Período 2000-2005 - Departamento de Quimica Biologica

Transcripción

TRABAJOS PUBLICADOS POR GRUPOS DE INVESTIGACIÓN
DEPARTAMENTO DE QUÍMICA BIOLÓGICA
2000-2005
Laboratorio de Química de Proteoglicanos y Matriz Extracelular (Juan C. Calvo)
Publicaciones
1. Heparin increases the adhesion of murine mammary adenocarcinoma cells (LM3).
Correlation with the presence of heparin receptors on cell surface.
G. Bertolesi, A.M. Eijan, J.C. Calvo, L. Lauria de Cidre.
Journal of Biological Regulators and Homeostatic Agents 19 (1-2): 33-40, 2005
ISSN: 0393-974X
MEDLINE Abbr: J Biol Regul Homeost Agents
NLM Unique ID: 8809253
Place: Italy
2. Further evidence on the role of heparin sulfate as protamine acceptor during the
decondensation of human spermatozoa in vivo.
Marina Romanato, Eleonora Regueira, Mónica S. Cameo, Consuelo Baldini, Lucrecia
Calvo and Juan Carlos Calvo.
Human Reproduction 20 (10): 2784-2789, 2005.
pISSN: 0268-1161
eISSN: 1460-2350
MEDLINE Abbr: Hum Reprod
Publisher: Oxford University Press,
Country: England
JRK: 0.94 JIF: 2.09
3. Exogenous interferon-γ alters murine inner cell mass and trophoblast development.
Effect on the expression of ErbB1, ErbB4 and heparin sulfate proteoglycan (perlecan)
Vanina Fontana, Virginia Choren, Liliana Vauthay, Juan Carlos Calvo, Lucrecia Calvo
and Monica Cameo.
Reproduction 128 (6): 717-725, 2004.
pISSN: 1470-1626
eISSN: 1741-7899
MEDLINE Abbr: Reproduction
Publisher: Published for the Society for Reproduction and Fertility by BioScientifica,
Country: England
JIF: 2.606
4. Circulating immunoglobulins that inhibit the binding of follicle stimulating hormone to
its receptor. A putative diagnostic role in resistant ovary syndrome?
Violeta A. Chiauzzi, M.Sc., Leonardo Bussmann, Ph.D., Juan Carlos Calvo, Ph.D.,
Victoria Sundblad, M.Sc., Eduardo H. Charreau, Ph.D.
Clinical Endocrinology (Oxf) 61 (1): 46-54, 2004.
pISSN: 0300-0664
eISSN: 1365-2265
MEDLINE Abbr: Clin Endocrinol (Oxf)
Publisher: Blackwell Publishing,
Country: England
JRK: 0.76 JIF: 2.38
5. Adrenal gland involvement in the regulation of renal 11ß-hydroxysteroid
dehydrogenase 2.
Marisa Zallocchi, Laura Matkovic, Juan Carlos Calvo and María Cristina Damasco.
Journal of Cellular Biochemistry 92 (3): 591-602, 2004.
pISSN: 0730-2312
eISSN: 1097-4644
MEDLINE Abbr: J Cell Biochem
Publisher: Liss,
Country: United States
JRK: 0.79 JIF: 3.47
6. ErbB2 and EGFR are downmodulated during the differentiation of 3T3-L1
preadipocytes.
Eleonora Pagano and Juan Carlos Calvo
Journal of Cellular Biochemistry 90(3):561-72, 2003.
pISSN: 0730-2312
eISSN: 1097-4644
Publisher: Liss,
JRK: 0.79 JIF: 3.47
7. TRPC3-like protein is involved in the capacitative cation entry induced by 1α,25dihydroxy-vitamin D3 in ROS17/2.8 osteoblastic cells.
Baldi Carolina, Vazquez Guillermo, Calvo Juan Carlos and Boland Ricardo.
Journal of Cellular Biochemistry 90:197-205, 2003.
pISSN: 0730-2312
eISSN: 1097-4644
Publisher: Liss,
JRK: 0.79 JIF: 3.47
8. Heparan sulphate: a putative decondensing agent for human spermatozoa in vivo.
Romanato M, Cameo Mónica S, Bertolesi GE, Baldini C, Calvo JC and Calvo L.
Human Reproduction 18: 1868-1873, 2003. Nota: en el manuscrito figura que JCC y LC
tuvieron igual participación en el diseño experimental y en la confección del manuscrito.
La ubicación de los autores fue decisión personal.
pISSN: 0268-1161
eISSN: 1460-2350
MEDLINE Abbr: Hum Reprod
Publisher: Oxford University Press,
Country: England
JRK: 0.94 JIF: 2.09
9. Mechanisms of brush border Na+/H+ exchanger activation by corticosteroids.
Marisa Zallocchi, Pilar Igarreta, Juan Carlos Calvo, Nancy Amaral Reboucas, María
Cristina Damasco.
Medical Science Monitor 9 (2): 85-90, 2003.
pISSN: 1234-1010
eISSN: 1643-3750
MEDLINE Abbr: Med Sci Monit
Publisher: Medical Science International,
Country: Poland
10. Effect of Leptin on progesterone, human Chorionic Gonadotropin (hCG) and
Interleukin-6 (IL-6) secretion by human term trophoblast cells in culture.
Paula Cameo, Paul Bischof, Juan Carlos Calvo.
Biology of Reproduction 68: 472-477, 2003.
pISSN: 0006-3363
eISSN: 1529-7268
MEDLINE Abbr: Biol Reprod
Publisher: Society for the Study of Reproduction
JRK: 0.82 JIF: 2.81
11. Changes in IGF-I receptor and IGF-I mRNA during differentiation of 3T3-L1
preadipocytes.
Cynthia F. Zizola, María E. Balañá, Marcela Sandoval, Juan C. Calvo.
Biochimie 84: 975-980, 2002.
ISSN: 0300-9084
MEDLINE Abbr: Biochimie
Publisher: Editions Scientifiques Elsevier
Country: France
JRK: 0.49 JIF: 1.57
12. Heparin and heparinase activity detection on polyacrylamide gel electrophoresis
using the fluorochrome tris (2,2’-bipyridine) ruthenium (II).
Gabriela I. Rozenberg, Jesús Espada, Lilia Lauria de Cidre, Ana M Eiján, Juan C. Calvo
and Gabriel E. Bertolesi.
Electrophoresis 22: 3-11, 2001.
ISSN: 0173-0835
MEDLINE Abbr: Electrophoresis
Publisher: Vch Publishers
Country: Germany
JRK: 0.91 JIF: 2.63
13. Autoinmunidad y falla ovárica.
Charreau, E.H.; Chiauzzi, V.; Bussmann, L.; Calvo, J.C.; Cortelezzi, M.; del Castillo, E.
La Prensa Médica Argentina 87: 624-629, 2000.
pISSN: 0032-745X
MEDLINE Abbr: Prensa Med Argent
Publisher: Prensa Medica Argentina
Country: Argentina
14. Kinetic properties of microsomal 3β hydroxysteroid dehydrogenase-isomerase from
the testis of Bufo arenarum H.
AG Pozzi, LF Canosa, JC Calvo, NR Ceballos.
Journal of Steroid Biochemistry and Molecular Biology 73: 257-264, 2000.
ISSN: 0960-0760
MEDLINE Abbr: J Steroid Biochem Mol Biol
Publisher: Pergamon Press
Country: England
JRK: 0.79 JIF: 1.74
Artículos de divulgación científica
1. Calvo J.C. Evaluación de un sistema hormona-receptor. Separata 2004: Fisiología
Endocrina. Bioquímica y Métodos Diagnósticos. Fascículo II. 54-59. Directores: M. A.
Pisarev y R. S. Calandra. Coordinadores: M.O. Suescun y G.J. Juvenal. ISSN 1515-3878.
Publicada por Química Montpellier S.A. Buenos Aires, Argentina.
2.
Calvo
J.C.
El
círculo
de
la
vida.
Revista
QuímicaViva
Número 1, año 3, abril 2004 Número especial: la clonación humana. Recuperable de
http://www.quimicaviva.qb.fcen.uba.ar ISSN 1666-7948
3. Calvo J.C. Una nueva visión del ARN: los ARN de interferencia. ¿Un nuevo genoma?
QuímicaViva (QV) 2003; 2 (3). Recuperable de http://www.quimicaviva.qb.fcen.uba.ar
ISSN 1666-7948
4. Calvo J.C. Proteínas a medida. QuímicaViva (QV) 2003; 2 (2). Recuperable de
http://www.quimicaviva.qb.fcen.uba.ar ISSN 1666-7948
5. El Genoma Humano: ¿un libro abierto o un rompecabezas para armar? Juan Carlos
Calvo. Ciencia e Investigación 54, 9-17, 2002 ISSN-0009-6733
Laboratorio de Bioquímica y biología del virus Junín en infecciones agudas y
persistentes (Nélida Candurra)
Publicaciones
1. Probing the interaction between vesicular stomatitis virus and phosphatidylserine.
Carneiro, F.; Lapido-Loureiro, P.; Cordo, S. M.; Stauffer, F.; Weissmüller, G.; Bianconi,
M. L.; Juliano, M.; Juliano, L.; Bisch, P.; Da Poian, A Special issue of European
Biophysical Journal entitled Biophysics meets Molecular Medicine. Manuscript No.
EBJ-05-0050.R1. En prensa
2. Inhibition of cell fusion in Junin virus-infected cells by sera from Argentine
hemorrhagic fever patients. Castilla, V.; Contigiani, M.; Mersich, S. E. Journal of
Clinical Virology. 32: 286-288, 2005 .
3. Polarized entry and release of Junín virus, a New Word arenavirus. Cordo, S. M.;
Cesio y Acuña, M.; Candurra, N. A. Journal of General Virology 86: 1475-1479, 2005.
4. Resistance to superinfection of Vero cells persistently infected with Junin virus.
Ellenberg, P. C.; Edreira, M.; Scolaro, L.A. Archives of Virology 149: 507-522, 2004
5. Intermediate filament integrity is required for Junin virus replication. Sandra M
Cordo, Nélida A. Candurra. Virus Research, 97: 47-55, 2003.
6. Synthesis and expression of viral antigens in Vero cells persistently infected with Junin
virus. Ellenberg PC, Edreira MM, Lozano ME, Scolaro LA. Arch Virol. 147 (8):1543-57,
2002.
7. Effect of fatty acids on arenavirus replication: inhibition of virus production by lauric
acid. S. Bartolotta, C. C. García, N. A. Candurra, E .B. Damonte. Archives of Virology,
146: 777-790, 2001.
Libros
Candurra, N. A.; Coto, C. E. Cultivos celulares: qué saber y qué hacer. Editado por la
Federación Bioquímica de la Provincia de Buenos Aires como suplemento del Acta
Bioquímica Clínica Latinoamericama. En prensa.
 Scolaro, L. A., Claus J. D. Capítulo 8. Control de calidad de los cultivos celulares.
 Nélida A. Candurra, Sandra .M. Cordo, Erina Petrera y Luis A. Scolaro. Capítulo
15.Protocolos
 Candurra N. A. Capítulo 6: Características de los cultivos celulares. Capítulo 7:
Técnicas generales de cultivo. Capítulo 13: Diagnóstico Virológico
Capítulos de libros
Microbiología Biomédica, Editorial Atlante, Buenos Aires, Argentina. Editor: Celia E.
Coto, Ramón de Torres y Juan A. Basualdo. Segunda edición. ISBN: 950-9539-30-9 En
prensa.
 Weber, L.; Scolaro, L. A. Agentes infecciosos no convencionales.
 Castilla, V; Enría, D. Arenaviridae.
 Candurra, N. A. Cultivo de virus
Laboratorio de Biología Molecular: Regulación de la expresión génica y control del
ciclo celular (Eduardo T. Cánepa)
Publicaciones
1. “Cell growth-dependent subcellular localization of p8”
María P. Valacco, Cecilia L. Varone, Cedric Malicet, Eduardo T. Cánepa, Juan L.
Iovanna, and Silvia Moreno
J. Cell. Biochem. 97 (2006), 1066-1079.
2. “Induction of p19INK4d in response to ultraviolet light improves DNA repair and
confers resistance to apoptosis in neuroblastoma cells”
Julieta M. Ceruti, María E. Scassa, Juan M. Fló, Cecilia L. Varone, and Eduardo T.
Cánepa
Oncogene 24 (2005), 4065-4080.
3. “Repression of 5-aminolevulinte synthase gene by the potent tumor promoter, TPA,
involves multiple signal transduction pathways”
Alejandra S. Guberman, María E. Scassa, and Eduardo T. Cánepa
Arch. Biochem. Biophys. 436 (2005), 285-296.
4. “Hepatic nuclear factor 3 and nuclear factor 1 regulate 5-aminolevulinate synthase
gene expression and are involved in insulin repression”
María E. Scassa, Alejandra S. Guberman, Julieta M. Ceruti, and Eduardo T. Cánepa
J. Biol. Chem. 279 (2004), 28082-28092.
5. “Inhibitory effect of AP-1 complex on 5-aminolevulinate synthase gene expression
through sequestration of CBP coactivator”
Alejandra S. Guberman, María E. Scassa, Luciana E. Giono, Cecilia L. Varone, and
Eduardo T. Cánepa
J. Biol.. Chem. 278 (2003), 2317-2326
6. “Phosphatidylinositol 3-kinase and Ras/Mitogen activated protein kinase signaling
pathways are required for the regulation of 5-aminolaevulinate synthase gene expression
by insulin”
María E. Scassa, Alejandra S. Guberman, Cecilia L. Varone and Eduardo T. Cánepa
Exp. Cell Res. 271 (2001), 201-213.
