: American Academy of Pediatrics, 2009.
2. 2. Wilson W, et al. Prevention of infective endocarditis: guidelines from the
American Heart Association: a guideline from the American Heart
Association Rheumatic Fever, Endocarditis, and Kawasaki Disease
Committee, Council on Cardiovascular Disease in the Young, and the
Council on Clinical Cardiology, Council on Cardiovascular Surgery and
Anesthesia, and the Quality of Care and Outcomes Research
Interdisciplinary Working Group. Circulation 2007; 116: 1736–54. PubMed
Correction. ibid.; e376–7. Also available at: online (accessed 13/08/09)
Administration in renal impairment (Latest modification: 16-Nov-2009)
Oral doses of amoxicillin should be reduced in patients with moderate to
severe renal impairment according to creatinine clearance (CC):
CC 10 to 30 mL/minute: maximum 500 mg every 12 hours
CC less than 10 mL/minute: maximum 500 mg every 24 hours
haemodialysis patients: 250 to 500 mg every 24 hours and an additional
dose both during and after the dialysis session.
In children weighing less than 40 kg and up to 10 years of age with renal
impairment, UK licensed product information recommends dosage as
follows:
CC 10 to 30 mL/minute: 15 mg/kg (maximum 500 mg) every 12 hours
CC less than 10 mL/minute: 15 mg/kg (maximum 500 mg) once daily
Dose reduction should also be considered when giving amoxicillin by
parenteral routes.
Preparations (Latest modification: 04-Jul-2013)
Single-ingredient Preparations (Latest modification: 04-Jul-2013)
The symbol ¤ denotes a preparation which is discontinued or no longer
actively marketed.
Argentina: Abiotyl; Abramox¤; Almorsan; Amixen Duo; Amixen; Amox-G;
Amoxi Duo; Amoxi; Amoxibiot¤; Amoxicilina Duo¤; Amoxicina; Amoxicler;
Amoxidal Duo; Amoxidal; Amoxigrand; Amoxipenil; Amoxipoten¤;
Amoxitenk; Amoxol Duo; Amoxol; Antiamox¤; Antibiocilina¤;
Antiobiocilina¤; Apracur Biotic¤; Ardine¤; Atrival¤; Biotamoxal¤; Bioxilina
Duo; Bioxilina; Clofamox; Darzitil; Dunox; Fabamox; Flemoxon; Fullcilina
Duo¤; Fullcilina¤; Grinsil Duo; Grinsil; Mixcilin¤; Moxitral; Nobactam;
Optamox; Oximar¤; Plamox¤; Telmox; Trifamox Duo; Trifamox; Xalotina¤;
Australia: Alphamox; Amohexal¤; Amoxil; Ampexin¤; Bgramin; Cilamox;
Fisamox; Ibiamox; Maxamox; Moxacin¤; Moxiclav; Ranmoxy; Austria:
Amoxal¤; Amoxid¤; Amoxihexal; Amoxilan; Amoxistad; Antibiostad¤;
Clamoxyl; Eramox¤; Gonoform¤; Ospamox; Supramox¤; Belgium: Amoxi¤;
Amoxycaps¤; Amoxypen; Bactimed; Clamoxyl; Docamoxici¤; Flemoxin;
Hiconcil¤; Moxaline¤; Moxitop¤; Novabritine¤; Brazil: Amoflux¤; Amox;
Amoxadene; Amoxi-Ped; Amoxibron¤; Amoxicap¤; Amoxicom¤; Amoxidil;
Amoxifar¤; Amoxil; Amoximed; Amoxina; Amoxipen¤; Amoxitan; Amplal¤;
Amplamox¤; Ariproxina¤; Bimoxin¤; Camoxin¤; Cibramicina¤; Ductocilina;
Duzimicin¤; Farmoxil¤; Flemoxon¤; Hiconcil; Hincomox; Ibamoxil¤; Licilon;
Lifamox¤; Moxiplus; Nemoxil¤; Neo Moxicilin¤; Neo Moxilin; Novacil¤;
Novocilin; Novoxil¤; Ocylin; Penvicilin¤; Pharmox; Polibac¤; Polimoxil;
Probenil¤; Prodoxil¤; Respicilin¤; Sinot; Trimox; Ultramox; Uni Amox;
Velamox; Canada: Amox; Amoxil¤; Apo-Amoxi; Lin-Amox¤; Novamoxin;
