Sincronización de celos y ovulaciones 189

Sincronización de celos y ovulaciones 189

Sincronización de celos y ovulaciones
189
SINCRONIZACIÓN DE CELOS Y OVULACIONES EN EL GANADO BOVINO
Gabriel A Bó &
Santiago Callejas
Introducción
Desde el descubrimiento de las hormonas de la reproducción, el hombre ha pretendido
controlar la actividad reproductiva. La utilización de la ultrasonografía para estudiar el efecto de
distintos tratamientos hormonales sobre la dinámica folicular en el bovino llevó al desarrollo de
protocolos que permiten manipular eficientemente el ciclo estral y la ovulación. Existen hoy
numerosos protocolos de sincronización de celos y ovulaciones y cada uno de ellos tiene sus ventajas
y desventajas. Es por esto que se debe tener un conocimiento profundo de la fisiología reproductiva
del bovino para determinar cuál es el método más adecuado para los distintos ambientes y animales
con los que debe trabajar. El presente capitulo tiene por objeto realizar una descripción de los
tratamientos disponibles para sincronizar los celos y la ovulación en el ganado bovino.
190
Bó & Callejas
Bibliografía
Alberio R, Schiersmann G, Conosciuto G, Sanchez O (1978) Control del ciclo estral en vaquillonas,
vacas secas y vacas en lactancia de razas de carne por medio del Cloprostenol Analecta
Veterinaria 10-11, 225-245
Aller JF, Alberio R, Ridruejo E, H Butler (1997) Sincronización de celos en vaquillonas con
Cloprostenol o su combinación con Buserelina Rev Arg Prod Anim 17 (supl. 1), 249
Bao B, Garverick HA, Smith GW, Smith MF, Salfen BE, RS Youngquist (1997) Changes in messenger
ribonucleic acid encoding luteinizing hormone receptor, cytochrome P450-side chain cleavage,
and aromatase are associated with recruitment and selection of bovine ovarian follicles Biol
Reprod 56, 1158-1168
Baruselli PS, Madureira EH, MO Marques (2001) Programas de IA a tiempo fijo en Bos indicus. IV
Simposio Internacional de Reproducción Animal, Huerta Grande, Córdoba, Argentina, 95-116
Baruselli PS, Reis EL, Marques MO, Nasser LF, GA Bó (2004) The use of treatments to improve
reproductive performance of anestrus beef cattle in tropical climates Anim Reprod Sci 82-83, 479486
Baruselli PS, Bó GA, Reis EL, Marques MO, Sá MF Filho (2005) Introdução da IATF no manejo
reproductivo de rebanhos bovinos de corte no Brasil VI Simposio Internacional de Reproducción
Animal, Córdoba, Argentina, 151-176
Baruselli PS, Sales JN, Crepaldi GA, Marques MO, Pentenado L, GA Bo (2007) Aplicación integrada
de programas de control de la ovulación y manejo reproductivo en bovinos de carne criados en
condiciones extensivas VII Simposio Internacional de Reproducción Animal, Córdoba Argentina,
55-79
Ben G (1996) Estrategias para controlar el ciclo estral en vaquillonas de cria Tesina Facultad de
Ciencias Veterinarias (UNCPBA), Tandil, Argentina 19 páginas.
Bó GA, Pierson RA, RJ Mapletoft (1991) The effect of estradiol valerate on follicular dynamics and
superovulatory response in cows with Syncro-Mate-B implants Theriogenology 36,169-183.
Bó GA, Adams GP, Nasser LF, Pierson RA, RJ Mapletoft (1993) Effect of estradiol valerate on ovarian
follicles, emergence of follicular waves and circulating gonadotropins in heifers Theriogenology 40,
225-239
Bó GA, Adams GP, Pierson RA, Caccia M, Tríbulo H, RJ Mapletoft (1994a) Follicular wave dynamics
after estradiol-17β treatment of heifers with or without a progestogen implant Theriogenology 41,
1555-1569
Bó GA, Caccia M, Tríbulo H, Adams GP, Pierson RA, RJ Mapletoft (1994b) Synchronous ovulation in
heifers treated with E-17ß and CIDR-B vaginal devices Proc Can Society Anim Sci Regina, SK,
284
Bó GA, Adams GP, Caccia M, Martínez M, Pierson RA, Mapletoft RJ (1995) Ovarian follicular wave
emergence after estradiol and progestogen treatment in cattle Anim Reprod Sci 39,193-204.
Bó GA, Caccia M, Martínez M, RJ Mapletoft (1996) Follicular wave emergence after treatment with
estradiol benzoate and CIDR-B vaginal devices in beef cattle 13 th International Congress on
Animal Reproduction, Sydney, Austrália, 2, 7-22.
