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Program
VI International Symposium Helicobacter pylori:
natural history and implications for human health
Wednesday, December 3, 2014
07:30-12:00 Registration
08:00-08:30 Opening
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Words of Vanessa Ramírez, Coordinator.
Words of Patricia Cuenca, Director INISA.
Cultural act of Grupo de Música de Cámara Arcadas
Quinteto de cuerdas:
Mariamalia Altamirano (I violín)
Mónica Orozco (II violín)
Eloísa Orozco (viola)
María José Vargas (violoncello)
Verónica Vargas (contrabajo)
Words of the representative of the Rector of the University of Costa Rica
08:30-10:00 Inaugural Lectures (Chair: Guillermo Pérez-Pérez, Francis Mégraud)
08:30-09:15
09:15-10:00
Pelayo Correa: Helicobacter pylori and gastric pathologies overview.
USA.
Richard Peek: New insights into H. pylori-induced gastric cancer. USA.
10:00-10:45 Coffee break
10:45-12:45 Session 1: Epidemiology and Molecular Characterization (Chair: María
Constanza Camargo, Vanessa Ramírez)
10:45-11:15 María Constanza Camargo. Gastric Cancer: Opportunities for Etiologic
Research and Prevention. USA.
11:15-11:45 Catterina Ferrecio. Preliminary results of a population-based study of
Helicobacter pylori and co-factors in two distinct areas of stomach
cancer risk in Chile. Chile.
11:45-12:15 Douglas Morgan. Gastric cancer molecular epidemiology: Insights from
the Honduras population-based initiatives and beyond. USA.
12:15-12:45 Charles Rabkin. Epidemiologic and molecular features of EBV-positive
gastric cancer. USA.
12:45-13:45 Lunch
VI International Symposium Helicobacter pylori: natural history and implications for human health
2014
13:45-15:45 Session 1(continued): Epidemiology and Molecular Characterization
(Chair: María Constanza Camargo, Vanessa Ramírez)
13:45-14:15 Karen Goodman. Community-driven research aimed at reducing health
risks from H. pylori infection. Canada.
14:15-14:45 Michael Bruce. Helicobacter pylori infection in the Alaska Native
population. USA.
14:45-15:15 Luis Carvajal. Exome sequencing of gastric tumors from Latin American
patients. USA.
15:15-15:45 Ichizo Kobayashi. Helicobacter pylori evolution. Japan.
15:45-16:15 Coffee break: poster rounds
P01: Epidemiology and Molecular Characterization
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Trini Fragoso. Úlcera duodenal por infección Helicobacter pylori en un servicio
ambulatorio durante 10 años. Cuba.
Ezequiel Fuentes. Serological Evidence that Epstein Barr Virus Cooperates with
Helicobacter pylori to Increase Risk of Severe Gastric Inflammation and of preand Cancerous Lesions. México.
Gabriel Arismendi. Estimación de riesgo de cáncer gástrico en pacientes con
gastritis crónica asociada a la infección por Helicobacter pylori en un escenario
clínico. Venezuela
Jorge Touma. Análisis bioinformático del gen cagA en genomas de H. pylori
disponibles en GENBANK. Chile
José Eduardo Mucito Varela. Genome Sequencing of Helicobacter pylori strains
isolated in Mexico from Gastric Cancer and Chronic Gastritis Lesions. Mexico.
Modesto Cruz. Helicobacter pylori en la República Dominicana: Caracterización
molecular y factores de virulencia. República Dominicana
P04: Clinical Manifestations and Treatment
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Trini Fragoso. Terapia secuencial en escolares y adolescentes infectados por
Helicobacter pylori en un servicio ambulatorio. Cuba.
Francisco Rivas. Morphologic, genetic, and biochemical characterization of
Helicobacter magdeburgensis, a novel species isolated from the intestine of
laboratory mice. Panamá
Álvaro R. Bedoya Urresta. Prevalencia de lesiones precursoras de malignidad
gástricas y efecto del tratamiento inicial de erradicación de la infección por
Helicobacter pylori, un primer paso para el desarrollo de estrategias de
prevención primaria de cáncer gástrico en población de riesgo alto del
Departamento de Nariño, Colombia. Colombia.
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VI International Symposium Helicobacter pylori: natural history and implications for human health
2014
16:15-18:45 Session 2: Pathogenesis and Host Response. (Chair: James Fox, Warner
Alpízar)
16:15-16:45 James Fox. Male 129 Rag Mice Co-Infected with Helicobacter pylori and
Helicobacter hepaticus Develop More Severe Colitis than Monoinfected
H. hepaticus Mice. USA.
16:45-17:15 Keith T. Wilson. Chemoprevention of gastric carcinogenesis by targeting
ornithine decarboxylase in high risk populations. USA.
17:15-17:45 Eliette Touati. Consequences of H. pylori infection on mitochondria and
their genome., France.
17:45-18:15 Michael Naumann. Host response and molecular pathology in
Helicobacter infected patients. Germany.
