Supplementary Information Drug-tubulin interactions interrogated by

Electronic Supplementary Material (ESI) for RSC Advances.
This journal is © The Royal Society of Chemistry 2015
Supplementary Information
Drug-tubulin interactions interrogated by transient absorption
spectroscopy
F. Boscáa, G. Sastrea, J. M. Andreub, D. Jorneta, R. Tormosa*and M. A. Mirandaa
a Departamento
de Química/Instituto Universitario Mixto de Tecnología Química UPV-CSIC, Avenida de los Naranjos
s/n, E-46022 Valencia, Spain.
b Centro de Investigaciones Biológicas, CSIC, Ramiro de Maeztu 9 E-28040 Madrid, Spain.
Fig.1S Trajectories across xy of the centre-of-mass coordinates of COL in TU obtained from the molecular dynamics run (1ns, in
red and superimposed up to 10 ns , in gray).