Bó GA, Medina M, Tegli JC, Costamagna A, GM Brogliatti (2000) Fixed-time artificial insemination in
CIDR-B treated cows induced to ovulate with estradiol benzoate or GnRH. 14th International
Congress on Animal Reproduction (ICAR), Stockholm, Sweden, 2, 45
Bó GA, Cutaia L, Brogliatti GM, Medina M, Tríbulo R, H Tríbulo (2001) Programas de inseminacion
artificial a tiempo fijo en ganado bovino utilizando progestágenos y estradiol. VI Simposio
Internacional de Reproducción Animal, Huerta Grande, Córdoba, 117-136
Bó GA, PS Baruselli (2002) Programas de Inseminación Artificial a Tiempo Fijo en el Ganado Bovino
en Regiones Subtropicales y Tropicales. Capítulo XXXI. En: Avances en la Gandería doble
propósito, C. Gonzalez-Stagnaro, Eleazar Soto Belloso y Lílido Ramírez Iglesia (Editores);
Fundación Girarz, Maracaibo, Venezuela, 499-514
Bó GA, Baruselli PS, Moreno D, Cutaia L, Caccia M, Tríbulo R, Tríbulo H, RJ Mapletoft (2002a) The
control of follicular wave development for self-appointed embryo transfer programs in cattle.
Theriogenology 57, 53-72
Bó GA, Cutaia L, R Tribulo (2002b) Tratamientos hormonales para inseminación artificial a tiempo fijo
en bovinos para carne: algunas experiencias realizadas en Argentina, Primera Parte, Taurus 14,
10-21
Sincronización de celos y ovulaciones
191
Bó GA, Cutaia L, R Tribulo (2002c) Tratamientos hormonales para inseminación artificial a tiempo fijo
en bovinos para carne: algunas experiencias realizadas en Argentina, Segunda Parte, Taurus 15,
17-32
Bó GA, Baruselli PS, MF Martinez (2003) Pattern and manipulation of follicular development in Bos
indicus cattle Anim Reprod Sci 78, 307-326
Bo GA, Cutaia L, Chesta P, Balla E, Pincinato D, Peres L, Maraña D, Avilés M, Menchaca A,
Veneranda G, PS Baruselli (2005) Implementacion de programas de inseminación artificial en
rodeos de cría de argentina VI Simposio Internacional de Reproducción Animal, Córdoba,
Argentina, 97-128
Bó GA, Pincinato D, Peres LC, Cutaia L, Nasser LF, PS Baruselli (2006) Protocolos de Transferencia
de Embriones a tiempo fijo para receptoras de embriones bovinos Acta Scientiae Veterinaire 34
(Supl 1), 17-23
Bó GA, Cutaia LE, Souza AH, PS Baruselli (2007). Systematic Reproductive Management in Dairy
Herds. New Zealand Veterinary Association (NZVA) Conference 2007, Dairy Cattle Conference,
Christchurch, New Zealand (disponible on line en SciQuest), 155-168
Bodensteiner KJ, Kot K, Wiltbank MC, OJ Ginther (1996) Synchronization of emergence of follicular
waves in cattle Theriogenology 45, 1115-1128
Burke J, De La Sota L, Risco C, Staples C, Schmitt J, WW Thatcher (1996) Evaluation of timed
insemination using a Gonadotropin-Releasing Hormone agonist in lactating Dairy cows J Dairy Sci
79, 1385-1393
Burke CR, Mussard ML, Grum DE, ML Day (2001) Effects of maturity of the potential ovulatory follicle
on induction of estrus and ovulation in cattle with estradiol benzoate Anim Reprod Sci 66,151-160
Butler H, Aller J, Ross P, Mac Dermott E, Cano A, A Saenz (2001) Distribución de los celos y
fertilidad en vaquillonas para carne con doble aplicación a diferentes dosis de un agente
luteolítico Taurus 10, 16-20
Calá M, Callejas S, Catalano R, Ersinger C, Cabodevila J, M Teruel (1999) Control del ciclo estral en
vaquillonas lecheras mediante la administración de Buserelina y Tiaprost. III Simposio
Internacional de Reproducción Animal, Carlos Paz, Córdoba, Argentina, 187
Callejas S, Ersinger C, Cabodevila J, Catalano R, M Teruel (1999) Uso de la Hormona Liberadora de
Gonadotrofinas y de la Prostaglandina F2α para realizar una Inseminación Artificial Sistemática
Taurus 2, 4-8
Callejas S, Scena C, Ersinger C, Cabodevila J, Catalano R (2000) Control del ciclo estral en vacas
lecheras Uso del norgestomet, gonadorelina y luprostiol XVI Congreso Latinoamericano de
Producción Animal (en CD)
Caravielllo DZ, Weigel KA, Fricke PM, Wiltbank MC, Florent MJ, NB Cook (2006) Survey of
management practices related to the reproductive performance of dairy cattle on large commercial
farms in the United States J Dairy Sci 89, 4723-4735
Cavalieri J, Rubio I, Kinder JE, Entwistle KW, Fitzpatrick LA (1997) Synchronization of estrus and
ovulation and associated endocrine changes in Bos indicus cows Theriogenology 47, 801-814.