7. “TGFβ-1 enhances the Smad transcriptional activity through activation of p8 gene
expression”.
Andrés G. Montero, Sophie Vasseur, Luciana Giono, Eduardo Cánepa, Silvia Moreno, Jean
Dagorn and Juan Iovanna.
Biochem. J. 357 (2001), 249-253
8. “Human p8 is a HMG-I(Y)-like protein with DNA binding activity enhanced by
phosphophorylation”
José Encinar, Gustavo Mallo, Cynthia Mizyrycki, Luciana Giono, José González-Ros,
Manuel Rico, Eduardo Cánepa, Silvia Moreno, José Neira and Juan Iovanna.
J. Biol. Chem. 276 (2001), 2742-2751.
9. “5-aminolaevulinate synthase gene promoter contains two cAMP-response element
(CRE)-like sites that confer positive and negative responsiveness to CRE-binding protein
(CREB)”
Luciana E. Giono, Cecilia L. Varone and Eduardo T. Cánepa
Biochem J. 353 (2001), 307-316.
Laboratorio de Regulación génica en levaduras (Susana Correa)
Publicaciones
1. Bermúdez Moretti, M., Perullini AM., Batlle A and Correa García S. Expression of the
UGA4 gene encoding the δ-aminolevulinic and γ-aminobutyric acids permease in
Saccharomyces cerevisiae is controlled by amino acid-sensing systems.
Archives of Microbiology, 2005. En prensa.
2. S. Correa García, A. Casas, C. Perotti, A. Batlle and M. Bermúdez Moretti.
Mechanistic studies on δ-aminolevulinic acid uptake and efflux in a mammary
adenocarcinoma cell line.
British Journal of Cancer 89, 173-177, 2003.
3. M. Bermúdez Moretti*, S. Correa García*, C. Perotti, A. Batlle and A. Casas.δaminolevulinic acid transport in murine mammary adenocarcinoma cells is mediated by
BETA transporters.
British Journal of Cancer 87, 471-474, 2002.
* MBM and SCG contributed equally to this work.
4. M. Bermúdez Moretti, A. Batlle and S. R. Correa García. UGA4 gene encoding the γaminobutyric acid permease in Saccharomyces cerevisiae is an acid expressed gene.
Int. J. Biochem. Cell Biol. 33 (12), 1202-1207, 2001.
5. M. Bermúdez Moretti, S. Correa García and A. Batlle. Porphyrin biosynthesis
intermediates are not regulating δ-aminolevulinic acid transport in Saccharomyces
cerevisiae.
Biochem. Biophys. Res. Comm. 272 (3) 946-950, 2000.
6. Susana R. Correa García, Mariana Bermúdez Moretti and A. Batlle. The constitutive
expression of UGA4 gene in Saccharomyces cerevisiae depends on two positive-acting
proteins, Uga3p and Uga35p.
FEMS Microbiology Letters. 184, 219-224, 2000.
Laboratorio de Biosensores y bioanálisis (Eduardo Cortón)
Publicaciones
1. Learning Stoichiometry with Hamburger Sandwiches. Liliana Haim, Eduardo Cortón,
Santiago Kocmur, and Lydia Galagovsky. J. Chemical Education, 2003, 80, 1021.
2. Rapid identification of viable Escherichia coli subspecies with an electrochemical
screen-printed biosensor array. Peter Ertl, Melany Wagner, Eduardo Cortón, Susan R.
Mikkelsen. Biosensors and Bioelectronics, 2003, 18, 907-916.
3. Use of a CO2 electrode to monitor fermentations that use xenobiotic compound as
source of carbon. P. Englebienne, M.G. López, E. Cortón and A. A. Viale. Revista
Argentina de Microbiología, 2002, 34, 74-76.
4. A Non-radioctive Simulation of the Viking Mission Labeled Released (LR)
Experiment: A Search for Evidence of Life. Eduardo Cortón, Liliana Haim, Santiago
Kocmur, Guillermo J. Visbeek and Lydia A. Galagovsky. J. Chemical Education, 2002,
79, 1105-1108.
5. Effect of milk proteins on the behavior of a biosensor based on poly(allylamine)
containing an osmium complex wired to redox enzymes. 2. Bienzymatic Configuration.
Eduardo Cortón y Fernado Battaglini. J. Electroanalytical Chemistry, 2001, 511, 08-12.
6. Effect of milk proteins on the behavior of a biosensor based on poly(allylamine)
containing an osmium complex wired to redox enzymes. 1. Monoenzymatic
Configuration. Eduardo Cortón y Fernado Battaglini. J. Electroanalytical Chemistry,
2001, 511, 01-07.
7. A Novel Electrochemical Method for the Identification of Microorganisms, Eduardo
Cortón, Diego Raffa, and Susan R. Mikkelsen. Electroanalysis, 2001, 13, 999-1002.
8. Potentiometric Determination of CO 2 Concentration in the Gaseous Phase:
Applications in Different Laboratories Activities. Eduardo Cortón, Santiago Kochmur,
Liliana Haim and Lydia A. Galagovsky. J. Chemical Education, 2000, 77, 1188-1191.
9. Characterization of Lactobacillus Carbohydrate Fermentation Activity Using
Immobilized Cell Technique. Eduardo Cortón, Mariana Piuri, Fernando Battaglini and
Sandra M. Ruzal. Biotechnol. Progress, 2000, 16, 59-63.
1. Ruedas Terrestres sobre Otros Mundos. Eduardo Cortón. Ciencia Hoy, 2002, 12, 1217.
2. La Búsqueda de Vida en Marte. Eduardo Cortón. Ciencia Hoy, 2000, 10, 58-66.
Libros
1. Química Bioanalítica. Traducción realizada por el autor hispano-parlante (EC) de la
obra “Bioanalytical Chemistry”, versión en castellano terminada al 10/05, esta siendo
evaluada por McGraw-Hill para su publicación en América y España. Susan R.
Mikkelsen y Eduardo Cortón
2. Bioanalytical Chemistry. Susan R. Mikkelsen and Eduardo Cortón. Junio 2004, WileyInterscience, ISBN 0-471-62386-5. Edición electrónica, Libro de texto, 384 paginas
3. Bioanalytical Chemistry. Susan R. Mikkelsen and Eduardo Cortón. Febrero 2004,
Wiley-Interscience, ISBN 0-471-54447-7. Libro de texto, 384 paginas.
4. Problemática Ecológica y Ambiental. Capítulo denominado “Ecología del Ecosistema
Antártico y de las Regiones Polares, páginas 209-222, por Hernán Sala y Eduardo
Cortón. Editores José Luis Parada, Fernando H. Larrumbe y Eduardo A. Baldi. Editorial
Dunken, 2004, 408 páginas. ISBN 987-21290-0-2, primera edición.
5. Temas de Ecología. Volumen 3. Eduardo Cortón y Elizabeth Robello. Editora
Universidad Libros, Bs. As., Argentina, 2001, ISBN 987-9465-24-5, Primera Edición
2000 ejemplares. 68 pp.
6. Temas de Ecología. Volumen 2. Eduardo Cortón y Liliana Richner. Editora
Universidad Libros, Bs. As., Argentina, 2000, ISBN 987-9465-14-8, Primera edición
7. Temas de Ecología. Volumen 1. Eduardo Cortón y Liliana Richner. Editora
Universidad Libros, Bs. As., Argentina, 2000, ISBN 987-98030-1-9, Primera Edición
Laboratorio de Virología: Agentes antivirales y citotóxicos (Laura Alché y Celia
Coto)
Publicaciones
1.
“Synergistic in vitro interactions between (22S,23S)-3β-bromo-5α,22,23trihydroxystigmastan-6-one and foscarnet against herpes simples virus type 1”.
Laura B. Talarico, Viviana Castilla, Javier A. Ramírez, Lydia R. Galagovsky and Mónica
B. Wachsman. Chemotherapy 52: 38-42, (2006).
2. “Antiviral mode of action of a synthetic brassinosteroid against Junín virus
replication”. Viviana Castilla, Mariano Larzábal, Natalia Aguirre Sgalippa, Mónica B.
Wachsman and Celia E. Coto. Antiviral Research 68: 88-95, (2005).
3. A Simple Laboratory Exercise for Etanol Production by Immobilized Bakery
Yeasts (Saccharomyces cerevisiae). Diana L. Vullo and Mónica B. Wachsman
Journal of Foof Science Education 4: 53-55, (2005).
4. “An antibacterial and antiviral peptide produced by Enterococcus mundii ST4V
isolated from soy beans”. Todorov Svetoslav D, Wachsman Mónica B., Knoetze
Hendriette, Meincken Martina and Dicks Leon M. T. International Journal of.
Antimicrobial Agents 25: 508-513, (2005).
5. “In vitro and in vivo antiherpetic activity of three new synthetic brassinosteroid
analogues”. Michelini F., Ramírez J., Berra A., Galagovsky L. and Alché L.. Steroids 69:
713-720 (2004).
6. “Antiviral Activity of Natural and synthetic Brassinosteroids”. Wachsman, Monica B.,
Ramirez Javier A., Talarico Laura B., Galagovsky Lydia R., Coto Celia E. Current
Medicinal Chemistry – Antiinfective Agents 3: 163-179, (2004).
7. “Antiviral activity of antimicrobial cationic peptides against Junin virus and herpes
simplex virus”. V.C.Albiol Matanic and V. Castilla. International Journal of.
Antimicrobial Agents 23: 382-389, (2004).
8. “Block of VSV endocytic and exocytic pathways by 1- cinnamoyl-3,11dihydroxymeliacarpin, a tetranortriterpenoid of natural origin”. Andrea A. Barquero,
Laura E. Alché and Celia E. Coto. Journal of General Virology 85: 483-493 (2004).
9. “Antiherpetic mode of action of (22S,23S)-3β-bromo-5α,22,23-trihydroxystigmastan
6-one in-vitro”. Wachsman MB, Castilla V, Talarico LB, Ramirez JA, Galagovsky LR,
Coto CE. International Journal of. Antimicrobial Agents, 23: 525-527, (2004).
10. “Enterocin CRL35 inhibits late stages of HSV-1 and HSV-2 in vitro multiplication”.
Mónica B. Wachsman, Viviana Castilla, Aida P. De Ruiz Holgado, Ramón A. de Torres.
Fernando Sesma and Celia E. Coto.
Antiviral Research 58: 17-24, (2003).
11. “Antiherpes virus activity of new 6-19 carbon-bridged steroids and some synthetic
precursors”. Petrera, E., Joselevich, M., Ghini, A., Burton, G. and Coto C.E. Antiviral
Chemistry and Chemotherapy. 14: 243-248, (2003).
12. “Effect of meliacine, a plant derived antiviral, on tumor necrosis factor alpha”.
Petrera, E and Coto C.E. Fitoterapia 74: 77-83, (2003).
13. “Hippocampal infection with HSV-1-derived vectors expressing an NMDAR1
antisense modifies behavior”. M. F. Adrover, V. Guyot-Revol, V. T. Cheli, , C. Blanco,
R. Vidal, L. Alché, E. Kornisiuk, A. L. Epstein and D. Jerusalinsky. Genes, Brain and
Behavior 2: 103-13, (2003).
14. “An antiviral meliacarpin from leaves of Melia azedarach L.”. Alché L.E., Assad
Ferek G., Meo M., Coto C.E. and Maier, M.S.. Zeitschrift für Naturforschung Section C
58c (3/4): 215-219 (2003).
15. “Structure-activity relationship studies in a set of new brassinosteroid derivatives
assayed against herpes simples virus type 1 and 2 in cell cultures”
Talarico Laura B., Ramirez Javier A., Galagovsky Lydia R. and Wachsman Mónica B.
Medicinal Chemistry Research, 11: 434-444, (2002).
16. “Gene transfer of NMDAR1 subunit sequences to the rat CNS using Herpes Simplex
Virus vectors interfered with habituation”.V. T. Cheli, M. F. Adrover, C. Blanco, E. Rial
Verde, V. Guyot-Revol, R. Vidal, E. Martin, L. Alché, G. Sanchez, M. Acerbo, A. L.
Epstein and D. Jerusalinsky. Cellular and Molecular Neurobiology 22: 303-14 (2002).
17. “Therapeutic action of meliacine, a plant-derived antiviral, on HSV-induced ocular
disease in mice”.María Paula Pifarré, Alejandro Berra, Celia E. Coto and Laura E.
Alché. Experimental Eye Research 75: 327-334, (2002).
18. “An antiviral principle present in a purified fraction from Melia azedarach L. leaf
aqueous extract restrains Herpes simplex virus type 1 propagation”. Laura E. Alché,
Andrea A. Barquero, Norberto A. Sanjuan and Celia E. Coto. Phytotherapy Research 16:
348-352, (2002).
19. “Antiviral activity of brassinosteroid derivatives against Measles virus replication”.
Mónica B. Wachsman, Javier A. Ramírez and Lydia Galagovsky. Antiviral Chemistry
and Chemotherapy 13: 61-66, (2002).
20. “Actividad antiviral en productos naturales: Melia azedarach L. Efecto sobre la
multiplicación del virus Junín, agente de la fiebre hemorrágica argentina y acción
terapéutica sobre la queratitis estromal del ratón causada por herpes simplex.” Celia E.
Coto, Laura E. Alché, Viviana Castilla. Anales Academia Nacional de Ciencias Exactas,
Físicas y Naturales 53: 161-177, (2001).
21. “Involvement of vacuolar proton ATPase on Junin virus multiplication.”
Viviana Castilla, Laura M. Palermo, Celia .E. Coto.
Archives of Virology 146: 251-263, (2001).