Nu-Amoxi; Pro Amox; Chile: Abiolex; Amobiotic; Amoval Duo; Amoval;
Amoxipenil; Moxilanic; Optamox; China: A Lin Xin; Akelin; Amoling¤;
Amoxian¤; Amoxilin; Amoxy; Hypher; Qingdi; Ri Ao; Xindabeining; Yabao
Like; Yi Sa Lin; Zai Lin; Czech Republic: Amoclen¤; Amogal¤; Amoxihexal;
Apo-Amoxi¤; Duomox; Gonoform¤; Grunamox¤; InfectoMox¤; Ospamox;
Denmark: Flemoxin; Imacillin; Imadrax; Finland: Amorion; Amoxin;
Clamox¤; Flemoxin¤; Penalta¤; France: A-Gram¤; Amodex; Amophar¤;
Amoxine¤; Bactox; Bristamox¤; Clamoxyl; Flemoxine¤; Gramidil¤;
Hiconcil¤; Zamocilline¤; Germany: Aloxyn¤; Amagesan¤; Amc-Puren¤;
amoxi-basan¤; Amoxi-Diolan¤; Amoxi-Hefa; Amoxi-Puren¤; Amoxi-saar;
Amoxi-Tablinen; Amoxi-Wolff¤; Amoxi-Wolff; Amoxi; Amoxibeta;
Amoxibiocin¤; Amoxidoc¤; Amoxihexal; Amoxillat¤; Amoximerck¤;
Amoxypen¤; Baktocillin; Clamoxyl¤; Cuxacillin¤; Dignoamoxicillin¤; dura
AX¤; espa-moxin¤; Flui-Amoxicillin¤; Glassatan¤; InfectoMox; Jephoxin¤;
Jutamox¤; Padiamox¤; Phamoxi¤; Sigamopen¤; Ulcolind Amoxi¤; Uro-
Clamoxyl¤; Greece: Amospes; Amoxil; Amoximycin; Aproxal; Bimoxal;
Chromoxyl; Daminopen; Dipenocin; Drinus; Flemoxin; Geymocillina; Izoltil;
Lamberin; Matasedrin; Ospamox; Paradroxil; Prevasal; Princimox;
Selevistine; Stevencillin; Surmagal; Triodanin; Wesfem; Hong Kong:
Amolin¤; Amon¤; Amox¤; Amoxa¤; Amoxapen; Amoxil¤; Amoxon¤;
Amoxy¤; Apo-Amoxi¤; Aroxin; Betamox¤; Edamox; Hamoxillin¤; Hiconcil¤;
Moxcillin¤; Moxcin¤; Moxen¤; Moxilen; Moxipen¤; Moxlin; Ospamox;
Promox; Ranoxyl¤; Reichamox¤; Setmoxil¤; Unimox; Hungary: Clonamox;
Duomox; Humamoxin¤; Ospamox; India: Actimox; Allmox; Amosym;
Amox; Amoxil; Amoxinga; Amoxipen; Amoxivan; Amoxybid; Amoxyn;
Amoxypen; Amyn; Antimox; Apimox; Aristomox; Atmox; Axcel; Axl;
Betacillin; Betmox; Big Mox; Biomoxil; Bitamox; Blismox; Blumox; Brimox;
Cidomex; Cipmox; Clearmox; Damoxy; Delamin; Dicimox; Dormox;
Dynamox; E-Amox; Edomox; Erox P; Erox; Euphomox; Finemox; Flemoxin;
Fydomox; Genmox; Glamoxin; Glymox; Gutenmox; Hipen; Hycimox;
Idimox; Imox; Inmox; Jetmox; Kemox; Labmox; Lakmox; Lamoxy; Lexmox;
Linmox; Lomox; Loxyn; Lupimox; Magcil; Max; Maxmox; Mokcan;
Monamox; Mopen; Mormox; Mox; Moxi; Moxibact; Moxidat Kid; Moxiday;
Moxileb; Moxilup; Moximet; Moximon; Moxind; Moxinova; Moxinta; Moxipal;
Moxipil; Moxiplus; Moxitrac; Moxspen; Moxtid; Moxybiotic; Moxycarb;
Moxydil; Moxylong; Moxystat; Natamox; Nepomox; Novamox; O-Moxy;
Octamox; Olymox; Onamox; Optimox; Osomox; Ronemox; Symoxyl;
Indonesia: Abdimox¤; Aclam; Amobiotic; Amosine; Amoxil; Amoxillin;
Amoxsan; Arcamox; Bellacid; Bintamox¤; Bioxyllin¤; Bufamoxy; Corsamox;
Danoxilin; Dexymox; Erphamoxy; Ethimox; Farmoxyl; Ikamoxyl; Intermoxil;
Kalmoxillin; Kimoxil; Lactamox; Lapimox; Leomoxyl; Medimox¤; Medocyl¤;
Mestamox; Mexylin; Mokbios; Moxlin¤; Moxtid¤; Novax; Nufamox; Opimox;
Ospamox; Pehamoxil; Penmox; Primoxil¤; Pritamox; Rindomox; Robamox;
Scannoxyl; Silamox¤; Solpenox; Supramox; Topcillin; Vibramox; Wiamox;
Widecillin; Xiltrop; Ireland: Almodan¤; Amoxil; Clonamox; Galenamox¤;
Geramox; Hiconcil¤; Oramox; Pinamox; Rimoxallin¤; Roxillin¤; Israel:
