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Program Multidisciplinary workshop on the analysis of medical, physiological and biological data Auditorium of the Complex Science Centre (C3) in the Cultural Zone of the National Autonomous University of Mexico (UNAM), 23-25 November 206 Wednesday, November 23rd: Data-mining techniques Thursday, November 24th: Times-series analysis Friday, November 25th: Quantitative image analysis Scientific committee • Ana Leonor Rivera (ICN-UNAM, C3-UNAM) • Karla Paola García Pelagio (FCiencias-UNAM, Red de Física Médica) • Ruben Fossion (ICN-UNAM, C3-UNAM, Red de Física Médica) • María Ester Brandan (IF-UNAM, Red de Física Médica) página 1 Wednesday, 23/11: Data-mining techniques 09:00-09:30 Registration & inauguration TOPIC 1: MULTIFACTORIAL VS. UNIFACTORIAL STUDIES 09:30-10:15 Overview talk Christopher Stephens (ICN-UNAM, C3-UNAM) The challenges of modelling human health 10:15-11:00 10:15-10:30 Topical contributions A Natalia Mantilla Beniers (FCiencias-UNAM, C3-UNAM) Reporta: una base de datos epidemiológicos generada por participación ciudadana Jonathan Easton (C3-UNAM) Data mining techniques applied to Obesity: Eating patterns and attitude to Obesity Flores, Hugo (C3-UNAM) Prediction of the prevalence of diabetes mellitus type 2 from risk factors in the PREVENIMSS questionaires 10:30-10:45 10:45-11:00 11:00-11:30 Coffee 11:30-12:30 11:30-11:45 Topical contributions B Daniel Diaz,Daniel (C3-UNAM) Burden of intestinal infectious disease due to protozoa and bacteria in Mexico Juan C. Toledo-Roy (C3-UNAM) Improved diagnostic of intensive care patients using computational classifiers Lorena Parra (INGER) Estudio de pruebas de desempeño físico mediante el análisis de redes neuronales Dolores Mino-Leon (INGER) Patrones de multimorbilidad en adultos mayores 11:45-12:00 12:00-12:15 12:15-12:30 12:30-14:00 Discussion panel: Multifactorial vs. unifactorial studies Moderator:Natalia Mantilla Beniers (FCiencias-UNAM, C3-UNAM) Panelists: Luis Miguel Gutiérrez Robledo (INGER), Jean Francois Dartigues (Université de Bordeaux), Christopher Stephens (ICNUNAM, C3-UNAM) página 2 14:00-15:00 Lunch TOPIC 2: MODELING VS. DATA MINING: APPLICATIONS TO CANCER 15:00-15:45 Overview talk Héctor Morales Barcenas (UAM Iztapalapa) Inverse problems and mathematical modeling guided by data 15:45-16-15 Coffee 16:15-17:00 16:15-16:30 Topical Contributions C Evangelina Figueroa Medina (INCMNSZ) Clinical outcomes and beam quality correlations on skin cancer radiotherapy management in Mexico Diddier Prada (INCAN) Biomarcadores en Cáncer de Mama de Mujeres Mexicanas Jennifer Enciso (IMSS) Development of a multi-modular boolean network for the study of acute lymphoblastic leukemia 16:30-16:45 16:45-17:00 17:00-18:00 Discussion panel: modeling vs. data-mining Moderator: TBA Panelists: TBA página 3 Thursday, 24/11: Time-series analysis 09:00-09:30 Registration TOPIC 3: CROSS-CORRELATION ANALYSIS OF SIMULTANEEOUS TIME SERIES 09:30-10:15 Overview talk Maia Angelova (Northumbria University at Newcastle, UK) The effect of synchronization between heart rate and respiration on the performance of physical or cognitive tasks 10:15-11:00 10:15-10:30 Topical contributions A Claudia Lerma (INCIC) Cross recurrence plot analysis between heart rate and systolic blood pressure variability Norma Paola Martínez García (INCMNSZ) Systolic blood pressure and inter beat interval identification and baroreflex sensitivity estimation in patients with chronic renal failure Daniela Margarito Segundo (FCiencias-UNAM) Development of a wearable to measure correlation between oximetry and patient activity 10:30-10:45 10:45-11:00 11:00-11:30 Coffee 11:30-12:15 Overview talk Bruno Estañol (INCMNSZ) Venous and arterial blood flow 12:15-14:00 Discussion panel: Cross-correlation analysis vs. analysis of individual time series Moderator: TBA Panelists: TBA 14:00-15:00 Lunch página 4 TOPIC 4: PHYS(IOL)ICAL MEANING OF TIME-SERIES STATISTICS 