22. “Effective treatment of mouse herpetic stromal keratitis with meliacine, a plantderived antiviral”. Laura E. Alché, Alejandro Berra and Celia E. Coto. International
Antiviral News 9: 132-135, (2001). Publicado por invitación del Dr. Derek Kinchington,
Scientific Writer/Editor International Medical Press.
23. "Antiviral effect of brassinosteroids against herpes and arenaviruses”..
Mónica B. Wachsman, Elsa M.F. López, Javier A. Ramirez, Lydia R. Galagovsky y Celia
E. Coto. Antiviral Chemistry and Chemotherapy 11: 71-77, (2000).
24. “Treatment with meliacine, a plant derived antiviral, prevents the development of
herpetic stromal keratitis in mice”. Alché L.E., Berra A., Veloso M.J. and Coto C.E.
Journal of Medical Virology 61: 474-480, (2000).
Laboratorio de Apoptosis y virus (Susana Mersich y Félix Coulombié)
Publicaciones
1. Título: Oxidative stress in Vero cells infected with Vesicular Stomatitis virus.
Año: 2005. Aprobado para su publicación En pruebas de galera.
País: Suiza.
Nombre: Intervirology.
ISBN: 0304-8608.
Idioma : Inglés.
Autores: Riva D, Ríos de Molina MC , Rocchetta I, Gerhardt E, Coulombié F, Mersich S.
2. Título: Inhibition of cell fusion in Junín-virus infected cells by sera from Argentine
Hemorrhagic fever patients.
Año: 2005.
País: Holanda.
Nombre: Journal of Clinical Virology. 32:286-288.
ISBN: 1386-6532.
Idioma: Inglés.
Autores: Castilla V, Contigiani M, Mersich S.
3. Título: Early activation of the mitochondrial apoptotic pathway in Vesicular Stomatitis
virus-infected cells.
Año: 2004.
País: Holanda
Nombre de la revista: Virus Research. 109:65-69.
ISBN: 0168-1702
Idioma: Inglés.
Autores: Gadaleta P, Perfetti X, Mersich S, Coulombié F.
4. Título: Influenza circulating strains exhibit differential induction of cytotoxicity and
caspase-3 in vitro.
Año: 2004.
País: Holanda.
Nombre de la revista: Journal of Clinical Virology. 31:134-139.
ISBN: 1386-6532.
Idioma: Inglés.
Autores: Mersich S, Baumeister E, Riva D, Lewis A, Cadario S, Pontoriero A, Savy V.
5. Título: Virucidal activity activity present in Trichilia glabra leaves.
Año: 2004
País: Argentina.
Nombre de la revista: Revista Argentina de Microbiología. 36: 136-138.
ISBN: 0325-7541.
Idioma: Inglés. ( Artículos preferentemente en Castellano)
Autores: Cella M, Riva D, Coulombié F, Mersich S.
6. Título: Vesicular stomatitis virus induces apoptosis at early stages in the viral cycle
and does not depend on virus replication.
Año: 2002
País: Holanda.
Nombre de la revista: Virus Research 86(1-2): 87-92.
ISSN: 0168-1702.
Idioma: Inglés.
Autores: Gadaleta P. , Vacotto M., Coulombié P.
7. Título: Antiviral activity of an acidic polysaccharides fraction extracted from Cedrela
tubiflora leaves.
Año: 2001
País: Holanda
Nombre de la revista: Fitoterapia 72(2): 113-9.
ISSN: 0367-326X
Idioma: Inglés.
Autores: Craig MI, Benencia F., Coulombié F.
8. Título: In vivo and in vitro immunomodulatory activities of Trichilia glabra aqueous
leaf extracts.
Año: 2000
País: Irlanda
Nombre de la revista: J. Ethnopharmacology 69(3): 199-205.
ISSN: 0378-8741
Idioma: Inglés.
Autores: Benencia F, Courreges MC, Coulombié F.
9. Título: Anti-inflammatory activities of Trichilia glabra aqueous leaf extract.
J Ethnopharmacol. 2000 Jul;71(1-2):293-300.
Año: 2000
País: Irlanda
Nombre de la revista: J. Ethnopharmacology 71(1-2): 293-300.
ISSN: 0378-8741
Idioma: Inglés.
Autores: Benencia F, Courreges MC, Coulombié FC.
1. Título del Libro: Microbiología Biomédica. Unico libro de texto de origen
Latinoamericano que forma parte del PAL:TEX. Programa ampliado de Libros de Texto
y materiales de instrucción de la OPS, en Area de Microbiología.
Título: Respuesta inmune y Patogenia. Cap 64.
Año: 2005. (en prensa). Reedición actualizada de 1996.
País: Argentina. Editorial Atlante. Buenos Aires. Ed. J. Basualdo y R. de Torres.
ISBN: 950-9539-30-9
Autores: Coulombié, F.
2. Título del Libro: Microbiología Biomédica.
Título: Agentes inactivantes de virus. Cap 63.
ISBN: 950-9539-30-9
Autores: Mersich, S.
3. Título del Libro: Microbiología Biomédica.
Título: Genética de virus Animales. Cap. 62.
ISBN: 950-9539-30-9
Autores: Damonte E, Mersich S.
Otros Trabajos
1. Título: Nuevas estrategia terapéuticas basadas en apoptosis y virus.
Año: 2003
País: Argentina.
Nombre de la revista: Acta de Bioquímica Clínica Latinoamericana. 2003. 37:13-19.
Gráfico incluido en la tapa del ejemplar 37.
ISBN: Castellano ISSN 0325/2957
Idioma: Castellano
Autores: Gadaleta P, Mersich S.
2. Título: Vaccine production in Argentina: a decision that cannot be postponed
Año: 2003.
País : Argentina
Nombre de la revista: Medicina (B Aires). 2003;63(5):457-8.
ISSN: Desconocido
Idioma. Español.
Autores: Airaldi , MG, ......, Gadaleta P. et al
3. Título: La apoptosis en las infecciones virales en humanos.
Año: 2000.
País: Argentina.
Nombre de la revista: Reseñas de Infectología y Vacunas. (Bs.As).Vol 7, 11-17
ISSN desconocido
Idioma: Castellano
Autores: Mersich S.
Laboratorio de Virología: Estrategias antivirales (Elsa Damonte)
Publicaciones
1. M.C. Rodríguez, E.R. Merino, C.A. Pujol, E.B. Damonte, A.S. Cerezo, M.C.
Matulewicz. Galactans from cystocarpic plants of the red seaweed Callophylis variegata
(Kallymeniaceae, Gigartinales). Carbohydrate Research, 2005 (en prensa).
2. P.C. de S.F-Tischer, L.B. Talarico, M.D. Noseda, S.M.P.B. Guimaraes, E.B.
Damonte, M.E.R. Duarte. Chemical strcuture and antiviral activity of carrageenans from
Meristiella gelidium against herpes simplex and dengue virus. Carbohydrate Polymers,
2005 (en prensa).
3. C.A. Pujol, L.A. Scolaro, M. Ciancia, M.C. Matulewicz, A. Cerezo, E.B. Damonte.
Antiviral activity of a carrageenan from Gigartina skottsbergii against intraperitoneal
murine herpes simplex virus infection. Planta Medica, 2005 (en prensa).
4. B. Matsuhiro, A.F. Conte, E.B. Damonte, A.A. Kolender, M.C. Matulewicz, E.G.
Mejías, C.A. Pujol, E.A. Zúñiga. Structural analysis and antiviral activity of a sulfated
galactan from the red seaweed Schizymenia binderi (Gigartinales, Rhodophyta).
Carbohydrate Research 340: 2392-2402, 2005.
5. C.B. Duschatzky, M.L. Possetto, L.B. Talarico, C.C. García, F. Michis, N.V.
Almeida, M.P. de Lampasona, C. Schuff, E.B. Damonte. Evaluation of chemical and
antiviral properties of essential oils from South American plants. Antiviral Chemistry
and Chemotherapy 16: 247-251, 2005.
6. M.A. Martins Alho, M.I. Errea, V.L. Sguerra, N.B. D’Accorso, L.B. Talarico, C.C.
García, E.B. Damonte. Synthesis and antiviral evaluation of some carbonucleoside
analogues. Journal of Heterocyclic Chemistry 42: 979-983, 2005.
7. L.B. Talarico, C.A. Pujol, R.G.M. Zibetti, P.C.S. Faría, M.D. Noseda, M.E.R. Duarte.
E.B. Damonte. The antiviral activity of sulfated polysaccharides against dengue virus is
dependent on virus serotype and host cell. Antiviral Research 66: 103-110, 2005.
8. P. Ghosh, U. Adhikari, P.K. Ghosal, C.A. Pujol, M.J. Carlucci, E.B. Damonte, B.
Ray. In vitro anti-herpetic activity of sulfated polysaccharide fractions from Caulerpa
racemosa. Phytochemistry 65: 3151-3157, 2004.
9. M.J. Carlucci, L.A. Scolaro, M.D. Noseda, A.S. Cerezo, E.B. Damonte. Protective
effect of a natural carrageenan on genital herpes simplex virus infection in mice.
Antiviral Research 64: 137-141, 2004.
10. L.A. Scolaro, C.A. Pujol, M.J. Carlucci, E.B. Damonte. Perspectivas de los
carragenanos para la prevención de enfermedades de transmisión sexual. Sociedad
Iberoamericana de Información Científica, recuperable de <http:// www.siicsalud.com/
dato/dat039/ 04823000.htm, SIIC Salud, 2004.
11. L.B. Talarico, R.G.M. Zibetti, P.C.S. Faria, L.A. Scolaro, M.E.R. Duarte, M.D.
Noseda, C.A. Pujol, E.B. Damonte. Anti-herpes simplex virus activity of sulfated
galactans from the red seaweeds Gymnogongrus griffithsiae and Cryptonemia crenulata.
International Journal of Biological Macromolecules 34: 63-71, 2004.
12. M.E.R. Duarte, J.P. Cauduro, D.G. Noseda, M.D. Noseda, A.G. Goncalvez, C.A.
Pujol, E.B. Damonte, A.S. Cerezo. The structure of the agaran sulfate from Acantophora
spicifera (Rhodomelaceae, Ceramiales) and its antiviral activity. Relation between
structure and antiviral activity in agarans. Carbohydrate Research 339: 335-347, 2004.
13. C.C. García, L. Talarico, N. Almeida, S. Colombres, C. Duschatzky, E.B. Damonte.
Virucidal activity of essential oils from aromatic plants of San Luis, Argentina.
Phytotherapy Research 17: 1073-1075, 2003.
14. C.C. García, B.N. Brousse, M.J. Carlucci, A.G. Moglioni, M. Martins Alho, G.Y.
Moltrasio, N.B. D’Accorso, E.B. Damonte. Inhibitory effect of thiosemicarbazone
derivatives on Junin virus replication in vitro. Antiviral Chemistry and Chemotherapy
14: 99-105, 2003.
15. G.A. Garrido Santos, A.P. Murray, C.A. Pujol, E.B. Damonte, M.S. Maier.
Synthesis and antiviral activity of sulfated and acetylated derivatives of 2β,3αdihydroxy-5α-cholestane. Steroids 68: 125-132, 2003.
16. C.C. García, N.A. Candurra, E.B. Damonte. Differential inhibitory action of two
azoic compounds against arenaviruses. International Journal of Antimicrobial Agents
21: 319-324, 2003.
17. N.M.A. Ponce, C.A. Pujol, E.B. Damonte, M.L. Flores, C.A. Stortz. Fucoidans from
the brown seaweed Adenocystis utricularis: extraction methods, antiviral activity and
structural studies. Carbohydrate Research 338: 153-165, 2003.
18. R. Torres, B. Modak, A. Urzúa, F. Delle Monache, E. Damonte, C.A. Pujol.
Propiedades antivirales de compuestos naturales y semi-sintéticos de la resina de
Heliotropim filifolium. Bolsín de la Sociedad Chilena de Química 47: 259-263, 2002.
19. S. Mazunder, P.K. Ghosal., C.A. Pujol, M.J. Carlucci, E.B. Damonte, B. Ray.
Isolation, chemical investigation and antiviral activity of polysaccharides from
Gracilaria corticata (Gracilariaceae, Rhodophyta). International Journal of Biological
Macromolecules, 31: 87-95, 2002.
20. C.C. García, N.A. Candurra, E.B. Damonte. Mode of inactivation of arenaviruses by
disulfide-based compounds. Antiviral Research 55: 437-446, 2002.
21. C.A. Pujol, J. Estévez, M.J. Carlucci, M. Ciancia, A. Cerezo, E.B. Damonte. Novel
DL-galactan hybrids from the red seaweed Gymnogongrus torulosus are potent
inhibitors of herpes simplex virus and dengue virus. Antiviral Chemistry and
Chemotherapy 13: 83-89, 2002.
22. M.J. Carlucci, L.A. Scolaro, E.B. Damonte. Herpes simplex virus type 1 variants
arising after selection with an antiviral carrageenan: lack of correlation between drugsusceptibility and syn phenotype. Journal of Medical Virology 68: 82-91, 2002.
23. C.C. García, M.L. Rosso, M.D. Bertoni, M.S. Maier, E.B. Damonte. Evaluation of
the antiviral activity against Junin virus of macrocyclic trichothecenes produced by the
hypocrealean epibiont of Baccharis coridifolia. Planta Medica 68: 209-212, 2002.
24. M.S. Maier, A.J. Roccatagliata, A. Kuriss, H. Chludil, A.M. Seldes, C.A. Pujol,
E.B. Damonte. Two new cytotoxic and virucidal trisulfated triterpene glycosides from
the Antartic sea cucumber Staurocucumis liouvillei. Journal of Natural Products 64: 732736, 2001.