Amoxi; Apomoxyn¤; Hiconcil¤; Moxypen; Moxyvit; Italy: Alfamox; AM 73¤;
Amocrin¤; Amoflux; Amosol; Amox; Amoxibiotic¤; Amoxillin¤; Amoxina;
Amoxipen¤; Aspenil¤; Bradimox¤; Cabermox¤; Dodemox¤; Erremox¤;
Genimox¤; Helimox¤; Hydramox; Ibiamox¤; Isimoxin¤; Majorpen¤; Mopen;
Moxiren¤; Neo-Ampiplus¤; Neotetranase; Oralmox; Pamocil; Piramox¤;
Posmox; Progemox¤; Sievert; Simoxil¤; Simplamox¤; Sintopen; Velamox;
Zamocillin¤; Zimox; Japan: Pasetocin; Malaysia: Beamoxy; Betamox;
Moxacil¤; Moxilen; Moxipen¤; Ospamox; Setmoxil¤; Mexico: Acimox;
Acroxil; Ameclina¤; Amicil; Amobay; Amoxifur; Amoxil; Amoxinovag¤;
Amoxisol; Amoxivet; Ampliron; Amsaxilina; AMX¤; Ardine¤; Armoxin;
Axcil¤; Betabiot; Bimoxan¤; Biotaxil; Biovicam; Brenoxil; Deniren¤;
Dimopen; Doxamil; Examolin; Flemoxon; Gimalxina; Grunicina¤; Hidramox;
Limoxin; Lorexil M; Lumox; Micro Mox; Micromox; Mocimed; Moxicel¤;
Moxiclina; Moxlin; Penamox; Penticlox; Polymox; Prodomix; Servamox-F;
Servamox; Solciclina; Vandix¤; Xalyn-Or; Xiprocan¤; Netherlands:
Amoxi¤; Amoxilag¤; Clamoxyl¤; Flemoxin; Hiconcil¤; Norway: Amimox¤;
Amoxillin; Imacillin; New Zealand: Alpha-Amoxi; Alphamox; Amoxi;
Amoxil; Apo-Amoxi; Flemoxin; Ibiamox; Moxlin¤; Ospamox; Penamox¤;
Philippines: Agpen; Amelox; Amoxico; Amoxil; Amusa¤; AMX; Ardent;
Axmel; Bactigent; Benemox; Bradoxil; Cartrimox; Cilamox; Cilfam;
Clearamox; Cycamil; Daisamox; Eleomox; Eppitrexil; Essenmox¤; Gexcil;
Globamox; Globapen; Harbimox; Himox; Koact; Kramollex; Lewixin;
Littmox; Maelenoxyl; Maroxil; Medimoxil; Medvox; Megamox; Moks;
Montramox¤; Moxillin; Moxiped¤; Neomox; Novamox; Pediamox; Pediaxil;
Penbiosyn; Pharmamox; Promox; Roddexil; Sterimox; Sumoxil; Syncloxil;
Taimox; Telsimox; Teramoxyl; Termox; Trexil; Valmox¤; Valzimox;
Vastamox; Vaxman¤; Vhellox; Westfimox; Xazexy¤; Xybatron; Yugoxil;
Zedroxyn; Zerrsox; Zymoxyl; Poland: Amotaks; Apo-Amoxi¤; Duomox;
Grunamox¤; Hiconcil; Novamox; Ospamox; Portugal: Amoxil; Amplamox;
Bodisan¤; Cipamox; Clamoxyl; Flemoxin; Moxadent; Moxipen¤; Oraminax;
Ospamox; Penamox¤; Russia: Amosin (Амосин); Flemoxin (Флемоксин);
Gramox (Грамокс); Hiconcil (Хиконцил); Ospamox (Оспамокс); Ranoxyl
(Раноксил); South Africa: A-Lennon¤; Acucil¤; Allmox; Amocas; Amocillin;
Amoxicap; Amoxil; Amoxyfizz¤; AMX¤; Arcanacillin¤; Betamox; C-Mox¤;
Ibiamox¤; Ipcamox; Maxcil¤; Moxan; Moxymax; Moxypen; Mymox;
Norimox¤; Penmox¤; Pharmoxin¤; Polymox¤; Promoxil; Ranmoxy; Rocillin¤;
Saltermox; Spectramox; Ultramox¤; Unimox¤; Xeracil¤; Xillin¤; Yomax;
Zaloxy; Zoxil; Singapore: Amoxa; Amoxapen; Amoxicap; Amoxigran;
Amoxil; Amoxitab¤; Apo-Amoxi; Aroxin; Betamox; Moxilen; Moxipen;
Ospamox; Pulmoxy; Ranoxyl¤; Strimox; Synamox; Unimox; Spain:
Actimoxi¤; Acuotricina¤; Agerpen¤; Amitron¤; Amoflamisan¤; Amox¤;
Amoxaren; Amoxi Gobens; Amoxibacter¤; Amoxidel¤; Amoximedical¤;
Amoxipen¤; Amoxyvinco¤; Apamox; Ardine¤; Axibiot¤; Becabil¤; Bimoxi¤;
Bioxidona¤; Blenox¤; Bolchipen¤; Borbalan¤; Britamox; Brondix¤;
Cidanamox¤; Clamoxyl; Co Amoxin¤; Combitora¤; Dacala¤; Damoxicil¤;
Diacibrone¤; Dobriciclin¤; Edoxil¤; Eupen¤; Flubiotic¤; Hortepulmo Antibio¤;