Cavalieri J, Coleman C, Rodrigues H, Macmillan KL, LA Fitzpatrick (2002) The effect of timing of
administration of oestradiol benzoate on characteristics of oestrus, timing of ovulation and fertility
in Bos indicus heifers synchronised with a progesterone releasing intravaginal insert Aust Vet J
80, 217-223
Cesaroni G, Butler H, Mc Dermott E, A Cano (2000) Preñez de vaquillonas inseminadas a tiempo fijo
después de un tratamiento con CIDR asociado con GnRH o con benzoato de estradiol aplicado 0
o 24 hs postratamiento Taurus 6, 20-25
Colazo MG, Bó GA, Illuminanti H, Meglia G, Schmidt EE, J Bartolomé (1999) Fixed-time artificial
insemination in beef cattle using CIDR-B devices, progesterone and estradiol benzoate.
Theriogenology 51, 404
Colazo MG, Kastelic JP, RJ Mapletoft (2003) Effects of estradiol cypionate (ECP) on ovarian follicular
dynamics, synchrony of ovulation, and fertility in CIDR-based, fixed-time AI programs in beef
heifers Theriogenology 60, 855-865
Colazo MG, Kastelic JP, Martinez MF, Whittaker PR, R Wilde (2004) Fertility follawing fixed-time AI in
CIDR treated beef heifers given GnRH or estradiol Cypionate and fed diets supplemented with flax
seed or sunflower seed Theriogenology 61, 1115-1124
Colazo MG, Martinez MF, Small JA, Kastelic JP, Burnley CA, Ward DR, RJ Mapletoft (2005) Effect of
estradiol valerate on ovarian follicle dynamics and superovulatory response in progestin-treated
cattle Theriogenology 63,1454-1468
192
Bó & Callejas
Cooper MJ (1974) Control of oestrous cycles of heifers with a synthetic prostaglandin analogue Vet
Rec 95, 200-203
Cooper MJ (1976) The use of cloprostenol ("Estrumate") in the controlled breeding of cattle - An
assessment of European field trials Proceedings of a Symposium Oestrus Synchronisation in
Cattle, Editors: Nancarrow CD, Cox RI, 24-38
Cooper MJ, EA Rowson (1975) Control of the oestrous cycle in Friesian heifers with ICI 80,996 Ann
Biol Anim Bioch Biophys 15, 427-436
Cumming LJ, Knee B, Cumming IA, Lawson RAS, JK Findlay (1976) Evaluation of fertility following the
use of the prostaglandin F2α analogue (Cloprostenol, ICI) in Victorian Herds Proceedings of a
Simposium Oestrus Synchronisation in cattle. Editors: Nancarrow CD, Cox RI, 101-110
Cutaia L, Moreno D, Villata ML, GA Bó (2001) Synchrony of ovulation in beef cows treated with
progesterone vaginal devices and estradiol benzoate administered at device removal or 24 hours
later. Theriogenology 55, 408
Cutaia L, Tríbulo R, Moreno D, GA Bó (2003a) Pregnancy rates in lactating beef cows treated with
progesterone releasing devices, estradiol benzoate and equine chorionic gonadotropin (eCG).