25. M.E.R. Duarte, D.G. Noseda, M.D. Noseda, S. Tulio, C.A. Pujol, E.B. Damonte.
Inhibitory effect of sulfated galactans from the marine alga Bostrychia montagnei on
herpes simplex virus replication in vitro. Phytomedicine 8: 53-58, 2001.
26. N. López, L. Scolaro, C. Rossi, R. Jácamo, N. Candurra, C. Pujol, E.B. Damonte,
M.T. Franze-Fernández. Homologous and heterologous glycoproteins induce protection
against Junin virus challenge in guinea pigs. Journal of General Virology 81: 1273-1281,
2000.
27. C.C. García, N.A. Candurra, E.B. Damonte. Antiviral and virucidal activities against
arenaviruses of Zinc-finger active compounds. Antiviral Chemistry and Chemotherapy
11: 231-238, 2000.
28. P.J. Cáceres, M.J. Carlucci, E.B. Damonte, B. Matsuhiro, E.A. Zúñiga. Carrageenans
from Chilean samples of Stenogramme interrupta (Phyllophoraceae): structural analysis
and biological activity. Phytochemistry 53: 81-86, 2000.
Trabajos de actualización en publicaciones periódicas y/o libros
1. E.B. Damonte, C.C. García. Perspectives for the therapy against arenavirus infections.
En: Antiviral Drug Discovery for Emerging Diseases and Bioterrorism Threats, P.F.
Torrence (Ed), J. Wiley & Sons, New York, p. 115-138, 2005.
2. E.B. Damonte, C.A. Pujol, C.E. Coto. Prospects for the therapy and prevention of
dengue virus infections. Advances in Virus Research 63: 239-285, 2004.
3. E.B. Damonte, M.C. Matulewicz, A.S. Cerezo. Seaweed sulfated polysaccharides as
antivirals. Current Medicinal Chemistry 11: 2399-2419, 2004.
4. E.B. Damonte, C.E. Coto. Treatment of arenavirus infections: from basic studies to
the challenge of antiviral therapy. Advances in Virus Research 58: 125-155, 2002.
5. E.B. Damonte. Junin virus. En: Encyclopedia of Molecular Medicine, T.E. Creighton
(Ed), J. Wiley & Sons, New York, p.1844-1846, 2002.
6. M.C. Matulewicz, E.B. Damonte, A.S. Cerezo. Estructura y actividad antiviral de
polisacáridos sulfatados de algas. Naturalia patagónica 1: 1-21, 2002.
Laboratorio Toxicología y Química Legal: Bioindicadores de estrés ambiental
antropogénico (Eva Kesten)
Publicaciones
1. Oneto M. L., Basack S.B., Casabé N.B., Fuchs J.S., Kesten E.M. (2005) “Biological
responses in the freshwater bivalve Corbicula fluminea and the earthworm Eisenia fetida
exposed to fenitrothion”; Fresenius Environmental Bulletin, , vol. 14, Nº 8, 716-720.
2. Fuchs J., Casabé N., Oneto M.L., Di Lello A., Lami M., Bongiovanni D., Vaccarezza
M., Gómez Segura O., Vázquez C., Sánchez-Rivas C., Kesten EM (2003). “Ensayos de
biorremediación de un suelo contaminado con trinitrotolueno (TNT)”. En “Toxicología y
Química Ambiental. Contribuciones para un desarrollo sustentable”, SETAC Press,
Buenos Aires, Argentina, 244-246.
3. Prieto González E.A., Fuchs J., Casabé N., Oneto M.L., Kesten E. (2003) “Ensayo
cometa en celomocitos de lombrices (Eisenia fetida) expuestas a 2,4,6-trinitrotolueno
(TNT)”. En “Toxicología y Química Ambiental. Contribuciones para un desarrollo
sustentable”, SETAC Press, Buenos Aires, Argentina, 164-166.
4. Casabé N.B., Oneto M.L., Fuchs J.S., Sánchez-Rivas C., Kesten E.M. (2003)
"Nitrocompuestos aromáticos explosivos: biotransformación, toxicidad y
remediación". Acta Bioquím. Clín. Latinoam. 37, 47-58.
5. Gürtler, R.E; Oneto, M.L.; Cecere; M.C; Castañera, M.B., Canale, D.M. (2001) “A
simple method to identify triatomine feces in sensing devices used in vector surveillance
programs” J. Med. Entomol., 38 (2), 147-152.
6. Fuchs J.S., Oneto M.L., Casabé N.B., Gómez Segura O., Tarulla R., Vaccarezza M.,
Sánchez-Rivas C., Kesten E.M., Wood E.J. (2001) “Ecotoxicological Characterization of
a Disposal Lagoon from a Munition Plant”. Bull. Environ. Contam. Toxicol. 67, 696-703.
Laboratorio de Inmunoquímica: Inmunología de mucosas (Ernesto Massouh)
Publicaciones
1. “Expression of IL-15, IL-18 and NOS.II in contralateral eyes of BALB/c mice during
the development of HSV-induced keratitis.
Cavalieri, H.;Gamba,G.;Courreges,M.;Massouh,E.;Benencia,F.
Immunology Letters,96:295-298,2005
2. “ Nitric oxide modulation of the immune response against cholera toxin-adjuvanted
ovalbumin administered by the intranasal route”
Gamba.G.;Bonorino,P.;Gonzalez,R.;Benedetti,R.;Cavalieri,H.;Courreges,M.;Masouh,E.;
Benencia,F.
Immunology Letters,92:245-252,2004.
3. “Early inhibition of nitric oxide production increase HSV-1 intranasal infection “
Gamba,G.;Cavalieri,H.;Courreges, M.;Massouh,E.;Benencia,F.
J. Med. Virol.,73:313-322,2004.
4. ”Nitric oxide and herpes simplex virus vaginal infection in Balb/c mice”.
Benencia, F.;Gamba, G.;Cavalieri,H.;Courreges,M.;Benedetti,R.;Villamil,M.;Massouh,E.
Virology, 309:75-84,2003.
5. ”Effect of undernourishement on HSV-1 ocular infection in the rat model”.
Benencia,F;Courreges,M.;Benedetti,R.;Gamba,G.;Cavalieri,H.;Massouh,E.
International Journal of Experimental Pathology, 83:57-66,2002.
6. “Intranasal infection with HSV-1 in undernurrished rats”
Benencia, F.;Gamba,G.; Courreges, M.; Benedetti,R.; Massouh,E.
Nutrition Research ,21:1435-1446,2001.
7. ”Effect of Aminoguanidine, a nitric oxide synthase inhibitor, on ocular infection with
Herpes Simplex virus in Balb/c mice”
Benencia, F.;Gamba, G.; Courreges, M. ;Massouh ,E.
Investigative Ophthalmology and Visual Science,42:6,1277-84,2001.
Laboratorio de Genética y Ecología Microbianas (Beatriz Méndez)
Publicaciones
1. Pablo I. Nikel, M. Julia Pettinari, Beatriz S. Méndez, Miguel A. Galvagno. Statistical
optimization of a culture medium for biomass and poly(3-hydroxybutyrate) production by
a recombinant Escherichia coli strain using agroindustrial by-products. International
Microbiology 8: 243-250. 2005
2. Nicolás D. Ayub, M.Julia Pettinari, Jimena A. Ruiz and Nancy I. López. A
polyhydroxybutyrate- producing Pseudomonas sp. Isolated from Antactic environments
with high stress resistance. Current Microbiology 49: 170-174. Springer Verlag New
York 2004
3. Ruiz, J.A., López, N.I,Pettinari, M.J. and Méndez, B.S. Role of polyhydroxyalkanoates
(PHAs) in bacterial stress resistance. Proceedings of the International Symposium on
Biotechnology. San Miguel de Tucumán, 2004.
4. Ruiz,J.A., López, N.I. and Mendez, B.S. rpoS gene expression in carbon-starved
cultures of the polyhydroxyalkanoate accumulating species Pseudomonas
oleovorans. Current Microbiology. 48: 396-400. 2004.
5. López, NI, Austin, A., Sala, O. and Méndez, B.S. Controls on nitrification in a
water-limited ecosystem: experimental inhibition of ammonia-oxidising bacteria in the
patagonian steppe. Soil Biol. Biochem.35: 1609-1613. 2003
6. Costa, C.S., Pettinari, M.J., Méndez, B.S. and Antón, D.N. Null mutations in the
essential gene yrfF (mucM) are not lethal in rcsB, yojN or rcsC strains of Salmonella
enterica serovar Typhimurium.FEMS Microbiol Lett. 222:25-32.2003
7. Vazquez, G.J., Pettinari, M.J. and Méndez, B.S. Evidence of an association between
Poly (3-hydroxybutyrate) accumulation and phosphotransbutyrylase expression in
Bacillus megaterium. Int. Microbiol. 6: 127-129. 2003.
8. Pettinari, M.J.,Chanetón,L.,Vazquez,G.J., Steinbüchel,A. and Méndez,B.S.Insertion
sequence - like elements associated with putative polyhydroxybutyrate regulatory genes
in Azotobacter sp. FA8. Plasmid 50: 36-44. 2003
9. Pettinari, M. J., Vazquez, G. J ., Silberschmidt,D., Rehm B., Steinbüchel A. and
Méndez,B.S. Poly(3-hydroxybutyrate) genes in Azotobacter sp. FA8.Appl.
Environ.Microbiol. 67: 5331-5337. 2001
10. Giacomodonato, M.N., Pettinari, M.J., Souto, G., Méndez, B.S. and López, N.I. A
PCR – based method for the screening of bacterial strains with antifungal activity in
suppressive soybean rhizosphere. World J. Microbiol. Biotechnol.17: 51-55. 2001
11. Ruiz,J.A., López N.I., Fernández, R. and Méndez B.S Polyhydroxyalkanoate
degradation is associated with nucleotide accumulation and enhaces stress resistance and
survival of Pseudomonas oleovorans in natural water microcosms. Appl. Environ.
Microbiol 67: 225-230. 2001
12. Vazquez, G.J., Pettinari, M.J. and Méndez, B. S Phosphotransbutyrylase expression
in Bacillus megaterium. Curr. Microbiol. 42: 345- 349. 2001
Publicaciones electrónicas
1. Pseudomonas oleovorans rpoS gene for RNA polymerase sigma factor.
ACCESSION AJ519340. 2002
2. Azotobacter sp. FA8 phaF gene, phaP gene, phaR gene, ORFB and ORFA. EMBL
nucleotide accession number AJ496234. 2002 ( incluida en la publicación 8)
3. Azotobacter sp. FA8 phbA gene for beta-ketothiolase and phbC gene for PHB synthase
EMBL nucleotide accession number AJ319748.2001( incluida en la publicación 9)
4. Azotobacter sp. FA8 phaB gene for acetoacetyl-CoA reductaseEMBL nucleotide
accession number AJ311166 .2001.( incluida en la publicación 9)
5. Bacillus megaterium ptb gene for phosphotransbutyrylase. EMBL nucleotide accession
number AJ278958. 2000 (Incluida en la publicación12)
6. EMBL nucleotideaccession number: AJ277459. Unidentified ammonia oxidizing
bacterium UBA6-1 partial amoA gene for ammonia monooxigenase. 2000
1. Méndez, B. S. ...las cosas por su nombre. Tarea harto difícil si de bacterias se trata.
Boletín de la Asociación Argentina de Microbiología. 2003
2. Stoppani, A., Méndez, B. S. and Sordelli, D. Remembering a Microbiologist: Alfredo
Sordelli. Enviado a publicación a International Microbiology. 4: 237-238. 2001.
Laboratorio de Biología Molecular: Transducción de señales (Silvia Moreno)
Publicaciones
1. Mucor rouxii ultrastructure: cAMP and actin cytoskeleton.
Pereyra,E., Ingerfeld, M., Anderson, N., Jackson, S.L., Moreno, S.
Protoplasma, en prensa, 2005.
2. Cell-growth dependent subcellular localization of p8.
Valacco, P., Varone, C. Malicet, C., Cánepa, E., Iovanna, J.L., Moreno, S.
J. Cell. Biochem., en prensa, 2005.
3. Glucose dependent activation and phosphorylation of protein kinase A in
Saccharomyces cerevisiae.
Portela, P., Moreno, S.
Cellular Signal., en prensa, 2005.
4. Combined strategy using pure enzymes and whole cells as biocatalysts in the
preparation of 2-hydroxyesters and gamma-butyrolactones from 2-oxoglutaric acid.
Rustoy, E.M., Pereyra, E., Moreno, S. and Baldessari, A.
Tetrahedron Asymmetry, 15: 3763-.3768, 2004.
5. Protein kinase A is involved in the control of morphology and branching during
aerobic growth in Mucor circinelloides.
Lübbehüsen, T.*, González Polo, V.* (equal contribution), Rossi, S. Nielsen, J., Moreno,
S., McIntyre, M. and Arnau, J.
Microbiology (UK), 150: 143-150,2004.
6. RGD-containing peptides and cAMP have antagonistic roles in the morphology of
Mucor rouxii.
Pereyra, E., Argimón, S., Jackson, SL and Moreno, S.
Protoplasma. 222: 23-30, 2003.
7. Activation state of Protein Kinase A as measured in permeabilised Saccharomyces
cerevisiae cells correlates with PKA-controlled phenotypes in vivo.
Portela, P.,Van Dijck, P., Thevelein, J. and Moreno, S.
FEMS Yeast Research, 3: 119-126, 2003.
8. In vivo and in vitro phosphorylation of two isoforms of yeast pyruvate kinase by
protein kinase A.
Portela, P., Howell, S., Moreno, S. and Rossi, S.
J.Biol.Chem., 277: 30477-30487, 2002.
9. The HMG-I/Y-related protein p8 binds to p300 and Pax2 trans-activation-domain
interacting protein to regulate the trans-activation activity of the Pax2A and Pax2B
transcription factors on the glucagon gene promoter .