Hosboral; Inexbron¤; Maxiampil¤; Mediamox¤; Metifarma¤; Morgenxil¤;
Moxipin¤; Novagcilina¤; Olmopen¤; Precopen¤; Raudopen¤; Recefril¤;
Reloxyl¤; Remisan¤; Riotapen¤; Salvapen¤; Suamoxil¤; Superpeni¤;
Teramox¤; Tolodina¤; Wassermox¤; Sweden: Amimox; Amoxiferm¤;
Bristamox¤; Flemoxin¤; Imacillin; Switzerland: amoxi-basan¤; AmoxiCophar¤; Amoxi-Mepha; Amoximex¤; Antiotic¤; Azilline; Clamoxyl;
Escamox¤; Flemoxin¤; Helvamox¤; Penimox¤; Pharmamox¤; Rivoxicillin¤;
Servamox¤; Sigamopen¤; Spectroxyl¤; Supramox¤; Thailand: Acticillin;
Amacin; Amox; Amoxa¤; Amoxcillin; Amoxi; Amoxidon; Amoxil; Amoxin;
Amoxlin; Amoxy; Amoxylin¤; Amoxypac; Asiamox; Augxil-G; Biomox¤;
Bomox; Camox; Clanoxy; Coamox; Dymoxin; Ibiamox; Kamoxin¤; KenyaMox¤; Manmox; Meixil; Milamox; Mox; Moxapen¤; Moxcil; Moxcillin; Moxcin;
Moxilcap; Moxilen¤; Moxilin; Moximed; Moxipan¤; Moxitab¤; Moxno¤;
Moxodyl; Moxxo¤; Moxycillin; Moxyno; Moxypac; Pondnoxcill; Posmox¤;
Promoxy; Pulmoxyl¤; Pyramox; Rancil; Ranoxyl; Rapiclav; Samox;
Samoxil¤; Samoxin; Sanomox; Servamox; Sia-Mox; Sil-A-Mox¤; Sumoxcin;
TO Cillin; TV Mox; U-Amox; Unimox; Turkey: Alfoxil; Amoksilav; Amoksilin;
Amoksina; Amosin; Atoksilin; Bioksil; Demoksil; Largopen; Moksilin;
Neoamox; Remoxil; Topramoxin; Trimosin; Xibac; United Arab Emirates:
Julphamox; United Kingdom: Almodan¤; Amix¤; Amopen¤; Amoram;
Amoxident; Amoxidin¤; Amoxil; Amoxymed¤; Amrit¤; Flemoxin¤;
Galenamox; Rimoxallin; Ukraine: Amoxil (Амоксил-КМП); Flemoxin
(Флемоксин); Gramox (Грамокс); Hiconcil (Хиконцил); Ospamox
(Оспамокс); United States: Amoxil; Biomox¤; DisperMox; Larotid¤;
Moxatag; Polymox¤; Trimox; Wymox¤; Venezuela: Amitrexyl; Amofar;
Amoxal; Amoxiduo; Amoxiga; Amoxilan; Amoxipen¤; Amoxival; Amylin;
Bactamox¤; Fibramox¤; Flemoxon¤; Ofamix¤; Ospamox; Sentapen;
Strimox; Sumopen; Trimoxal;
Multi-ingredient Preparations (Latest modification: 01-Jul-2013)
The symbol ¤ denotes a preparation which is discontinued or no longer
actively marketed.
Argentina: Acemuk Biotic; Aclav¤; Albesine Biotic; Amixen Clavulanico;
Amixen Plus; Amoclav Duo; Amoclav; Amox-G Bronquial; Amoxi Plus; Amoxi
Respiratorio¤; Amoxidal Respiratorio Duo; Amoxidal Respiratorio; Amoxidal
Respiratorio; Amoxigrand Bronquial; Amoxigrand Compuesto; Amoxipenil
Bronquial; Amoxitenk Plus; Amoxitenk Respiratorio¤; Aseptobron
Respiratorio; Bi Moxal Duo; Bi Moxal; Bioclavid; Bioxilina Plus; Clamoxol Bio;
Clamoxol; Clavulox Duo; Clavulox; Cloximar Duo¤; Darzitil Plus Duo; Darzitil
Plus; Darzitil SB; Desinflam Biotic¤; Dibional; Fabamox Duo; Fluimucil
Biotic¤; Fullcilina Plus¤; Glifapen; Grinsil Clavulanico; Grinsil Respiratorio
Duo; Grinsil Respiratorio NF; Grinsil Respiratorio; Heliklar¤; Klonalmox;
Lertus Biotic¤; Muco Dosodos Biotic; No-Tos Biotic; Nobactam Bronquial;
Nobactam Clavulanico; Optamox Duo; Oximar Respiratorio¤; Plenobiotic
Duo; Rodinac Biotic; Trexirol NF¤; Trifamox Bronquial Duo; Trifamox
Bronquial; Trifamox IBL Duo; Trifamox IBL; Ultrabiotic Duo; Ultrabiotic;
Australia: Augmentin; Ausclav¤; Clamohexal¤; Clamoxyl; Clavulin;
Clavycillin; Curam; GA-Amclav; Klacid HP 7; Losec Helicopak¤; Losec Hp 7¤;