15:00-15:45 Overview talk Aneta Stefanovska (Lancaster University, UK) Complex nonlinear dynamical systems and how to analyse their time series 15:45-16:30 15:45-16:00 Topical contributions B Leonardo I Zapata-Fonseca (PECEM-UNAM, Max Planck, Germany) Time-series analysis for studying social cognition Ana Leonor Rivera (ICN-UNAM, C3-UNAM) Looking for biomarkers in physiological time series Karla Paola García Pelagio (FCiencias-UNAM) Actigraphy and temperature circadian rhythms in an obese population 16:00-16:15 16:15-16:30 16:30-17:00 Coffee 17:00-18:00 17:00-17:15 Topical Contributions C Dobromir Dotov (INB-UNAM) Quantifying rigid patterns of coordination across different motor skills in Parkinson's disease Lesli Alvarez Millán (C3-UNAM) Dynamics of physiological variables during 150m walking in frail and non-frail elderly adults Octavio B. Lecona (UACM, C3-UNAM) Homeostasis from a time-series perspective: Application to Daisy World Ruben Fossion (ICN-UNAM, C3-UNAM) Homeostasis from a time-series perspective: Application to heart rate and blood pressure in type-2 diabetes mellitus 17:15-17:30 17:30-17:45 17:45-18:00 18:00-19:00 Discussion panel: Phys(iol)ical interpretation of time-series statistics Moderator: TBA Panelists: TBA página 5 Friday, 25/11: Quantitative image analysis 09:00-09:30 Registration TOPIC 5: NOVEL TECHNIQUES LOOKING FOR NEW APPLICATIONS 09:30-10:15 Overview talk Stephanie Harmon (University of Wisconsin, USA) Techniques, applications, and challenges in quantitative image analysis 10:15-11:00 10:15-10:30 Invited Short Contributions Jorge Alberto Marquez Flores (CCADET-UNAM) Textural Analysis in Medical Images Alfonso Gastélum (HGM & CCADET-UNAM) Textural based Labeling Models and Form Studies M. Elena Martínez Pérez (IIMAS-UNAM) Geometrical and Morphological Analysis of Vascular Branches from Fundus Retinal Images 10:30-10:45 10:45-11:00 11:00-11:30 Discussion panel: Novel techniques for image analysis Moderator: TBA Panelists: TBA 11:30-12:00 Coffee TOPIC 6: REAL-LIFE PROBLEMS LOOKING FOR SOLUTIONS 12:00-14:30 12:00-12:15 12:15-12:30 12:30-12:45 12:45-13:00 Topical contributions A J. J. Galvez-Gamboa (CIDETEC-IPN) Mitotic Cells Recognition of Breast Cancer in Histopathology Images Using Deep Learning Techniques Lizbeth de la Cruz (FMedicina-UNAM) Fluorescence image analysis of calcium channel regulation by PIP2 in pancreatic β-cells Carlos Alberto Reynoso (INNN) Quantification and image quality of SPECT images Sarahí Rosas González (INNN) Experimental evaluation of the dynamic PET image accuracy página 6 13:00-13:15 13:15-13:30 13:30-13:45 13:45-14:00 14:00-14:15 14:15-14:30 Liz Ayala Domínguez (IF-UNAM) Quantitative evaluation of vascular features of tumors with contrastenhanced X-ray imaging Francisco Berumen (INCAN) A pixel-based classification of enhancement kinetic curves in breast magnetic resonance María Julieta Mateos (PCF-UNAM) Análisis de textura en imágenes de mamografía digital con medio de contraste Eurídice Rioja Guerrero (INCMNSZ) Correlation of the internal dosimetry with quantitative analysis of the I131 uptake images, age and thyroid profile tests for thyroid cancer patients Sirio Bolaños Puchet (UAM Iztapalapa) Estimation of the internal absorbed dose distribution in a solid tumor from quantified preclinical SPECT/CT Arturo Avendaño (Fciencias-UNAM) PET imaging of presynaptic and postsynaptic function to evaluate Parkinson’s disease 14:30-15:00 Discussion panel: Real-life problems looking for solutions Moderator: TBA Panelists: TBA 15:00-16:00 Lunch + book presentation “El fotón de Asclepio: El ojo y el arma de la medicina moderna”, finalist of the Ruy Pérez Tamayo Award to the best science-for-general-public book 2015, by author Juan Pablo Cruz Bastida. 16:00-17:00 María-Ester Brandan, Coordinator of the Mexican Network on Medical Physics, Report of the 2016 activities by the Mexican Network on Medical Physics, and proposed activities for 2017. 17:00 Closure página 7