Hoffmeister, A., Ropolo, A., Vasseur, S., Mallo, G.V., Bodeker, H., Ritz-Laser, B.,
Dressler, G.R., Vaccaro, M.I., Dagorn, J.C., Moreno, S. and Iovanna, J.L.
J.Biol.Chem. 277: 22314-22319, 2002.
10. Chemo- and stereoselective reduction of beta-keto esters by spores and various
morphological forms of Mucor rouxii.
Mangone, C., Pereyra, E. , Argimon, S., Moreno, S. and Baldessari, A.
Enzyme Microbial Technol. 30: 596-601, 2002.
11. Protein kinase A activity in permeabilized cells as an approximation to in vivo
activity.
Sorol, M.R., Pereyra, E., Mizyrycki, C., Rossi, S. and Moreno, S.
Exp.Cell Res. 271: 337-342, 2001.
12. TGFb-1 enhances the Smad transcriptional activity through activation of p8
gene expression.
García-Montero,AC, Vasseur,S., Giono, L., Cánepa, E., Moreno, S., Dagorn, JL and
Iovanna, JL.
Biochem. J. 357: 249-253, 2001.
13. Overexpression of regulatory subunit of protein kinase A in Saccharomyces
cerevisiae: genetic and biochemical considerations.
Portela, P.*, Zaremberg, V.* and Moreno, S. (* equal contribution)
Microbiology, 147, 1149-1159, 2001.
14. Structural studies of human p8, a HMG-like protein , with DNA binding activity
enhanced by phosphorylation. Encinar, J., Mallo, GV, Mizyrycki, C., Giono, L.,
González-Ros, JM, Rico, M, Cánepa, E., Moreno, S., Neira, JL and Iovanna, JL.
J.Biol.Chem, 276: 2742-2751, 2001.
15. Structural and functional analysis of the cAMP binding domain from the regulatory
subunit of Mucor rouxii protein kinase A.
Sorol, M.R., Pastori, R., Muro,A., Moreno, S. and Rossi,S.
Arch.Biochem. Biophys., 382: 173-181, 2000
16. The mechanism of activation of cAMP-dependent protein kinase. In Mucor rouxii the
apparent specific activity of the cAMP activated holoenzyme is different to that of its free
catalytic subunit.
Zaremberg V., Donnella-Deana A., and Moreno S.
Arch.Biochem.Biophys., 381: 74-82, 2000.
17. Threshold level of protein kinase A activity and polarized growth in Mucor rouxii.
Pereyra, E., Mizyrycki, C. and Moreno,S.
Microbiology, 146: 1949-1958, 2000.
1. Biochemistry and molecular biology of the stress-associated protein p8
J.L.Iovanna, S.Vasseur, and S.Moreno
Recent Res.Devel.Biochem. 3 (2002): 393-407.
Research Signpost , Kerala, India.
Laboratorio de Análisis Biológicos (Alcira Nesse)
Publicaciones
1. "Homeostasis del hierro. Mecanismos de absorción, captación celular y regulación".
Actualización. Pérez, G; Vittori, D; Pregi, N; Garbossa, G; Nesse, A. Acta Bioquím Clín
Latinoamer, ISSN 0325-2957, Vol. 39, N°3, 2005. En prensa.
2. "Aluminum exposure affects transferrin-dependent and -independent iron uptake by
K562 cells". Pérez G, Pregi N, Vittori D, Di Risio C, Garbossa G, Nesse A. Biochim
Biophys Acta Elsevier, ISSN 0005-2736, 1745:124-130, 2005.
3. "The distinct erythropoietin functions that promote cell survival and proliferation are
affected by aluminum exposure through mechanisms involving erythropoietin receptor".
Vittori D, Pregi N, Pérez G, Garbossa G, Nesse A. Biochim Biophys Acta, Elsevier,
ISSN 0005-2736, 1743:29-36, 2005.
4. "Aluminio: culpable o inocente?". Nesse A, Garbossa G, Pérez G. Vittori D, Pregi N.
Química Viva Año 1, número 2, 2003. Revista electrónica con referato nacional, del
Depto. de Química Biológica, FCEN, UBA (www.quimicaviva.fcen.uba.ar). ISSN 16667948.
5. "Tamm-Horsfall protein excretion to predict the onset of renal insufficiency". Romero
MC, Zanaro N, González L, Trigo P, Imventarza O, Nesse A. Clin Biochem, Elsevier,
ISSN 0009-9120, 35:65-68, 2002.
6. "Human erythroid cells are affected by aluminium. Alteration of membrane band 3
protein". Vittori D, Garbossa G, Lafourcade C, Pérez G, Nesse A. Biochim Biophys
Acta, Elsevier, ISSN 0005-2736, 1558:142-150, 2002.
7. "Toxicidad del aluminio sobre el sistema eritropoyético. Mecanismos involucrados".
Actualización. Pérez G, Vittori D, Garbossa G, Nesse A. Acta Bioquím Clín Latinoamer,
ISSN 0325-2957, 36:41-50, 2002.
8. "Disturbance of cellular iron uptake and utilisation by aluminium". Pérez G, Garbossa
G, Di Risio C, Vittori D, Nesse A. J Inorg Biochem, Elsevier, ISSN 0162-0134, 87:2127, 2001.
9. "Dissimilar behavior of lymph cells in response to the action of aluminum. In vitro and
in vivo studies". Lauricella AM, Garbossa G, Nesse A. Int Immunopharmacol, Elsevier,
ISSN 1567-5769, 1:1725-1732, 2001.
10. "Lipoproteínas de baja densidad modificadas en pacientes con insuficiencia renal.
Detección por electroforesis". Lauricella AM, Elbert A, Beresán H, Nesse A. Nefrol
Latinoamer, Sociedad Latinoamericana de Nefrología, 7:27-34, 2000.
1. Aluminium toxicity in erythropoiesis. Mechanisms related to cellular dysfunction in
Alzheimer's Disease. Nesse A, Garbossa G. En Aluminium and Alzheimer's Disease. The
Science that describes the Link. C Exley (ed.), Elsevier, Amsterdam, cap. 13, pp.261-278,
2001. ISBN 0 444 50811 2.
1. "La otra cara del aluminio". Entrevista, realizada por Cecilia Draghi, al grupo de
investigación dirigido por la Dra. Alcira Nesse: Revista "Exactamente" de la Facultad de
Ciencias Exactas y Naturales, Universidad de Buenos Aires, ISSN 1514-920X, vol. 10
(27):30-33, 2003.
Laboratorio Expresión Génica en Mama y Apoptosis (Adalí Pecci)
Publicaciones
1. "6,19-Sulfur-bridged Progesterone analogues with antiimmunosuppressive activity".
A.S. Veleiro, A. Pecci, M.C. Monteserín, R. Baggio, M.T. Garland, C.P. Lantos and G.
Burton. J. of Medicinal Chemistry (2005). 48:5675-83.
2. “Progestins Induce Transcriptional Activation of Signal Transducer and Activator of
Transcription 3 (Stat3) Via Jak and Src-Dependent Mechanism in Breast Cancer Cells”.
C. Proietti, M. Salatino, C. Rosemblit, R. Carnevale, A. Pecci, A.R. Kornblihtt, A.A.
Molinolo, I. Frahm, E.H. Charreau, R. Schillaci and P. V. Elizalde. Mol. Cell. Biol.
(2005). 25:4826-40.
3. "The GnRH antagonist Antide inhibits apoptosis of preovulatory follicle cells in rat
ovary". F. Parborell, G. Irusta, A. Vitale, O. Gonzalez, A. Pecci y M. Tesone. Biol.
Reprod., (2005). 72:659-66.
4. "Steroid hormones induce bcl-X gene expression through direct activation of distal
promoter P4". L. Rocha Viegas, G.P. Vicent, J.L. Barañao, M. Beato and A. Pecci. J.
Biol. Chem. (2004) 279:9831-9.
5. "Involvement of Bax protein in the prevention of glucocorticoid-induced thymocytes
apoptosis by melatonin". E. Hoijman, L. Rocha Viegas, M.I. Keller Sarmiento, R.E.
Rosenstein and A. Pecci. Endocrinology. (2004) 145:418-25.
6. “Heregulin induces transcriptional activation of the progesterone receptor by a
mechanism that requires a functional ErbB-2 and MAPK activation in breast cancer
cells”. L. Labriola, M. Salatino, A. Pecci, O.A. Coso, A.R. Kornblihtt, C. Proietti, E.H.
Charreau and P.V. Elizalde. Mol. Cell Biol. (2003). 23:1095-1111.
7. ”Differences in nuclear binding characteristics of agonist-activated glucocorticoid
receptor would determine specific responses”. G.P. Vicent,, A. Pecci, A. Ghini, G.
Piwien-Pilipuk and M. D. Galigniana. Exp. Cell Res. (2002). 276:142-154.
8. “Effect of a gonadotropin-releasing hormone agonist on rat ovarian follicle apoptosis:
Regulation by EGF and the expression of bcl-2-related genes”. F. Parborell, A. Pecci, O.
Gonzalez, A. Vitale and M. Tesone. Biol. Reprod., (2002). 67:481-486.
9. “Promoter choice influences alternative splicing and determines the balance of
isoforms expressed from the mouse bcl-x gene”. Pecci A., L. Rocha Viegas, J.L. Barañao
and M. Beato. J. Biol. Chem. (2001). 276:21062-9.
1. “Mecanismos de acción celular de los glucocorticoides y de los
mineralocorticoides”.A. Sánchez-Pacheco, A. Pecci y G.P. Vicent. En “Actualizaciones
en Endocrinología”, Mon. No. 6: “Glándulas Suprarrenales”. Cap. 2:35-46, R. Yturriaga
Matarranz; C. Pavía Sesma y C. Dieguez. Ed. Mc. Graw-Hill/Interamericana. Madrid,
España. (2000).
Laboratorio de Inmunofarmacología (Claudia Pérez Leirós)
Publicaciones
1. Rosignoli F, Roca V., Meiss R., Receta J., Gomariz R.P., Pérez Leirós C. (2005). A
defective signalling in salivary glands precedes the autoimmune response in the NOD
mouse model of sialadenitis. Clin Exp Immunol (en prensa).
2. Roca V, Rosignoli F, Calafat M, Pérez Leirós C (2004). Lack of nitric oxide-mediated
regulation of amylase secretion stimulated by VIP in parotid glands of NOD mice. Int.
Immunopharmacol 4/14:1837-1844.
3. Rosigmoli F, Roca V, Meiss R, Pregi N, Pérez Leirós C. (2004). Inhibition of
calcium-calmodulin kinase restores nitric oxide production and signaling in
submandibular glands of a mouse model of salivary dysfunction. Br J Pharmacol 143:
1058-1065
4. Rosignoli F, Pérez Leirós C. (2002). Nitric oxide synthase I and VIP-activated
signaling are affected in salivary glands of NOD mice. J Neuroimmunol 130: 109-116.
5. Rosignoli F, Pérez Leirós C. (2002). Activation of nitric oxide synthase through
muscarinic receptors in rat parotid gland. Eur J Pharmacol 439:27-33.
6. Rosignoli F, Goren N, Pérez Leirós C. (2001). Alterations in the activity and
expression of NOS in submandibular glands of NOD mice. Clin Immunol 101: 86-93.
7. Pérez Leirós C, Rosignoli F, Genaro A, Sales ME, Sterin Borda L, Borda E. (2000)
Differential activation of nitric oxide synthase through muscarinic acetylcholine receptors
in rat salivary glands. J Aut Nerv Sys 79: 99-107.
Laboratorio de Enzimología, Estrés oxidativo y Metabolismo (María del Carmen
Ríos)
Publicaciones
1. Chemicals that modulate vesicular stomatitis virus (-VSV-) infection in Vero cells.
Riva D, Ríos de Molina MC, Rocchetta I, Coulombié FC, Mersich SE. (aceptado para su
publicación en Intervirology)
2. Chromium toxicity to Euglena gracilis strains depending on the physicochemical
properties of the culture medium. Rocchetta I, Ruiz L, Ríos de Molina MC, Conforti V.
(aceptado para su publicación en Bulletin of Environmental Contamination and
Toxicology)
3. Effect of chromium on the fatty acid composition of two strains of Euglena gracilis.
Rocchetta I, Mazzuca M, Conforti V, Ruiz LB, Balzaretti V, Ríos de Molina MC.
Environmental Pollution, 2005, Oct.3 (epud ahead of print).
4. Abnormal kinetic behavior of Uroporphyrinogen decarboxylase obtained from rats
with hexachlorobenzene-induced porphyria. Chaufan G, Corvi M, San Martín de Viale
MC, Cárdenas ML, Ríos de Molina MC. J. Biochem. Mol. Toxicol. 19, 2005: 19-24.
5. Antioxidants and methimazole in the treatment of Graves disease: Effect on seric and
urinary malondialdehyde levels. Guerra L, Ríos de Molina MC, Miler A, Moiguer S,
Karner M, Burdman J. Clin Chim Acta, 352, 2005:115-120.
6. Niveles de TBARS plasmáticas y urinarios en pacientes hipertiroideos, pretratamiento
y postratamiento con antioxidantes. Guerra L, Moiguer S, Karner M, Sreder C, Burdman
J, Ríos de Molina MC. Rev Cub Invest Bioméd 23(2) 2004: 105-8.
7. Effects of sublethal concentrations of copper on three strains of green microalgae
under autotrophic and mixotrophic culture conditions. Schiariti A., Juárez A., Rodriguez
MC. Archiv fur Hydrobiologie, Algological Studies 114 (2004): 143-147.