Nexium Hp; Probitor Hp7; Pylorid-KA¤; Somac-MA¤; Austria:
AmoclanHexal; Amoclax¤; Amoxicillin comp¤; AmoxiClavulan; Amoxicomp;
Amoxiplus; Amoxistad plus; Augmentin; Benclav¤; Benomox¤;
Betamoclav¤; Clavamox; Clavex¤; Clavolek¤; Clavoplus¤; Clavulanex¤;
CombAmox¤; Curam¤; Helicocin¤; Helipac¤; Lanoclav¤; Lekamoxiclav¤;
Oxyclav¤; Xiclav; Belgium: Amoclane; Amoxiclav; Augmentin; Clavucid;
Co-Amoxi¤; Co-Amoxilan¤; Docamoclaf¤; Brazil: Amoxifar Balsamico¤;
Amplamox AC; Anzopac¤; Augmentin¤; Betaclav¤; Bronco Cilimox¤; BroncoAmoxil¤; Bronco-Polimoxil; Clav-Air¤; Clavoxil¤; Clavulin; Claxam; Erradic;
H Bacter; Helicocid Triplice¤; Helicopac; Heliklar; Novamox; Novocilin
Balsamico¤; Omepramix; Policlavumoxil; Pylorikit; Pyloripac Retrat;
Pyloripac; Pyloritrat; Sigma Clav; Sulbamox; Trifamox; Canada: Apo-Amoxi
Clav; Clavulin; Hp-Pac; Losec 1-2-3 A; Nexium 1-2-3 A; Novo-Clavamoxin;
ratio-Aclavulanate; Chile: Ambilan Bid; Ambilan; Amolex; Augmentin Bid;
Augmentin; Clavinex Duo; Clavinex; Clavoxilina Bid; Lanzopral Heli-Pack;
Pylopac; Sulbamox; China: Aikeer; Amoksiklav; An Ke; An Qi; Anmiejun;
Ao Ge Men Ding; Ao Xian¤; Augmentin; Bang Lin; Bei Shu Lin; Bi Lin; Bi Qi
Er; Chao Qing; Curam; Diclomox; Fengkelin; Fu Wei; Haikela; Jian Ao; Jin Li
Chen; Jin Li Shu; Ju Tai; Jun Er Qing; Kai Li Da; Keng Qiang; Kun Bai; Lai
Qie Li; Litan; Luo De; Nuoke; Rui Si; Sheng Ai; Sheng Xi Kai; Shu Sa Lin;
Shu Xian Lin; Te Di; Trifamox IBL; Wei An Ke Xin; Wei Jing; Wei Qi Da; Xi
Lin; Xidilin; You Lin Jia; Czech Republic: Amoclabene; Amoksiklav;
Augmentin Duo; Augmentin; Betaklav¤; Clamox; Curam; Enhancin¤;
Forcid¤; Klamoxin¤; Medoclav; Megamox; Denmark: Bioclavid;
Spektraforte; Spektramox; Finland: Amorion Comp; Amoxi-Clavulan¤;
Amoxin Comp; Atmoform¤; Augmentin; Bioclavid; Clavamoxin Comp¤;
Clavumed; Clavurion; Clavuxal¤; Forcid¤; Helipak A; Helipak K; Losec
Helira¤; Spektramox¤; Yamoxiclav¤; France: Augmentin; Ciblor¤;
Germany: Abiclav¤; Amoclav; Amoxclav; Amoxi-Clavulan; Amoxi-saar plus;
Amoxicillin comp; Amoxiclav; Amoxidura Plus¤; Amoxillat-Clav¤; Amuclan¤;
Augmentan; Flanamox; InfectoSupramox; ZacPac; Greece: Augmentin;
Bioclavid; Forcid; Frolicin; Fugentin; Moxiclav; Tenervan; Hong Kong:
Amoksiklav; Augmentin; Clamovid; Curam; Fleming; Moxiclav; Quali-
Mentin; Hungary: Aktil; Amoclan¤; Amoclav; Augmentin-Duo; AugmentinExtra¤; Augmentin; Clavumox¤; Co-Amoxi; Curam; Enhancin; Forcid;
India: ABClox; ABCloxx; ACL; Aclav; Acticlav; Adclav; Adpax; Advent;
Aeromox; Afymox-CL; Afymox-Clav; Afymox-DT; Alclox-D; Alclox; Alepam;
Alnaclox; Amclaid; Amclo; Amclosym; Amclox DL; Amclox-LB; Amclox-LBS;
Amcloxin; Amdiclox; Ament; Amexine; Amo-C Plus; Amo-Nate; AmoclavsLB; Amoclavs; Amoclox-D; Amolac Plus DT; Amolac Plus; Amolac; Amonit
Plus; Amox-AR; Amox-LB; Amoxydase; Amoxytek D; Amoxytek; Amphy;
Ampifort; Ampoxin Plus; Amstar-Clav; Amyclox-LB; Amyclox; Amyrcl;
Anthoxin; Arclav; Ariclav; Arimox-D; Atmox-CL; Augclav; Augmentin;
Augmexx; Augnic; Augpen-LB; Augpen; Aulanic; Avclav; Axcel-L; Axcel-LS;
Bacimox; Bactoclav; Baxin-D-LB+; Bclomox; Benzoclav; Bestomax 375;