Theriogenology 59, 216
Cutaia L, Veneranda G, Tribulo R, Baruselli PS, GA Bó (2003b) Programas de Inseminación Artificial
a Tiempo Fijo en Rodeos de Cría: Factores que lo Afectan y Resultados Productivos. V° Simposio
Internacional de Reproducción Animal, Huerta Grande, Córdoba, 119-132
Cutaia L, Alisio L, Bertero F, Aviles M, GA Bó (2005) Tasas de preñez en vacas y vaquillonas
sincronizadas con DIB y benzoato de estradiol en el momento del retiro del dispositivo o 24h más
tarde. VI Simposio Internacional de Reproducción Animal, Córdoba, Argentina, 395
De la Sota RL, Risco C, Moreira F, WW Thatcher (1998) Efficacy of a timed insemination program in
lactating dairy cows during summer heat strees Theriogenology 49, 761-770
Ferguson JD, Galligan DR (1983) Prostaglandin synchronization programs in Dairy Herds. Part I,
Compendium on Continuing Education for the Practicing Veterinarian 15, 646-655
Fernandez Francia G, Lares S, Formía N, Giovaninni R, Videla Dorna I, L de la Sota (2005) Eficacia
de la utilización de benzoato de estradiol aplicado a las 0 ó 24 horas del retiro de un dispositivo
intravaginal con progesterona sobre la tasa de preñez en vaquillonas para leche VI Simposio
Internacional de Reproducción Animal, Córdoba, Argentina, 401
Folman Y, Kaim M, Herz Z, M Rosenberg (1990) Comparison of methods for the synchronization of
estrous cycles in dairy cows Effects of progesterone and parity on conception J Dairy Sci 73,
2817-2825
Fortín M (1989) Sincronización de celos en bovinos con prostaglandinas Aspectos prácticos CABIA
15, 29-39
Geary TW, Whittier JC, Hallford DM, MD MacNeil (2001) Calf removal improves conception rates to
the Ovsynch and Co-synch protocols J Anim Sci 79, 1-4.
Ginther OJ, Wiltbank MC, Fricke PM, Gibbons JR, K Kot (1996) Selection of the dominant follicle in
cattle. Biol Reprod 55, 1187-1194
Gumen AJ, Guenther M, MC Wiltbank (2003) Follicular size and response to Ovsynch versus
detection of estrus in anovular and ovular lactating dairy cows J Dairy Sci 86, 3184-3194
Hanlon DW, Williamson NB, Wichtel JJ, Steffert IJ, Craigie AL, DU Pfeiffer (1997) Ovulatory
responses and plasma luteinizing hormone concentrations in dairy heifers after treatment with
exogenous progesterone and estradiol benzoate Theriogenology 47, 963-975
Kastelic JP, OJ Ginther (1991) Factors affecting the origin of the ovulatory follicle in heifers with
induced luteolysis. Anim Reprod Sci 26,13-24
Lamb GC, Stevenson JS, Kesler DJ, Garverick HA, Brown DR, Salfen BE (2001) Inclusion of an
intravaginal progesterone insert plus GnRH and prostaglandin F2α for ovulation control in
postpartum suckled beef cows. J Anim Sci 79, 2253–2259
Lauderdale JW (1975) The use of prostaglandins in cattle Ann Biol Anim Bioch Biophys 15, 419-425
Macmillan KL, WW Thatcher (1991) Effects of an agonist of gonadotropin-releasing hormone on
ovarian follicles in cattle. Biol Reprod 45, 883-889
Macmillan KL, Colson DD, VM Eagles (1999) Modifications to improve whole herd synchrony
programs in seasonal dairy herds. Proc Australian Assoc of Cattle Vet, 121-129
Macmillan KL, AJ Peterson (1993) A new intravaginal progesterone releasing device for cattle (CIDRB) for estrus synchronization, increasing pregnancy rates and the treatment of post-partum
anestrus. Anim Reprod Sci 33, 1-25
Sincronización de celos y ovulaciones
193
Martínez MF, Adams GP, Bergfelt DR, Kastelic JP, RJ Mapletoft (1999) Effect of LH or GnRH on the
dominant follicle of the first follicular wave in beef heifers Anim Reprod Sci 57, 24-33
Martínez MF, Kastelic JP, Adams GP, Cook B, Olson WO, RJ Mapletoft (2002) The use of progestins
for fixed-timed artificial insemination in beef cattle. Theriogenology 57, 1049-1059
Momont HW, BE Seguin (1984) Influence of the day of estrous cycle on response to PGF2α products:
Implications for AI programs for dairy cattle 10th International Congress on Animal Reproduction
3, 336
Moreira F, De La Sota RL, Diaz T, WW Thatcher (2000) Effect of day of the estrous cycle at the
initiation of a timed artificial insemination protocol on reproductive responses in dairy heifers J
Anim Sci 78, 1568-1576
Moreira F, Orlandi C, Risco CA, Mattos R, Lopes F, WW Thatcher (2001) Effects of