8. Estudio del estrés oxidativo en 2 cepas de Euglena Gracilis. Rocchetta I., Ruiz L.,
Conforti V., Ríos de Molina M. C. Rev Cub Invest Biomédicas, 22(2) (2003) 105-108.
9. El estrés oxidativo y el destino celular. Ríos de Molina M.C. Química Viva, 2 (1)
(2003). Revista electrónica.
10. Estrés oxidativo inducido por cobre en cultivos de microalgas verdes. Schiariti A.,
Juárez A., Rodriguez MC. En: J. Herkovitz (ed.) Toxicologia y Quimica Ambiental.
Contribuciones para un desarrollo sustentable. SETAC LA, Instituto de Cs. Ambientales
y Salud, Fundación PROSAMA, 2003: 156-158.
11. The decrease in uroporphyrinogen decarboxylase activity induced by ethanol
predisposes rats to the development of porphyria and accelerates xenobiotic-triggered
porphyria, regardles of hepatic damage. Ríos de Molina M. C., Mazzetti M.B.,
Galigniana M., Aldonatti C., Tomio J.M. y San Martín de Viale L. C. Braz. J. Med. Biol.
Res. 35(11) (2002) 1273-1283.
12. Comparison between crab hepatopancreas and rat liver uroporphyrinogen
decarboxylase. Chaufan G., Corvi M., Armesto A., San Martín de Viale L. C., Luquet C.,
Ríos de Molina M. C. Comparative Biochemistry and Physiology, Part B. 133/2 (2002)
251-256.
13. Antioxidants in the treatment of Graves disease. Guerra L. N., Moiguer S., Karner
M., Ríos de Molina M. C., Sreider C. M. and Burdman J. A. IUBMB Life 52 (2001) 1-5.
14. How does hexachlorobenzene affect Uroporphyrinogen decarboxylase? Chaufan G.,
Ríos de Molina M. C. y San Martín de Viale L. C. Int. J. Biochem. Cell. Biol. 33 (2001)
621-630.
15. Co-cultivo de Micobacterias y Cyanobacterium Minervae (COP.) Komárek and
Anagnostidis (Cianoprokariota). Squadrone M. J., Wenzel M. T., Ríos de Molina M. C.
Dominguezia 16(1) (2000) 5-14.
Laboratorio de Estudios de estrés osmótico en bacterias Gram positivas (Carmen
Sánchez)
Publicaciones
1. López CS, Alice A., Heras H. Rivas EA. & Sanchez-Rivas C. (2005) “Role of the
anionic phospholipids in the adaptation of Bacillus subtilis to high salinity.”
Microbiology en revision
2. Prado Acosta M, Valdman E., Battaglini F., Leite S.G.F. and Ruzal S. (2005)
”Biosorption of copper by Paenibacillus polymyxa cells and their exopolysaccharide
World Journal of Microbiology and Biotechnology 21 en prensa ISSN: 0959-3993
3. Piuri M., Sanchez-Rivas C., Ruzal S.M. (2005) Cell wall modifications during osmotic
stress in Lactobacillus casei Journal of Applied Microbiology 98(1):84-95 (ISI Impact
factor JCR2003: 1.743) Blackwell Publishing ISSN 1365-2672
4. Alice AF, G. Pérez-Martinez & C. Sanchez-Rivas (2003) “Phosphoenolpyruvate
phosphotransferase system and N-acetyl glucosamine metabolism in Bacillus
sphaericus.” Microbiology; 149: 1687-1698
5. Casabé Norma, María Luisa Oneto, Julio Fuchs, Carmen Sánchez-Rivas y Eva Kesten
(2003). “ Nitrocompuestos aromáticos explosivos: biotransformación, toxicidad y
remediación Acta Bioquímica clínica LatinoAmericana. Vol XXXVII- nº1
6. Piuri M., C. Sanchez-Rivas and S.M. Ruzal. (2003) Adaptation to high salt in
Lactobacillus: Role of peptides and proteolytic enzymes Journal of Applied
Microbiology 95(2)372-379 (ISI Impact factor JCR2003: 1.743) Blackwell Publishing
ISSN 1365-2672
7. Ruzal S.M. and Sanchez-Rivas C. (2003) Effect of Glutamate Synthase (Gogat) Activity
In Bacillus subtilis Spore Properties.” Current Microbiology 47(3):208-13 (ISI Impact
factor JCR2002: 1.21) Springer-Verlag ISSN 0343-8651
8. Alice A., G Perez Martinez & C Sánchez de Rivas (2002). “Existence of a true
Phosphofructokinase in Bacillus sphaericus: cloning and sequencing of the pfk gene”.
Applied and Environmental Microbiology vol 68 (12) 6410-6415
9. S. Fuchs, M.L. Oneto, N.B. Casabé, O. Gómez Segura, R. Tarulla, M. Vaccarezza, C.
Sánchez-Rivas, E.M. Kesten and E.J Wood (2001) - "Ecotoxicological Characterization
of a Disposal Lagoon from a Munition Plant” Bulletin of Environmental Contamination
and Toxicology. Vol. 67, 696-703
10. Priano G., Ruzal SM and F. Battaglini
(2001) “Evaluation of an
electrochemiluminescent method for the detection of microorganism resistance to ßlactam antibiotics. Analytical Biochemistry 290(2):379-82 (ISI Impact factor JCR2002:
2.37) Elsevier ISSN 0003-2697
11. Lopez C.S., Heras H., Garda H., Ruzal S., Sanchez-Rivas C. and Rivas E. (2000).
“Biochemichal and biophysical studies of Bacillus subtilis envelopes under hyperosmotic
stress”. Internatinal Journal of Food Microbiology, 55: 137-142 (ISI Impact factor
JCR2003: 2.26) Elsevier ISSN: 0168-1605
12. Cortón E, M. Piuri, F. Battaglini and S.M. Ruzal (2000) “Characterization of
Lactobacillus Carbohydrate Fermentation Activity using Immobilised Cell Technique”
Biotechnology Progress, 16(1): 59-63 (ISI Impact factor JCR2001: 1.821) American
Chemical Society ISSN 8756-7938
1. En « Toxicología y Química ambiental : Contribuciones para un desarrollo
sustentable » de SETAC LA Editor: J. Hercovits. 2003 pp.244-246
“Ensayos de biorremediación de un suelo contaminado con trinitrotolueno (TNT).”
Fuchs, J., Casabé N., Oneto M.L., Di Lello A., Lami M., Bongiovanni D., Vaccarezza
M., Gómez Segura O., Vázquez C., Sánchez-Rivas C. y Kesten E.
Laboratorio de Metabolismo del hemo: Porfirias y enfermedades relacionadas
(Victoria Parera y María Victoria Rossetti)
Publicaciones
1. Design of a novel dendritic derivative of aminolevulinic acid to improve the outcome
of photodynamic therapy” Di Venosa G, Casas A., Battah S, Dobbin P, Fukuda H,
MacRobert A, Batlle A. Int. J. Biochem. Cell Biol., 38: 82-91 (2006).
2. The role of inherited and acquired factors in the development of Porphyria Cutanea Tarda
in the Argentinean population. M Mendez, MV Rossetti, AM. del C Batlle , VE Parera.
Journal of the American Academy of Dermatology. 52 (3) 417-424 (2005)
3. A spectrophotometric method for estimating hemin in biological systems. Lombardo
M.E., Araujo L.S., Ciccarelli A.B. & Batlle A. Anal. Biochem. (2005) 341: 199-203
4. Sensitivity to ALA-PDT of cell lines with different nitric oxide production and resistance
to nitric oxide cytotoxicity”. Di Venosa,G.; Perotti,C.; Fukuda,H.; Batlle,A. & Casas, A. J.
Photochem. Photobiol. B, 80: 195-202(2005).
5. Aminolevulinic acid: from its unique biological function to its star role in photodynamic
therapy. Fukuda H, Casas A & Batlle A” Int. J. Biochem. Cell Biol, 37: 272-276 (2005).
6. No cross resistance between ALA-PDT and Nitric Oxide” Di Venosa G, Casas A, Fukuda
H, Perotti C & Batlle A. Nitric Oxide Biol. Chem,13: 155-162 (2005).
7. Glutathione depletion and anaesthesia in mice alter heme and drug metabolising enzymes.
Buzaleh, A.M. & Batlle, A. Biochim. Biophys. Acta 1723 (2005) 128-134
8. Efecto de la administración de los anestésicos Enflurano e Isoflurano a ratones con
niveles inducidos y deprimidos de Citocromo P450. Estudios sobre el sistema enzimático
metabolizante de drogas. Martínez, M. del C.; Buzaleh, A.M. & Batlle, A. Acta Bioquím.
Clin. Latinoam. 39 (2005) 37-42
9. Effects of repeated administration with CP-55,940, a cannabinoid CB1 receptor agonist
on the metabolism of the hepatic heme. A. Fontanellas, A.; Manzanares, J.; García-Bravo,
M., Buzaleh, A.M.; Méndez, M.; Oliva, J.M.; Batlle, A. ; Palomo, T. & Enriquez de
Salamanca, R. Int. J. Biochem. Cell Biol. 37 (2005) 1620-1625
10. Heme oxytenase, aminolevulinate acid synthetase and the antioxidant system in the
brain of mice treated with porphyrinogenic drugs. Rodríguez, J.L.; Martínez, M. del C.;
Gerez, E.; Batlle, A. & Buzaleh, A.M. Cell. Mol. Biol. 51 (2005) 487-494
11. Volatile anaesthetics induce biochemical alterations in the heme pathway in a Blymphocyte cell line established from hepatoerythropoietic porphyric patients (LBHEP) and
in mice inoculated with LBHEP cells. Buzaleh, A.M; García Bravo, M.; Navarro, S.; Moran
Jimenez, M.J., Méndez, M.; Batlle, A.; Fontanellas, A. & Enríquez de Salamanca, R. Int. J.
Biochem. Cell Biol.36 (2004) 216-222
12. A method for separating ALA from ALA derivatives using ionic exchange
chromatography”. Di Venosa G, Fukuda H, Perotti C, Batlle A & Casas A. J.
Photochem. Photobiol B.,75:157-63 (2004).
13. Porphyrin synthesis from ALA derivatives for Photodynamic therapy. In vitro and in
vivo studies”. Perotti C, Fukuda H, Di Venosa G, MacRobert A, Batlle A & Casas A. Br
J. Cancer, 90: 1660-1665 (2004).
14. Acute Porphyrias in the Argentinean population: A Review. VE Parera, A De Siervi, L
Varela, MV Rossetti, AM. del C Batlle Cellular and Molecular BIology 49 (4) 493-500
(2003)
15. 5-Aminolevulinic acid synthesis in epimastigotes of Trypanosoma cruzi. Lombardo
M.E., Araujo L.S. & Batlle A. Int. J. Biochem. Cell Biol. (2003) 35: 1263-1271.
16. Dietary and sexual correlates of carotenoid pigment expression in dove plumage. Mahler
B., Araujo L.S. & Tubaro P.L. The Condor (2003) 105: 258-267.
17. Topical application of ALA and ALA hexyl ester on a subcutaneous mammary
adenocarcinoma: tissue distribution”. C. Perotti, A.Casas, H. Fukuda, P. Sacca & A. Batlle.
Br J. Cancer , 88: 432-437 (2003).
18. Estudios genéticos de las porfirias agudas en Argentina. Adriana De Siervi, Manuel
Méndez, Laura Varela, María Victoria Rossetti, Victoria Parera, Alcira. Acta Bioquímica
Clínica Latinoamericana XXXVI (5) 505-513 (2002).
19. 5-aminolevulinic acid cytotoxic effects on human hepatocarcinoma cell lines. Adriana
De Siervi, Laura Varela, María Victoria Rossetti, Alcira Batlle. BMC Cancer 6-12 (2002)
20. Saccharomyces cerevisiae 5-aminolaevulinate dehydratase (HEM2) gene, promoter
and partial cds. Laura Varela, Adriana De Siervi , María Victoria Rossetti, Alcira Batlle.
NCBI AF349727 (2002)
21. Photodynamic Therapy of activated and resting lymphocytes and its antioxidant
adaptive response”. A.Casas, C.Perotti, H. Fukuda & A. Batlle. Lasers Med. Sci. 17: 4250 (2002).
22. ALA and ALA hexyl ester in free and liposomal formulations for the
photosensitisation of tumour organ cultures.”A. Casas, C. Perotti, M. Saccoliti, P. Sacca,
H. Fukuda, & A. Batlle. Br J. Cancer, 86: 837-842 (2002).
23. Scavengers protection of cells against ALA-based Photodynamic Therapy induced
damage”. C. Perotti, H. Fukuda, A. Casas & A. Batlle. Lasers Med. Sci, 17: 229-229
(2002).
24. ALA and ALA hexyl ester induction of porphyrins after their systemic administration
to tumour bearing mice. C.Perotti, A. Casas, H. Fukuda, P.Sacca & A. Batlle. Br. J.
Cancer, 87: 790-795 (2002).
25. In vitro photosensitisation of a murine mammary adenocarcinoma with Verteporfin”.
A.Casas, G.Di Venosa, A.Batlle & H.Fukuda. Cell. Mol. Biol, 48: 931-937 (2002).
26. The effects of some porphyrinogenic drugs on the brain cholinergic system.
Rodríguez, J.L.; Buzaleh, A.M.; Fossati, M..; Azcurra, J. & Batlle, A.M. del C. Cell. Mol.
Biol. 48 (2002) 103-110
27. Diagnosis of latent acute intermittent porphyria by genetic analysis. De Siervi A,
Varela LS, Méndez M, Parera VE, Batlle AM del C, Rossetti MV. Ann. Clin. Biochem
38 149-152 (2001)
28. Photosensitisation and mechanism of cytotoxicity induced by the use of ALA
derivatives in photodynamic therapy. A. Casas, H. Fukuda, G. Di Venosa & A. Batlle.