Bestomax; Betaclox; Betadac-DC; Betmox-CV; Bicidal Plus; Bicil-P; Bicil-P;
Bicil; Bilin Plus; Bilin-CS; Bilin-LB; Biomoxil-LB; Biplox-SL; Blox-DC; Bluclox;
Blumox-CA; Blumox-DXL; Blumox-LB; Blumox-XL; Bodimox-CV; BoostimLB; Boostim; Broadcure; Bromolin; C Mox; C-Clox; C-Moxy; Cadmentin;
Cadmoxin-CS; Cadmoxin-LB; Calmox; Canmox; Capiclav; Capilac XP;
Capilac; Carbomox; Carlymox; Carmox; CGV-DS; Checkmox-DX; Cidoresp;
Cinclav; Cinmox-DC; Cismox; Clafel; Clamchek; Clamox; Clamoxy A;
Clamoxy; Clamp; Clanex; Clanic; Clanoxy; Clapex; Clatimox Syr; Clatimox;
Clauvmentin; Clav-II; Clavactum; Clavage; Clavam; Clavbel; Claver; ClavidA; Clavimox; Clavipen; Clavitrax; Clavnic; Clavogard; Clavotrol; Clavox;
Clavter-LB; Clavu-M; Clavunate; Clearmox-LB; Cleblo-CL; Cleblo-CL;
Climox; Cliver-A; Clobimox; Clodax-L; Clodax; Clos-DX; Clospen; Cloxam
Plus; Cloxinova; Cluster; Clynox; Co-Symoxyl; Coax-DX; Coax; Cobacta-S;
Cobex-CL; Combo-AD; Comentin; Cosclox; Cosmoxyl; Cuclav; Curam;
Cynox; Cystamox; Damoxy-GF; Daze-MX; Delamin LB; Demoxin-CB;
Dewmox-CV; Dicam; Dicloxa-MX; Dicmoxy; Dimotic; Discloxy; Dixi;
Dualcillin; Duclav; Dupen Ped; Dynaclox; E-Amox CL; Edomox-B; EdomoxC; Elclav; Emclav; Enhancin; Erox-L; Esclox-CL; Ethiclox-LB; Etoclav;
Eudase-MX; Everclav; Exario; Famclox; Fightox; Flamclov; Flanzen-MX;
Flemiclav-LB; Flemiclav; Flemiklox-DX; Flemiklox-LBX; Forticlav; Geclave;
Geniclox; Germox; GI Kit; Glomox-C; Glymox-Plus; Glymox-Plus; Glymox;
Glyph-C; Goclav; Gramclav; GSClav; Helibact; Helikit; Helipac; Heximox;
Hibrid; Himox Plus; Himox-B; Himox-LS; Hipenox LB; Hipenox; Hosiclav; HP
Kit; Imox-Clo LB¤; Imox-Clo; Impromox; Indcel; Indclav; Inloxy-LB Kid;
Inloxy-SLB; Inloxy; Inmox Clav; Intamox-D; IV Augclav; Jinclox; Kalmox;
Kemox Plus; Kindclav; Kistan; Klamoric; Klavoclav; Klomox; Krusade;
Labzone; Laciclav; Laclomox; Lacom-CV 625; Lacom-CV; Lacom; Lactoclav;
Lactomox; Lakmox-CL; Lamna-C; Lamoxy-BX; Lansi Kit; Laxclav-LB;
Laxclav; Laxlb; LC-Mox; Lebzone; Leclav; Leemoxin-CS; Leemoxin-LB;
Lemna-C Kid; Lexmox-DC; Linaox-Clav; Lizamox-D; LMX Forte; LMX; LokitKit; Lomox-D; Lupimox Forte; Lyser-A Plus; M-Clav; M-Klav; M-Mox Plus;
Magclox-LB; Maxclav; Maximizin; Mediclav; Mega-CV; Megaclav;
Megamentin; Megamox; Megox; Mikclav; Mikilac Kidtab; Mikilac Plus;
Mikilac; Minoclav; Mintclav; Moclox; Mokcan-C LB; Mokcan-C; Monamox-BR;
Monamox-CL; Monomox-DX; Mordica; Mordica; Mox P; Moxbro; Moxclav;
Moxer; Moxflora; Moxiclox; Moxifact; Moxifast-CV; Moxigem; Moxikare;
Moxikind Plus; Moxikind-CV; Moxikind; Moxind BR; Moxinova CV; MoxinovaDT; Moxinta-LB; Moxiphar-CV; Moxipi; Moxipil-CL; Moxipil-CV; Moxipil-L;
Moxipil-LB; Moxiplus-CV; Moxitrac-CV; Moxitrac-DX; Moxiz CV; Moxklok;
Moxlox-L; Moxlox; Moxnic; Moxsav; Moxspen-CL; Moxtid-CS; Moxtid-D;
Moxtive-Clav; Moxxil-Duo; Moxy Plus-CV; Moxycarb; Moxycare; Moxyclav;
Moxynic; Moxyplus-DC; Moxyplus-SL; Moxyvent; Mpx-CV; Mucobron;
Mucoclav; Mucomox; Muconal; Myclav; Mycocin; Mytimox; Nataclox;
Nayaclav; NBMox-DC; Neclav; Netclav; Neucomox; Nikomox-CV; Nismentin;
Nizoclav; Nodimox Plus-LB; Nodimox Plus; Nodimox-LB; Noir; Novaclav;
