Summary Slide - Professional Heart Daily

Summary Slide - Professional Heart Daily

Low-Dose Aspirin for Primary Prevention of Cardiovascular Events in Elderly
Patients With Multiple Atherosclerotic Risk Factors: A Randomized Controlled
Trial
Purpose: To evaluate the outcome of using low dose aspirin for primary prevention in a
population of elderly Japanese patents.
Trial Design: Multicenter, randomized, blinded trial. 14,464 high-risk patients (HTN, DM, and/or
elevated lipids). Median F/U = 5 years years. Randomized 1:1 to enteric coated aspirin 100
mg/day or no aspirin along with their regular medications. Mean age = 70.6 years.
Primary Endpoint: cardiovascular death MI, stroke; non-fatal stroke or MI.
Trial Results
P value
Low-dose aspirin
2.96%
No aspirin
2.77%
0.544
Conclusions: Low-dose aspirin in this elderly population did not reduce atherosclerotic
cardiovascular events.
Presented by: Yasuo Ikeda, AHA Scientific Sessions 2014, Chicago, IL
© 2014, American Heart Association. All rights reserved