Science and Society Department

Table of Contents
Home
CBMSO Science and Society Department
José Antonio López Guerrero
Science and
Society
Department
Next
Science and Society Department
Table of Contents
Section Contents
Home
CBMSO Science and Society Department
Research Summary
Exit
Research Summary
Staff
Publications
CBMSO 2013-2014
Within the framework of the CBMSO Scientific Culture Program, The Department of Scientific Culture of the
CBMSO (DCC-CBMSO) has collaborated in the following activities (2013-14): 1) XIII (2013) and XIV (2014)
Scientific Weeks in Madrid. In this regard, several projects were carried out in the CBMSO –some of them financially supported by FECYT (Spanish Foundation for Science and Technology)-, complementing the annual
program of guided visits of Secondary School students to our Research Centre. The CBMSO is one of the
most active Centres of the CSIC and UAM (Spanish Board of Scientific Research) in such tasks. 2) Collaboration with the Science and Society Madri+d Programme, involving the management of a scientific and cultural
Blog (awarded by the Autonomous Community of Madrid in 2012) and the providing of several information
for the scientific e-diary “Notiweb” (http://www.madrimasd.org/cienciaysociedad). 3) Developing of an Institutional Facebook and Twitter Website “Departamento de Cultura Científica. Centro de Biología Molecular”
and a weekly-updated Institutional Website about Social Communication of Science (http://web4.cbm.uam.es/
joomla-rl/index.php/es/servicios/cultura-cientifica?id=1175). 4) Weekly Mi+dTV and UNEDtv Scientific Culture
Programme “3x3 TV news” (http://www.madrimasd.org/informacionidi/madrimasd-tv/default.asp).
5) Participation in several seminars in High Schools and Secondary School Centers. 6) Participation in the
Madrid Science Fair “Alcobendas Weekend Science Fair 2014”. 7) Organization (2013-2014) and coordination of the “Biotechnology Explorer” course for secondary school teachers. 8) Finally, as a CBMSO member,
the DCC Director periodically colaborates with the magazine “El Cultural”, The Journal of Feelsynapsis and
Principia –aimed to items of scientific culture -, the Spanish National TV (TVE; La 2), the Spanish National
Radio (Radio 5 –“Entre Probetas” and “El Laboratorio de JAL”-, Radio 1 –“A Hombros de Gigantes- and Radio
Exterior –“Marca España”-) and Radio Utopía.
Further information: http://web4.cbm.uam.es/joomla-rl/index.php/es/servicios/cultura-cientifica
Moreover, the research group of NeuroVirology aims at the study of the effect of HSV-1 on neurodegeneration,
demyelinating disease and transcytosis in both immature and differentiated myelin-producing oligodendrocytic
cells. In addition to cell susceptibility the role of the major cell receptors for viral entry was assessed. In general, the results revealed that OPC (oligodendrocyte precursor cells) and HOG cells cultured under differentiation conditions became more susceptible to HSV-1. On the other hand, viral infection induced morphological
changes corresponding to differentiated cells, suggesting that HSV-1 might be inducing cell differentiation.
Colocalization of HVEM and nectin-1 with viral particles were also observed, suggesting that these two major
HSV-1 receptors are functional in HOG cells. Finally, electron microscopy assays indicated that HSV-1 may be
also entering OLs by macropinocytosis depending on their differentiation stage.
Previous
Science and Society Department
Table of Contents
Next
Section Contents
Home
CBMSO Science and Society Department
Exit
Research Summary
Staff
Figure 1. Participation in the Madrid Science Fair
“Alcobendas Weekend Science Fair 2014”
Publications
Figure 2. Infection of oligodendrocytes by HSV-1
CBMSO 2013-2014
Previous
Science and Society Department
Table of Contents
Next
Section Contents
Home
CBMSO Science and Society Department
Director:
José Antonio López Guerrero
Exit
Technical Secretariat:
Almudena Hernando Bellido
Research Summary
Staff
Publications
Scientific Staff:
Antonio Jesús Crespillo Alguacil
Collaborators:
Florencia Cavodeassi Madarro
Elena Campos Sánchez
CBMSO 2013-2014
Previous
Science and Society Department
Section Contents
Table of Contents
Home
CBMSO Science and Society Department
Publications
Bello-Morales R, Antonio Jesús Crespillo, Beatriz García, Luis Ángel Dorado, Beatriz Martín, Enrique Tabarés,
Claude Krummenacher, Fernando de Castro and López-Guerrero JA. (2014). “The effect of cellular differentiation on HSV-1 infection of oligodendrocytic cells”. PLoS One. 9:e89141.
Delgado-García M, Matesanz F, Alcina A, Fedetz M, García-Sánchez MI, Ruiz-Peña JL, Fernández O, Pinto
Medel MJ, Leyva L, Arnal C, Delgado C, López Guerrero JA, González-Pérez A, Sáez ME, Villar LM, AlvarezCermeño JC, Picón C, Arroyo R, Varadé J, Urcelay E, Izquierdo G1, Lucas M. (2014) “ A new risk variant for
multiple sclerosis at the immunoglobulin heavy chain locus associates with intrathecal IgG, IgM index and
oligoclonal bands”. Mult.Scler. Nov 12. pii: 1352458514556302.
Exit
Social communication of science:
Campos, E., López-Guerrero, J.A. (2013) “Células madre. Un futuro cada vez más cercano (II)”. Journal of
Feelsynapsis 11:86-91
López-Guerrero, J.A. (2013). “Ciencia Exprés”. Ed. Elam. ISBN: 978-84-936585-3-3.
Research Summary
Staff
Publications
Campos, E., López-Guerrero, J.A. (2013) “Células madre. Un futuro cada vez más cercano (III)”. Journal
of Feelsynapsis 12:10-17
Campos, E., López-Guerrero, J.A. (2013) “Células madre. Un futuro cada vez más cercano (III)”. Journal
of Feelsynapsis 13:11-13
López-Guerrero, J.A. (2013). “El experimento más importante se realiza sin controles”. Journal of Feelsynapsis, 13:39-48.
López Guerrero, J.A. and Bernardo Herradón (2013). “Breakthrough of the Year”. An. Quím. 109(4), 355–362.
López Guerrero, J.A. and Bernardo Herradón. (2014). “Hitos científicos de 2013”. Journal of Feelsynapsis, 14: 60-72.
López-Guerrero, J.A. (2014). “38th Annual International Herpesvirus Workshop 2014”. Virología, 17:26-27.
.....
López-Guerrero, J.A. El Cultural:
01/03/2013 “La familia SARS ataca de nuevo”
16/05/2013 “Clonación terapéutica versus clonación humana”
05/07/2013 “La genética pone al cáncer contra las cuerdas”
08/11/2013 “Virus, de patógeno a herramienta”
20/09/2013 “Sí, es una cuestión de sexo”…
28/02/2014 “De la Esclerosis Múltiple a la enfermedad de Crohn”
12/08/2014 “Los puntos calientes del Ébola”
17/05/2013 “La gripe aviar no da respiro”
27/12/2013 “Hitos del 2013”
23/05/2014 “Ébola, MERS, Dengue… Guía viva de los virus”
26/12/2014 “ Hitos del 2014”
CBMSO 2013-2014
11/01/2013 “Nuevos virus, viejas infecciones”