Novaclox LB; Novaclox; Novamox AX; Novamox LB; Novamox-CV; Nuclav;
Nuclox; Nugen-XL; Numox-LB; Numox; O-Moxy-CL; O-Moxy-DC; Oclam;
Odimox-DL; Ogmen; Oleclox; Omepraz-HP Kit; Omlar-CV; Omoxitin;
Onamox-CL; One Clav; Orgamox-CL BD; Orgamox-CL; Osclav; Osoclox;
Otymox; Oxybro; Oxylac; Pamclav; Pantocid-HP; Pantop-HP Kit; Rapiclav¤;
Respimox; Suprimox; Symbiotik; Symoxyl-LB; Indonesia: Amocomb;
Ancla; Augmentin; Auspilic; Bellamox; Betaclav; Biditin¤; Capsinat; Clabat;
Claneksi; Clavamox; Claxy; Comsikla; Danoclav; Daxet; Dexyclav; Ikamoxyl
Plus; Improvox; Lansiclav; Nufaclav; Nuvoclav; Palentin; Prafamoc¤;
Protamox; Surpas; Syneclav; Viaclav; Vibranat; Vulamox; Zumafen¤;
Ireland: Amoclav; Augmentin; Bellmentin¤; Clavamel; Germentin;
Pinaclav; Israel: Amoxiclav; Augmentin; Clavamox; Clavenir; Claventin;
Moclav; Italy: Abba; Acadimox; Aklav; Anival; Augmentin; Aveggio;
Clavulin; Dicil¤; Duplamox Mucolitico¤; Duplamox¤; Euticlavir; Flanamox¤;
Homer; Klavux; Kruxade; Levantes; Mondex; Moxacin¤; Moxiprim¤;
Moxivul; Neoduplamox; Puriclav; Servamox¤; Stacillin¤; Velamox D¤;
Xinamod; Malaysia: Augmentin; Cavumox; Clamentin; Clamovid; Clavam;
Clavomid; Curam; Enhancin; Klacid HP 7; Moxiclav; Myclav; Vestaclav¤;
Mexico: Acarbixin; Acimox AC; Acimox-Ex; Acroxil-C; Alvi-Tec; Ambrexin¤;
Amobay CL; Amoxibron; Amoxiclav; Amoxiclide; Ampliron Duo; Apoclavox;
Augmentin; Avuxilan; Biovicam Ex; Bolbamox¤; Bremoxiral; Bromel¤;
Bromixen; Bromoxil; Broxolim-AM¤; Brumax; Cibronal; Clambusil;
Clamoxin; Clavant; Clavucyd; Clavulin; Clavuser; Crizmat; Enhancin;
Esteclin Bac¤; Eumetinex¤; Ferlex; Gimabrol¤; Gramaxin; Hidramox-M;
Loexom FC; Loexom FS; Lumoxbron S; Maxint¤; Megamox; Moxlin CLV;
Mucovibrol Amoxi; Mucoxina; Penamox M; Pentibroxil; Pylopac; Rapiclav;
Ravotaf; Riclasip; Sekretovit Amoxi; Septacin Amoxi; Sermoxol; Servamox
CLV; Sinufin; Solcibrol; Toxol; Trifamox IBL; Valclan¤; Vanmoxol¤;
Netherlands: Amoclan¤; Amuclan¤; Augmentin; Bioclavid; Forcid;
PantoPAC; Zymolav; Norway: Bremide¤; New Zealand: AlphaAmoxyclav¤; Augmentin; Curam; Helicosec¤; Klacid HP 7¤; Losec Hp7;
Synermox; Philippines: Addex; Agcomen; Alvonal; Amoclav; Anbicyn;
Atadar; Augmentin; Augmex¤; Augurcin; Bactiv; Bactoclav; Bioclav;
Bioclavid; Cax; Clamovid; Clamoxil; Claneksi; Clavasul; Claventin;
Clavimox; Clavmex; Clavomax; Clavorex; Clavox; Clavoxel; Clavoxin;
Clovimax; CO-AX; Comxicla; Duotak; Enhamox; Enhancin; Exten;
Globantin; Gloclav; Julmentin; Klavic; Luvmox; Natravox; Nexilav; OAC
Hp7¤; Penhance; Proxiclav; Rafonex; Sanmox¤; Solclav; Sovlan; Sullivan;
Suplentin¤; Ultramox; Valmocel¤; Vamox; Xilanic; Poland: Amoclan;
Amoksiklav; Augmentin; Curam¤; Forcid; Ramoclav¤; Taromentin;
Portugal: Amoclavam; Amplamox Plus¤; Augmentin; Betamox; Clavamox;
Clavepen; Forcid; Noprilam; Penilan; Russia: Amoclan (Амоклан)¤;
Amoksiklav (Амоксиклав); Arlet (Арлет); Augmentin (Аугментин);
Clamosar (Кламосар); Ecoclav (Экоклав); Flemoclav (Флемоклав); Liclav
(Ликлав); Medoclav (Медоклав); Panklav (Панклав); Ranclav (Ранклав);
Rapiclav (Рапиклав); Trifamox IBL (Трифамокс ИБЛ); South Africa: AdcoAmoclav; Amoclan; Apex-Clavutin; AugMaxcil; Augmentin; Auro-Amoxiclav;