18:15-18:45 Céu Figueiredo. The stomach microbiota in gastric carcinogenesis.
Portugal.
Thursday, December 4, 2014
08:00-10:30 Session 3: Diagnosis and Disease Markers (Chair: Javier Torres, Clas Une)
08:00-08:30 Luiz Gonzaga Vaz Coelho. Contribution of 13C-urea breath test to the
knowledge of H. pylori infection. Brazil.
08:30-09:00 Javier Torres. Biomarkers for the early detection of patients at risk for
gastric cancer in Latin American populations. México.
09:00-09:30 Guillermo Pérez-Pérez. Characterization of the stomach microbiota by
high-through-put sequencing and the role of Helicobacter pylori. USA.
09:30-10:00 Gunilla Høyer-Hansen. Prognostic, diagnostic and predictive value of
intact and cleaved forms of the urokinase plasminogen activator
receptor in cancer. Denmark.
10:00-10:30 Michael Ploug. Development of PET-tracer for the specific non-invasive
imaging of the urokinase receptor in cancer. Denmark.
10:30-11:00 Coffee break: posters rounds
P02: Pathogenesis and Host Response
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Ezequiel Fuentes. Helicobacter pylori CagA suppresses apoptosis through
activation of AKT in a model of non-transformed epithelial cells. México
Stephanie Morales. Gene expression profiling in chronic gastritis associated
with Helicobacter pylori infection. México
Wendy Malespín. TNF-A–857*T polymorphism is associated with gastric
carcinoma in a Costa Rican population. Costa Rica.
Lindsay Borjas / Dayana Herrera. Polimorfismos en los genes de TLR-2 y TLR-4
no asociados con patologías gástricas en una población de Costa Rica. Costa
Rica.
Modesto Cruz. Helicobacter pylori gastric mucosa infection in the Dominican
Republic population: genotype and interleukin-8 expression. República
Dominicana.
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VI International Symposium Helicobacter pylori: natural history and implications for human health
2014
P03: Diagnosis and Disease Markers
 Trini Fragoso. Comportamiento del diagnóstico de la infección por Helicobacter
pylori en niños y adolescentes en un servicio ambulatorio. Cuba.
 Alejandro Venegas. Desarrollo de un sistema de diagnóstico por PCR múltiple
para Helicobacter pylori basado en segmentos conservados de 6 genes y
comprobado por análisis genómico IN SILICO. Chile
 Mónica Barbosa. Detection of molecular Helicobacter pylori and comparison
with test rapid urease. Brasil.
 Ericka Méndez. Validación de una prueba serológica para detectar la infección
por Helicobacter pylori en Costa Rica. Costa Rica.
 Giulano Bernal. Detection of Helicobacter pylori by nested Real Time-PCR, in
fecal samples of Chilean patients. Chile.
 Martha Pérez Rodríguez. Genes KIR (killer cell immunoglobulin-like receptor)
en lesiones gástricas. México.
11:00-12:15 Parallel workshops 1 & 2
W01: Epidemiology and Molecular Characterization (Chair: María Constanza Camargo,
Vanessa Ramírez) – Classroom
11:00-11:15
11:15-11:30
11:30-11:45
11:45-12:00
12:00-12:15
Vanessa Ramírez. Prevalencia de la infección por el Virus de Epstein
Barr en una población costarricense con cáncer gástrico. Costa Rica
Francisca Jaime. Prevalence of Helicobacter pylori infection and its
relationship with abdominal pain and functional gastrointestinal
disorders (Rome III) in students with low socioeconomic status. Chile.
Paula Troncoso. Helicobacter pylori status in newborns and infants from
infected mothers. Chile.
Virginia Montero Campos. Prevalencia de Helicobacter pylori en biopsias
gástricas de pacientes dispépticos de zonas de alta y baja incidencia de
cáncer gástrico en Costa Rica. Costa Rica.
Elisa Hernández. Identificación y evaluación de lesiones gástricas premalignas asociadas a infección por Helicobacter pylori y propuesta de
una estrategia de prevención. Guatemala.
W02: Pathogenesis and Host Response (Chair: James Fox, Warner Alpízar)- Auditorium
11:00-11:15 Andrew Quest. The Helicobacter pylori virulence factors GGT and CagA
regulate gastric cell survival in opposing ways. Chile.
11:15-11:30 Paul Harris. Different strains of H. pylori induce tolerogenic dendritic
cells in children. Chile.
11:30-11:45 Mario Vásquez. Patrones de metaplasia intestinal en pacientes con
cáncer gástrico operado en el Hospital San Juan de Dios del 2007 al
2014. Costa Rica.
11:45-12:00 Warner Alpízar. Expression of the urokinase receptor (uPAR) in gastric
adenocarcinomas and non-neoplastic gastric mucosa. Costa Rica.