Br J. Cancer 85: 279-284 (2001).
29. ALA and ALA hexyl ester-induced porphyrin synthesis in chemically induced skin
tumours: the role of different vehicles on improving photosensitisation. A. Casas, C.
Perotti, H. Fukuda, L. Rogers, A. Butler & A. Batlle. Br J. Cancer, 85: 1740-1800
(2001).
30. Two new mutations (H106P and L178V) in the protoporphyrinogen oxidase gene in
Argentinean patients with Variegate Porphyria. Adriana de Siervi, Victoria E Parera,
Alcira M Del C. Batlle, María V Rossetti. Human Mutation. Mutation and Polymorphism
Report 16 (6) 532 (2000)
31. Porfiria Variegata: signos cutáneos, agudos y bioquímicos. Primer estudio genético en
pacientes argentinos. Adriana de Siervi, Victoria E Parera, Laura Varela, Alcira M Del C.
Batlle, María V Rossetti. Rev Argent Dermatol 81 94-100 (2000)
32. Mutations in Familial Porphyria Cutanea Tarda: two novel and two previously
described for Hepatoerythropoietic Porphyria. Manuel Mendez, María Victoria Rossetti,
Adriana De Siervi , Alcira M. Del C. Batlle, Victoria Parera. Human Mutation, Mutation
in Brief 16 (3) 269-270 (2000)
33. A novel mutation (1320InsT) identified in two Argentine families with Variegate
Porphyria. Adriana de Siervi, Victoria E Parera, Laura S Varela, Alcira M del C Batlle,
María V Rossetti. Human Mutation. Mutation and Polymorphism Report 16 (1) 96 (2000)
34. Identification and Characterization of two novel mutations that produce Acute
Intermittent Porphyria: a 3-base deletion (841-843delGGA) and a missense
mutation (T35M). A De Siervi, DE Weiss Cádiz, VE Parera, A M del C Batlle,
Rossetti MV. Human Mutation, Mutation in Brief 16 (4) 373 (2000)
35. Administration of volatile anaesthetics to animals treated with cobalt as inductor of
heme oxygenase.Buzaleh, A.M & Batlle, A. Pharmacol. Rev. Commun. 11 (2000) 39-47
36. The relevance of P-450 levels on enflurane and isoflurane action action in mice. Studies
on heme pathway. Buzaleh, A.M & Batlle, A. Clin. Exp. Pharmacol. Physiol. 27 (2000)
796-800
Laboratorio de Disturbios metabólicos por xenobióticos en modelos experimentales
(Leonor San Martín de Viale)
Publicaciones
1. A.C Cochón, MB Mazzetti and LC San Martin de Viale. “How hexachlorobenzene
impacts biochemistry - Recent studies in several tissues”. Trends in Cell and Molecular
Biology vol. 1(In press), 2005.
2. Lelli, SM., San Martín de Viale, LC. and Mazzetti, MB. “Response of glucose
metabolism enzymes in an acute porphyria model. Role of reactive oxygen species”.
Toxicology 216: 48-58, 2005.
3. G. Chaufan, M. Corvi, L. San Martín de Viale, M. L. Cárdenas and M.C. Ríos de
Molina. "Abnormal kinetic behaviour of Uroporphyrinogen decarboxylase obtained from
rats with hexachlorobenzene induced porphyria". J. Biochem. Mol. Toxicol. 19: 19-24,
2005.
4. S. Billi , A. Faletti, F. Fuentes, L. San Martin de Viale and A. Cochón. “Hepatic
arachidonic acid metabolism is disrupted after hexachlorobenzene treatment”. Toxicol.
Appl. Pharmacol. 204: 187-195, 2005.
5. M.C. Taira, M.B. Mazzetti, S.M. Lelli y L.C. San Martín de Viale. “Glycogen
metabolism and glucose transport in experimental porphyria”. Toxicology 197: 164-174,
2004.
6. M.B. Mazzetti, M.C. Taira, S.M. Lelli E. Dascal.; J.C. Basabe and L.C. San Martín de
Viale. “Hexachlorobenzene impairs glucose metabolism in a rat model of porphyria cutanea
tarda: a mechanistic approach”. Archives of Toxicology 78: (1) 25-33, 2004.
7. E. B. C. Llambías, C. Aldonatti and L. C. San Martín de Viale. "Tryptophan metabolism
via serotonin in rats with hexachlorobenzene experimental porphyria". Biochem.
Pharmacol. 66:35-42, 2003.
8. G. Chaufan, M. Corvi, A. Armesto, L.C. San Martín de Viale, C Luquet and M. C. Ríos
de Molina. "Comparison between crab hepatopancreas and rat liver uroporphyrinogen
decarboxylase". Comp. Biochem. Physiol. B Biochem Mol Biol 133(2): 251-256, 2002.
9. M.C. Rios de Molina, M.B. Mazzetti, M. Galigniana, C. Aldonatti, M.J. Tomio and L.C.
San Martín de Viale. "The decrease in uroporphyrinogen decarboxylase activity induced by
ethanol predisposes rats to the development of porphyria and accelerates xenobiotictriggered porphyria, regardless of hepatic damage". Braz. J. Med. Biol. Res , 35 (11): 12731283, 2002.
10. A.C. Cochón, N. González and L.C. San Martín de Viale. "Effects of the
porphyrinogenic compounds hexachlorobenzene and 3,5-diethoxycarbonyl-1,4dihydrocollidine on polyamine metabolism". Toxicology 176: 209-219, 2002.
11. A.C. Cochón, L.C. San Martín de Viale and S.C. Billi de Catabbi. "Phospholipid
alterations elicited by hexachlorobenzene in rat brain are strain dependent and porphyria
independent". Comp. Biochem and Physiol. Part C130: 199-207, 2001.
12. G. Chaufan, M.C. Rios de Molina and L.C. San Martín de Viale. "How does
hexachlorobenzene treatment affect liver uroporphyrinogen decarboxylase". Int. J. Biochem.
Cell Biol.33: 621-630, 2001.
13. S. Billi de Catabbi, C. Aldonatti and L. C. San Martín de Viale. “Heme metabolism after
discontinued hexachlorobenzene administration in rats: possible irreversible changes and
biomarkers for hexachlorobenzene persistence”. Comparative Biochem and Physiol. Part
C,127:165-175, 2000.
14. S. Billi de Catabbi, P. Setton-Advruj. N. Sterin Speziale, L. C. San Martín de Viale and
A. C. Cochon. “Hexachlorobenzene induced alterations on neutral and acidic
sphingomyelinases and serine palmitoyltransferase activities. A time course study in two
strains of rats”. Toxicology 149:89-100, 2000.
15. M. C. Fernandez-Tomé, S. Billi de Catabbi, C. Aldonatti, L. C.San Martín de Viale and
N. Sterin Speziale. “Heme metabolism and lipid peroxidation in rat kidney
hexachlorobenzene (HCB) induced porphyria. A compartmentalized study of biochemical
pathogenic mechanisms”. Kidney and Blood Pressure Research 23:20-26, 2000.
Laboratorio de Metabolismo del hemo en condiciones normales y patológicas
(Horacio Sancovich)
Publicaciones
1. "Disturbances on delta aminolevulinate dehydratase (ALA-D) enzyme activity by Pb 2+,
Cd2+, Cu2+; Mg2+, Zn2+, Na+, K+ and Li+: analysis based on coordination geometry and
acid-base Lewis capacity". N:L: Pauza, J. Pérez Cotti, L. Godar, A:M. Ferramola de
Sancovich y H.A. Sancovich. J.Inorg.Biochem. 99 No 2, 409-414, (2005).
2. "Estudios in vivo de la toxicidad del Pb2+, Cd2+ y Cu2+ y sus consecuencias en la
biosíntesis del hemo". N:L: Pauza, Y:E: Sopena de Kracoff, A:M. Ferramola de
Sancovich y H.A. Sancovich. Rev. Argent. Dermatol. 85, 154-163, (2004).
3. “Effect of in vivo administered hexachlorobenzene on epidermal growth factor receptor
levels, protein tyrosine kinase activity and phosphotyrosine content in rat liver". Andrea
S. Randi, Horacio A. Sancovich, Ana M. Ferramola de Sancovich, Andrea I. Loaiza,
Rodolfo A. Kölliker Frers, María F. Spinelli and Diana L. Kleiman de Pisarev. Biochem.
Pharmacol, 65, 1495-1506, (2003).
4. "Ontogeny of 5-aminolevulinic dehydratase and porphobilinogen deaminase activities
in the yolk sac membrane and liver of chick embryos". N:L: Pauza, Y:E: Sopena de
Kracoff, A:M. Ferramola de Sancovich and H.A. Sancovich. British Poultry Sci. 43, 196203 (2002).
5. "Ontogenia y algunas propiedades de la enzima δ-aminolevúlico dehidrasa de
embriones de pollo: modelo para el estudio de la actividad porfirinogénica de
drogas".N.L.Pauza, Y.E.Sopena de Kracoff, A.M.Ferramola de Sancovich y
H.A.Sancovich. Rev. Argent. Dermatol. 82, 76-86 (2001).
Laboratorio de Hemostasia y Trombosis (Lucía Kordich y Beatriz Sassetti)
Publicaciones en revistas internacionales
1. Influence of homocysteine on fibrin networks lysis.
Lauricella AM, Quintana IL, Sassetti B, Castañon M, Kordich L. Trabajo enviado a
Blood Coagulation & Fibrinolysis. Código de recepción: BCF- 05147. Estado actual: en
corrección según las observaciones de los referees.
2. Thrombotic events of arteriovenous fistulae in hemodialysis patients related to the
C677T thermolabile variant of methylene tetrahydrofolate reductase.
Trimarchi H, Genoud V, Schropp J, Castañon M, Freixas E, Forrester M, Pereyra H,
Kordich L.
The Journal of Vascular Access 2004; 5: 83-88
3. Associated thrombophilic defects in essential thrombocythaemia: Their relationship
with clinical manifestations
Kornbliht L, Heller P, Correa G, Castañon M, Genoud V, Vassallu P, Sarano J, Kordich
L, Molinas F
Thromb Res. 2003; 112(3):131-135.
4. Effects of homocysteine thiol group on fibrin networks: another possible mechanism of
harm.
Lauricella AM, Quintana IL, Kordich LC.
Thromb Res. 2002; 107(1-2):75-79.
5. Markers of platelet, endothelial cell and blood coagulation activation in leprosy
patients with antiphospholipid antibodies.
Martinuzzo ME, de Larranaga GF, Forastiero RR, Pelegri Y, Farina MH, Alonso BS,
Kordich LC, Carreras LO.
Clin Exp Rheumatol. 2002; 20(4):477-83.
6. Unsuspected hyperhomocysteinemia in chronically anticoagulated patients.
Murua A, Quintana I, Galarza C, Alfie J, Kordich L.
Blood Coagul Fibrinolysis. 2001; 12(1):79-80.
7. Low plasma protein Z levels in patients with antiphospholipid antibodies.
B. Steffano, R. Forastiero, M. Martinuzzo, L. Kordich.
8. Increased lipid peroxidation correlates with platelet activation but not with markers of
endotelial cell and blood coagulation activation in patients with antiphospholipid
antibodies.
Martinuzzo MM, Forastiero RR, Kordich LC, Carreras LO
Br J Haematol. 2001; 114 (4):845-51.
9. Prevalence of hyperhomocyteinemia in an elderly population.
Janson J., Murúa A., Quintana I., Galarza C., Pzygoda P., Waisman G., Cámera L.,
O’Flaherty M., Kordich L., Morales M. Cámera M.
American Journal of Hypertension 2001; 15(5): 394-397
10. Nitric oxide and its relationship with biochemical parameters in liver transplantation.
NL Zanaro, MC Romero, F Duek, O Imvertarza, J Lendoire, B Sassetti. Clinical
Chemistry and Laboratory Medicine 39:932-936, 2001.
11. Endothelial dysfunction, nitric oxide and platelet activation in Hypertensive and
diabetic type II patients. MS.Ouviña, NL Zanaro, RD La Greca, B. Sassetti.
Thrombosis Research, 102: 107-114, 2001.
12. Prevalence of three prothrombotic polymorphisms. Factor V G1691A, factor II
G20210A and methylenetetrahydrofolate reductase (MTHFR) C 677T in Argentina. On
behalf of the Grupo Cooperativo Argentino de Hemostasia y Trombosis.
Genoud V, Castanon M, Annichino-Bizzacchi J, Korin J, Kordich L.
Thromb Res. 2000; 100(3):127-31
13. Validation of an enzyme immunoassay for the determination of total homocysteine in
plasma.
Quintana I, Freeman D, Galarza C, Murua A, Spence JD, Kordich L.
14. Plasmatic homocysteine response to vitamin supplementation in elderly people.
Murua AL, Quintana I, Janson J, Batista M, Camera MI, Kordich LC.
Thromb Res. 2000; 100(6):495-500.
Publicaciones en revistas nacionales
1. Hiperhomocisteinemia. ¿Factor de riesgo trombótico?
Quintana Irene.
Acta Bioquímica Clínica Latinoamericana (ISSN: 0325-2957) 2005; Sup. Nº 1:1-76. Edición
especial de la revista con la publicación exclusiva.
2. Efecto de la concentración de citrato de sodio sobre las pruebas de hemostasia.
Duboscq C., Kordich L.C.
Acta Bioquímica Clínica Latinoamericana. 2005; Vol. 39 N°1, 87-92.
3. Comparación de parámetros de actividad antitrombótica entre dos productos de
enoxaparina.
Korin J.D., Porterie P., Kordich L.C.
Hematología. 2004; Vol. 8, 1: 9-13.