Bindoclav; Bio-Amoksiclav; Bio-Amoksiklav; Clamentin; Clavumox; CoAmoxyclav; Curam; Flumox¤; Forcid; Hiconcil-NS¤; Losec 20 Triple¤;
Macropen; Megapen; Moxyclav¤; Ranclav; Rolab-Amoclav¤; Suprapen;
Singapore: Amocla; Augmentin; Augmex¤; Clamonex; Clamovid; Curam;
Enhancin; Fugentin¤; Moxiclav; Spain: Agerpen Mucolitico¤; Amo Resan¤;
Amoclave; Amoxi Gobens Mucolitico¤; Amoxidel Bronquial¤; Amoxtiol¤;
Amoxyplus¤; Ardine Bronquial¤; Ardineclav¤; Argemox Mucolitico¤;
Augmentine; Bigpen¤; Bimoxi Mucolitico¤; Bisolvon Amoxycilina¤;
Brisantin¤; Brolimine Antibiotico¤; Bronco Quintoxil¤; Bronco Tonic¤;
Bronconovag¤; Bronquium Amoxicilina¤; Broxamox¤; Burmicin¤; Cilinvita
Bronquial¤; Clamoxyl Mucolitico; Clavepen¤; Clavius¤; Clavucid¤;
Clavumox¤; Cliptobiotico¤; Combitorax¤; Damoxicil Mucolitico¤; Duonasa;
Edoxil Mucolitico¤; Eupeclanic¤; Eupen Bronquial¤; Halitol Mucolitico¤;
Hortemox¤; Hosboral Bronquial¤; Inexbron Mucolitico¤; Inmupen¤;
Kelsopen¤; Lisoxil¤; Metifarma Mucolit¤; Moxipin Mucolitico¤; Naxina¤;
Neumobronquial¤; Odontobiotic; Pangamox¤; Pectomox¤; Precopen
Mucolitico¤; Prosbis¤; Pulmo Borbalan¤; Rea Amoxicilina¤; Rea Tos
Amoxicilina¤; Reloxyl Mucolitico¤; Remisan Mucolitico¤; Salvapen
Mucolitico¤; Sinus¤; Sobrepin Amoxi¤; Superpeni Mucolitico¤; Tusolone¤;
Ultramoxil¤; Sweden: Bioclavid; Nexium Hp; Spektramox; Switzerland:
Amicosol¤; Augmentin; Aziclav; Clavamox¤; clavu-basan¤; Co-Amoxi; CoAmoxicillin; Co-Amoxicilline; CoAmox; Thailand: AMK; Amocla¤;
Amoksiklav; Anbicyn; Augclav; Augmentin; Augpen¤; Biclav; Cavumox;
Clavmoxy; Clavomid; Curam; Ind Clav; Klamoks¤; Manclamine; Moxiclav;
Moxicle; Pencla¤; Ranclav; Verclav; Turkey: Amoklavin; Augmentin;
Bioment; Croxilex; Helipak; Klamoks; Klavunat; Klavupen; Trio; United
Arab Emirates: Julmentin; United Kingdom: Amiclav¤; Augmentin-Duo;
Augmentin; Heliclear¤; Ukraine: Amoksiklav (Амоксиклав); Amoxicomb
(Амоксикомб); Amoxil-K (Амоксилу-К); Augmentin (Аугментин); Bactoklav
(Бактоклав); Betaklav (Бетаклав)¤; Clavam (Клавам); Esoxium Combi
(Эзоксиyм Комби); Flemoclav (Флемоклав); Klamox (Кламокс)¤; Panclav
(Панклав); Pylobact Neo (Пилобакт Нео); United States: Amoclan;
Augmentin; Omeclamox-Pak; Prevpac; Venezuela: Augmentin Bid¤;
Augmentin; Clavumox; Curam; Fulgram;
Pharmacopoeial Preparations (Latest modification: 25-Jul-2013)
BP 2013: Amoxicillin Capsules; Amoxicillin Injection; Amoxicillin Oral
Suspension; Co-amoxiclav Injection; Co-amoxiclav Oral Suspension; Coamoxiclav Tablets; Dispersible Co-amoxiclav Tablets; USP 36: Amoxicillin
and Clavulanate Potassium for Oral Suspension; Amoxicillin and Clavulanate
Potassium Tablets; Amoxicillin and Clavulanic Acid Extended-Release
Tablets; Amoxicillin Capsules; Amoxicillin for Oral Suspension; Amoxicillin
Tablets for Oral Suspension; Amoxicillin Tablets;
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Martindale: The Complete Drug Reference © 2013 The Pharmaceutical Press.
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Amoxicillin

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