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VI International Symposium Helicobacter pylori: natural history and implications for human health
2014
12:00-12:15 Andrea Villagrán. TGF-B1 And The Inverse Association Between
Helicobacter pylori Infection And Inflammatory Bowel Disease In
Children. Chile.
12:15-13:15 Lunch
13:15-15:15 Session 4: Clinical Manifestations and Treatment (Chair: Francis Mégraud,
Rolando Páez)
13:15-13:45 Francis Mégraud. Is there one optimal treatment for a Helicobacter pylori
infection? France.
13:45-14:15 Tamara Matysiak. Diagnosis and management of gastric precancerous
lesions. France.
14:15-14:45 Leif Andersen. Rational diagnosis of Helicobacters. Department of
Infection Control, Denmark.
14:45-15:15 Rolando Herrero. Erradicación de H. pylori para prevención de cáncer
gástrico: Reporte del Grupo de Trabajo de la IARC. France.
15:15-15:45 Coffee break
15:45-18:00 Keynote lectures (Chair: Richard Peek, Guillermo Pérez-Pérez)
15:45-16:30 Martin Blaser. Complex biology of Helicobacter pylori and humans: the
bad and the good. USA.
16:30-17:15 John Atherton. H. pylori strain determinants of gastric cancer risk…and
are any strains entirely non-pathogenic? United Kingdom.
17:15-18:00 Jean Crabtree: Extra-gastric manifestations of childhood Helicobacter
pylori infection in developing countries. United Kingdom.
18:15 Cocktail and Cultural act of Ensamble Folklórico Gamonal
Friday, December 5, 2014
08:00-10:30 H. pylori and pathologies in Latin America (Chair: Pelayo Correa, Catterina
Ferrecio, Beatriz Gutiérrez, Francis Mégraud)
08:00-08:15
08:15-08:30
08:30-08:45
08:45-09:00
09:00-09:15
09:15-09:30
09:30-09:45
09:45-10:00
10:00-10:30
Costa Rica: Vanessa Ramírez Mayorga
Colombia: María Constanza Camargo
México: Javier Torres
Chile: Catterina Ferrecio
Cuba: Beatriz Gutiérrez
El Salvador: Douglas Morgan
Honduras: Douglas Morgan
Guatemala: Carmen Villagrán de Tercero
Discussion of conferences
10:30-11:00 Coffee break
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VI International Symposium Helicobacter pylori: natural history and implications for human health
2014
11:00-12:15 Parallel workshops 1 & 3
W01 (continued): Epidemiology and Molecular Characterization (Chair: María
Constanza Camargo, Vanessa Ramírez) - Auditorium
11:00-11:15 Maria Bravo. Genotipificación de los factores de virulencia vacA y cagA
de Helicobacter pylori en individuos de dos regiones de Colombia con
riesgo opuesto de cáncer gástrico. Colombia.
11:15-11:30 Carolina Serrano. Native Residents of Easter Island (Rapa Nui) in
Polynesia are colonized by european origin H. pylori (HpEurope). Chile.
11:30-11:45 Paul Harris. Fecal microbiota and its relationship with Helicobacter
pylori infection in mother-child pairs. Chile.
11:45-12:00 Kaisa Thorell. Identification of a Latin American specific babA variant
through whole genome sequencing of Helicobacter pylori patient isolates
from Nicaragua. Sweden.
12:00-12:15 Virginia Montero Campos. Cultivo e identificación molecular de
Helicobacter pylori en el agua potable de las zonas de alta y baja
incidencia de cáncer gástrico en Costa Rica. Costa Rica.
W03: Diagnosis and Disease Markers (Chair: Javier Torres, Clas Une) - Classroom
11:00-11:15 Marcis Leja. Volatile marker testing for gastric cancer and H. pylorirelated gastric precancerous lesion detection. Latvia.
11:15-11:30 Carmen Mandonado Bernal. Identificación de biomarcadores de riesgo en
cáncer gástrico. México.
11:30-11:45 Alejandro Corvalan. Liquid Biopsy for Non-invasive Detection of Gastric
Cancer. Chile
11:45-12:00 Clas Une. Helicobacter pylori infection and Serum pepsinogen
concentrations in an elderly population representative of Costa Rica.
Costa Rica.
12:15-13:15 Lunch
13:15-15:45 CagPAI genes mini-symposium (Chair: Martin Blaser, Steffen Backert)
13:15-13:45 Steffen Backert: Signal transduction of the Helicobacter pylori type IV
secretion system and CagA effector protein. Germany
13:45-14:15 Manuel Amieva. Helicobacter pylori colonization of the stem cell
compartment. USA.
14:15-14:45 Jay V. Solnick. Functional plasticity in the type IV secretion system of
Helicobacter pylori. Center for Comparative Medicine, University of
California, USA.
14:45-15:15 Masanori Hatekayama. Role of Helicobacter pylori CagA oncoprotein in
gastric carcinogenesis. Division of Microbiology, Graduate School of
Medicine, University of Tokyo.
15:15-16:00 Presentation of the next meeting and closing remarks
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