4. Endotelina-1, óxido nítrico y Factor von Willebrand en pacientes hipertensos
diabéticos tipo 2.
Ouviña SM, Palmer L, Sassetti B. Acta Bioquímica Clínica Latinoamericana, 38(4): 471476, 2004.
5. Homocisteinemia de la población de Buenos Aires: Una realidad alejada de la
idealidad.
Quintana I., Castañon M., Murúa A., Kordich L.
Hematología (ISSN 0329-0379) 2002; 6 (1): 2-7.
6. The C677T Thermolabile variant of Methilene Tetra Hydrolfolate Reductase on
Homocysteine, Folate and Vitamin B12 in a Hemodialysis Center.
Trimarchi H., Genoud V., Schiel A., Castañon M.M., Freixas E., Diaz M.L., Schropp D.,
Pereyra H., Kordich L.
Medicina (Buenos Aires) 2002; 62: 149-153.
7. El óxido nítrico y las enzimas en trasplante hepático: perfiles evolutivos.
Zanaro NL, Romero MC, Imvertarza O, Sassetti B. Acta Bioquímica Clínica
Latinoamericana, 4: 575-581, 2002.
8. El camino L-arginina-óxido nítrico y su rol en presencia de injuria de células
endoteliales vasculares.
NL Zanaro, MV Silva, SM Ouviña, AS Haedo, B Sassetti. Anales de la Fundación
Alberto J Roemmers. 14: 593-607, 2001.
9. Acción del clonixinato de lisina sobre la función plaquetaria.
EH. Kramer, B. Sassetti, A. Kaminker, AR. De Los Santos, ML. Martí, G. Di Girolamo.
Medicina 60: 301-307, 2001.
10. Hiperhomocisteinemia: Un factor de riesgo para enfermedad coronaria, cerebral
y periférica, muy común, fácilmente corregible, pero aún no reconocido. Galarza C.,
Murúa A., Janson J, Quintana I., Kordich L,Cámera M.
Revista Argentina de Medicina (ISSN 1515-3460) 2000; II-2: 83-97
Libros
1. Fundamentos para el manejo práctico en el laboratorio de hemostasia.
Editado por el Grupo Cooperativo Argentino de Hemostasia y Trombosis. 2003.
ISBN 987-21580-0-2.
Editora en jefe: Lucía C. Kordich
(Diferentes capítulos desarrollados por el Grupo de Investigación: Beatriz Sassetti, Irene
Quintana, Ana María Lauricella, M. Mercedes Castañon)
Laboratorio de Apoptosis y Cáncer (Elba Vázquez y Mónica Kotler)
Publicaciones
1. Personalized therapy: an interdisciplinary challenge. Vazquez E. Personalized
Medicine 1 (2004) 127-130. Invitada a escribir un artículo para el fascículo de
lanzamiento).
2. Immunohistochemical analysis of HO1 in preneoplastic and neoplastic lesions during
chemicl hepatocarcinogenesis. Caballero F, Meiss R, Gimenez A, Batlle A & Vazquez E
Int J Exp Pathol 85 (2004) 213-222.
3. Cell cycle arrest and modulation of HO1 expression induced by acetylsalicylic acid in
hepatocarcinogenesis. Sacca P., Caballero F., Batlle A. & Vazquez E. Int. J. Biochem.
Cell Biol. 36 (2004) 1945-1953.
4. p21 modulates threshold of apoptosis induced by DNA-damage and growth factor
withdrawal in prostate cancer cells. Martinez L., Yang J., Vazquez E., Rodriguez-Vargas
M, Olive M., Hsieh J., Logothetis C & Navone N. Carcinogenesis 23 (2002) 1289-1296.
5. 5-aminolevulinic acid cytotoxic effects on human hepatocarcinoma cell lines. De
Siervi A., Vazquez E., Rezaval C., Rossetti MV. & Batlle A. BMC Cancer 2 (2002) 6-12.
6. Interaction of cimetidine with P450 in a mouse model of hepatocarcinogenesis initiation.
Caballero F., Gerez E., Batlle A. & Vazquez E. Br. J. Cancer 86 (2002)630-635.
7. On the promoting action of tamoxifen in a model of hepatocarcinogenesis induced by pdimethyl-aminoazobenzene in CF1 mice. Caballero F., Gerez E., Oliveri L., Falcoff N.,
Batlle A. & Vazquez E. Int. J. Biochem. Cell Biol. 33 (2001) 681-690
8. Preventive aspirin treatment of streptozotocin induced diabetes: blockage of oxidative
status and revertion of heme enymes inhibition. Caballero F., Gerez E.; Batlle A. &
Vazquez E. Chemico-Biological Interactions 126 (2000) 215-225
9. A strategy for introducing undergraduate students to protein structure. Noriega G. &
Vazquez, E. Biochememistry and Molecular Biology Education 28 (2000) 200-202
1. On the promoting action of tamoxifen in the p-dimethylaminoazobenzene induced
hepatocarcinogenesis CF1 mice model and the cytoprotective role of heme oxygenase. E.
Vazquez, E. Gerez, F. Caballero, L. Oliveri, N. Falcoff, M.L. Tomaro & A. Batlle. En:
Heme Oxygenase in Biology and Medicine (Eds. N.G.Abraham, J. Alan, K. Nath)
Kluwer Academic/Plenum. (2002) pp 469-480.
Revisión de material didáctico
Multimedia in Biochemistry: BioRom 2005 (Software Review) Vazquez E. Biochem.
Molec. Biol. Educ.32 (2004) 419.
Laboratorio de Toxicología y Química Legal: Destino y efectos de contaminantes
químicos (Noemí Verrengia)
Publicaciones
1. Influence of humic acids on the toxicity of cadmium to Lumbriculus variegatus.
M.N. Piol A.G. López, L.A. Miño, M. dos Santos Afonso, N.R. Verrengia Guerrero.
Revista de la Sociedad de Toxicología Brasilera.
En etapa de revisión, por correcciones menores.
2. Influence of artificial particles on lead bioavailability and bioaccumulation by
Lumbriculus variegatus. Potential use in chemical remediation processes. L.A. Miño, S.
Folco, A.M. Pechén de D'Angelo. N.R. Verrengia Guerrero. Journal: Chemosphere.
2005, publicado en la Web desde el 16/9/2005.
3. Comparative study on two freshwater invertebrates for monitoring environmental lead
exposure. J. Aisemberg, D.E. Nahabedian, E.A. Wider, N.R. Verrengia Guerrero (2005).
Toxicology Vol. 210: 45-53.
4. Influence of particle characteristics and organic matter content on the bioavailability
and bioaccumulation of pyrene by clams. N.R.Verrengia Guerrero, M.G. Taylor, E.A.
Wider, K. Simkiss (2003). Environmental Pollution Vol. 121: 115-122.
5. Evidence of differences in the biotransformation of organic contaminants by aquatic
invertebrates. N.R.Verrengia Guerrero, M.G. Taylor, N.A. Davies, M.A.M. Lawrence,
P.A. Edwards, K. Simkiss, E.A. Wider (2002). Environmental Pollution Vol. 117: 523530
6. Modeling pentachlorophenol (PCP) bioavailability and accumulation by the freshwater
fingernail clam Sphaerium corneum using artificial particles and humic acids.
N.R.Verrengia Guerrero, M.G. Taylor, E.A. Wider, K. Simkiss (2001). Environmental
Toxicology and Chemistry Vol. 20: 2757-2763.
7. Analysis of some factors that may modify the bioavailability of cadmium and lead by
Biomphalaria glabrata. N.R.Verrengia Guerrero, D.E. Nahabedian, E.A. Wider (2000).
Environmental Toxicology and Chemistry Vol. 19: 2762-2768.
1. Biomphalaria glabrata. Utilización de sistemas mixtos para evaluación de riesgo. E.
A. Wider, N.R. Verrengia Guerrero (2000). Acta Toxicológica Argentina, Vol. 8: 27-28.
María del Carmen Vila
Publicaciones
1. C.N. Martini, S.G. Vaena de Avalos y M.C. Vila. ACTH stimulates the release of
alkaline phosphatase through Gi-mediated activation of a phospholipase C and the release
of inositolphosphoglycan. Molecular and Cellular Biochemistry (2004) 258, 191-199.
Laboratorio de Biología Tumoral (Rosa Wainstok)
Publicaciones
1. Innate NKT Lymphocytes Confer Superior AdaptiveImmunityVia Tumor Capturing
Dendritic Cells. Liu K., Idoyaga J., Charalambous A., Fujii S., Bonito A., Mordoh J.,
Wainstok R., Bai X., LiuY., Steinman R. The Journal of Experimental Medicine (2005)
Aceptado para su publicación
2. Isolation and molecular characterization of a mouse renal microvascular endothelial
cell line. Gazzaniga S., Gonzalez L., Mantovani A., Vecchi A., Wainstok R In Vitro
Cellular and Developmental Biology- Animal 40: 82-88 (2004).
3. Tissue expression of platelet endothelial cell adhesion molecule-1 and pre and
postnatal murine development. Calabrese G., Wainstok R. BIOCELL 28: 251-258
(2004)
4. Dendritic cells charged with apoptotic tumor cells induce long- lived protective CD4+
and CD8+ T cell immunity against B16 melanoma. Goldszmid R., Idoyaga J., Bravo A.I.,
Steinman R., Mordoh J., Wainstok R.
J. of Immunology 171: 5940-5947 (2003)
5. Inflammatory changes after cryosurgery- induced necrosis in human melanoma
xenografted in nude mice. Gazzaniga, S.N., Bravo, I., Goldszmid, S.R., Maschi, F.,
Martinelli, J., Mordoh, J., Wainstok, R.
Journal of Investigative Dermatology 116 (5) : 664 (2001)
1. Quimioquinas, proteinas atractivas y promiscuas que empiezan a destacarse en el
escenario de la inflamación y la inmunidad. Wainstok R.
Química Viva, año 2, Vol 2 (2003)
Grupo interdisciplinario de investigación de Fisiología del metabolismo oxidativo
(Evi Wider y Martín Ansaldo)
Publicaciones
1. Comparative study on two fresh water invertebrates for monitoring environmental lead
exposure. J. Aisemberg, D. Nahabedian, E. Wider & N. Verrengia Guerrero. Toxicology
(2005). 210(1): 45-53.
2. Chemical and biochemical changes of pumpkin (Cucumis Moschata, Duch.) tissue in
relation to osmotic stress. M F de Escalada Pla, N.M.A:Ponce, E.A.Wider, C. Stortz, A
M.Rojas & L. N.Gerchenson. Journal of the Science of Food and Agriculture. (2005)
85(11):1852-1860. ISSN 1097-0010.
3. Oxidative stress generated by diesel seawater contamination on the digestive gland of
the Antarctic limpet Nacella cocinna. M. Ansaldo, R. Najle and C.M. Luquet. Marine
Environmental Research. (2005). 59: 381-390.
4. Oxidative stress generated by diesel seawater contamination on the digestive gland of
the Antarctic limpet Nacella cocinna. M. Ansaldo, R. Najle and C.M. Luquet. Marine
Environmental Research. (2005). 59: 381-390.
5. Differential growth of the barnacle Notobalanus flosculus (Archaeobalanidae) onto
artificial and live substrates in the Beagle Channel, Argentina. Leonardo A. Venerus,
Javier A. Calcagno, Gustavo A. Lovrich and Daniel E. Nahabedian. Helgoland Marine
Research. 2005. 59:196 – 205. ISSN: 1438-387X .
6. Modeling pyrene bioavailability and accumulation by Sphaerium corneum using
artificial particles and humic acids. N.R.Verrengia Guerrero, M.G. Taylor, E.A. Wider K.
Simkiss. Environmental Pollution. (2003). 121(1): 115-122.
7. Evidence of differences in the biotransformation of organic contaminants in three
species of freshwater invertebrates. N.R. Verrengia Guerrero, M.G. Taylor, N.A. Davies,
M.A.M. Lawrence,
P.A.Edwards, K. Simkiss, E.A. Wider. Environmental Pollution
(2002).117(3): 523-530.
8. Acute and chronic effects of cadmium on blood homeostasis of an estuarine crab,
Chasmagnathus granulata, and the modifying effect of salinity”. E.M. Rodriguez, R.
Bigi, D.A. Medesani, V.S. Stella, L.S. Lopez, P.A. Rodriguez Moreno, J.M. Monserrat,
G.N. Pellerano and M. Ansaldo. Brazilian Journal of Medical and Biological Research.
(2001) 34:509-518.
9. Analysis of some factors that may modify the bioavailability od cadmium and lead by
Biomphalaria glabrata. N.R. Verrengia Guerrero, D.E. Nahabedian y E.A. Wider. Environ
Toxicol & Chem.. (2000)19:2762-2768.
10. Histopathological changes in gills of the estuarine crab Chasmagnathus granulata
(Crustacea-Decapoda) following acute exposure to ammonia”. M. de Freitas Rebelo,
E.M. Rodriguez, E.A. Santos y M. Ansaldo. Comp. Biochem. and Physiology. (2000)
C125: 157-164.
11. Bimodal breathing in the estuarine crab Chasmagnathus granulata Dana 1851.
Physiological and morphological studies. J. Halperin, M. Ansaldo, G.N. Pellerano and
C.M. Luquet. Comp. Biochem. and Physiology (2000) A126: 341-349.
12. Antioxidant levels from different Antarctic fish caught around South Georgia’s
Islands and Shag Rocks”. M. Ansaldo, P.A. Evelson, C.M. Luquet, J.M. Polo, S. Llesuy.
Polar Biology. (2000) 23, 3: 160-165.

Período 2000-2005 - Departamento de Quimica Biologica

Transcripción

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