presynchronization and bovine somatotropin on pregnancy rates to a timed artificial insemination
protocol in lactating dairy cows J Dairy Sci 84, 1646-1659
Murphy BD, D Martinuk (1991) Equine Chrorionic Gonadotropin Endocrine Reviews 12, 27-44
Nebel RL, SM Jobst (1998) Evaluation of Systematic Breeding Programs for Lactating Dairy Cows: A
Review J Dairy Sci 81, 1169-1174
Odde KG (1990) A review of synchronization of estrus in postpartum cattle J Anim Sci 68, 817-830
Pratt SL, Spitzer JC, Burns GL, BB Plyer (1991) Luteal function, estrus response and pregnancy rate
after treatment with norgestomet and various dosages of estradiol valerate in suckled cows J Anim
Sci 69, 2721-2726
Pursley JR, Mee MO, MC Wiltbank (1995) Synchronization of ovulation in dairy cows using PGF2α
and GnRH. Theriogenology 44, 915-923
Pursley JR, Wiltbank MC, Stevenson JS, Ottobre JS, Garverick HA, LL Anderson (1997) Pregnancy
rates per artificial insemination for cows and heifers inseminated at a synchronized ovulation or
synchronized estrus J Dairy Sci 80, 295-300
Pursley JR, Fricke PM, Garverick HA, Kesler DJ, Ottobre JS, Stevenson JS, MC Wiltbank (2001) NC113 Regional Research Project Improved fertility in noncycling lactating dairy cows treated with
exogenous progesterone during Ovsynch Midwest Branch ADSA 2001 Meeting, Des Moines IA,
63
Revah I, Buttler WR (1996) Prolonged dominance of follicles and reduced viability of bovine oocytes. J
Reprod Fertil 106, 39-47
Ross PJ, Aller JF, Callejas SS, Butler H, RH Alberio (2004) Estradiol benzoate given 0 or 24 h after
the end of a progestagen treatment in postpartum suckled beef cows Theriogenology 62, 265-273.
Sorroarain N, Vaca RJA, Fernández Francia MG, Lares SF, de La Sota RL, A Baldo (2005) eficiencia
de la utilización de benzoato de estradiol a las 0 ó 24 horas del retirado el dispositivo intravaginal
con progesterona para inducir la ovulación en vacas multíparas para carne VI Simposio
Internacional de Reproducción Animal, Córdoba, Argentina, 425
Stevenson JS, Kobayashi Y, KE Thompson (1999) Reproductive performance of dairy cows in various
programmed breeding systems including Ovsynch and combinations of Gonadotropin-Releasing
Hormone and Prostaglandin F2α J Dairy Sci 82, 506-515.
Stock AE, Fortune JE (1993) Ovarian follicular dominance in cattle: relationship between prolonged
growth of the ovulatory follicle and endocrine parameters. Endocrinology 132,1108-1114.
Thatcher WW, Moreira F, Santos JEP, Mattos RC, Lopez FL, Pancarci SM, Risco CA (2001) Effects of
hormonal treatments on reproductive performance and embryo production. Theriogenology 55,
75-90.
Thatcher WW, Bilby TR, Bartolome JA, Silvestre F, Staples CR, Santos JEP (2006) Strategies for
improving fertility in the modern dairy cow Theriogenology 65, 30-44
Torquati O, Barragán M, R Alberio (1983) Uso del cloprostenol para sincronización de celo en cría
cormercial de bovinos Prod Anim 10, 481-489.
Twagiramungu H, Guibault L, Dufour J (1995) Synchronization of ovarian follicular waves with a
Gonadotropin-Releasing Hormone agonist to increase the precision of estrus in cattle: A review J
Anim Sci 73, 3141-3151
Vasconcelos JLM, Silcox RW, Rosa GJ, Pursley JR, MC Wiltbank (1999) Synchronization rate, size of
the ovulatory follicle, and pregnancy rate after synchronization of ovulation beginning on different
days of the estrous cycle in lactating dairy cows Theriogenology 52, 1067-1078
194
Bó & Callejas
Veneranda G, Filippi L, Racca D, Romero G, Balla E, Cutaia L, GA Bo (2006) Pregnancy rates in dairy
cows treated with intravaginal progesterone devices and different fixed-time AI protocols. Reprod
Fert Devel 18,118
Wiltbank JN, Zimmerman DR, Ingalls JE, WW Rowden (1965) Use of progestational compounds alone
or in combination with estrogen for synchronization of estrus J Anim Sci 24, 990-994
Xu Z, Garverick HA, Smith GW, Smith MF, Hamilton SA, RS Youngquist (1995) Expression of folliclestimulationg hormone and luteinizing hormone receptor messenger ribonucleic acids in bovine
follicles during the first follicular wave Biol Reprod 53, 951-957
Yavas Y, JS Walton (2000) Postpartum acyclicity in suckled beef cows: a review Theriogenology 54,
25-55
Sincronización de celos y ovulaciones
195